{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T01:01:43Z","timestamp":1791594103071,"version":"4.3.4"},"reference-count":32,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2023,7,25]],"date-time":"2023-07-25T00:00:00Z","timestamp":1690243200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005036","name":"Universitetet i Bergen","doi-asserted-by":"publisher","award":["2019\/26961\u2010ELRI"],"award-info":[{"award-number":["2019\/26961\u2010ELRI"]}],"id":[{"id":"10.13039\/501100005036","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Most studies on factors affecting the risk of preeclampsia have not separated preterm from term preeclampsia, and we still know little about whether the predisposing conditions have a differentiated effect on the risk of preterm and term preeclampsia. Our aim was to assess whether diabetes type 1 and 2, chronic kidney disease, asthma, epilepsy, rheumatoid arthritis and chronic hypertension were differentially associated with preterm and term preeclampsia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and methods<\/jats:title><jats:p>This is a nationwide, population\u2010based cohort study containing all births registered in the Medical Birth Registry of Norway from 1999 to 2016. Multinomial logistic regression analysis was used to estimate relative risk ratios (RRRs) with 95% confidence intervals (95% CIs), adjusting for maternal age, parity, multiple gestation and all other studied maternal risk factors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We registered 1\u2009044\u2009860 deliveries, of which 9533 (0.9%) women had preterm preeclampsia (&lt;37\u2009weeks) and 26\u2009504 (2.5%) women had term preeclampsia (&gt;37\u2009weeks). Most of the assessed maternal risk factors were associated with increased risk for both preterm and term preeclampsia, with adjusted RRRs ranging from 1.2 to 10.5 (preterm vs no preeclampsia) and 0.9\u20135.7 (term vs no preeclampsia). Diabetes type 1 and 2 (RRR preterm vs term preeclampsia 2.89, 95% CI 2.46\u20133.39 and RRR 1.68, 95% CI 1.25\u20132.25, respectively), chronic kidney disease (RRR 1.55, 95% CI 1.11\u20132.17) and chronic hypertension (RRR 1.85, 95% CI 1.63\u20132.10) were more strongly associated with preterm than term preeclampsia in adjusted analyses. For asthma, epilepsy and rheumatoid arthritis, RRRs were closer to one and not significant when comparing risk of preterm and term preeclampsia. Main results were similar when using a diagnosis at &lt;34\u2009weeks to define preterm preeclampsia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Diabetes type 1 and 2, chronic kidney disease and chronic hypertension were more strongly associated with preterm than term preeclampsia.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aogs.14642","type":"journal-article","created":{"date-parts":[[2023,7,26]],"date-time":"2023-07-26T05:01:58Z","timestamp":1690347718000},"page":"1549-1557","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Pregestational maternal risk factors for preterm and term preeclampsia: A population\u2010based cohort study"],"prefix":"10.1111","volume":"102","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8927-2253","authenticated-orcid":false,"given":"Anne Kvie","family":"Sande","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Stavanger University Hospital  Stavanger Norway"},{"name":"Department of Clinical Science University of Bergen  Bergen Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ingvild","family":"Dalen","sequence":"additional","affiliation":[{"name":"Department of Research, Section of Biostatistics Stavanger University Hospital  Stavanger Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erik Andreas","family":"Torkildsen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Stavanger University Hospital  Stavanger Norway"},{"name":"Department of Clinical Science University of Bergen  Bergen Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ragnar Kvie","family":"Sande","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Stavanger University Hospital  Stavanger Norway"},{"name":"Department of Clinical Science University of Bergen  Bergen Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nils\u2010Halvdan","family":"Morken","sequence":"additional","affiliation":[{"name":"Department of Clinical Science University of Bergen  Bergen Norway"},{"name":"Department of Obstetrics and Gynecology Haukeland University Hospital  Bergen Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,7,25]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2214-109X(14)70227-X"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(96)70056-X"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/297397"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1980.tb04419.x"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006250-200303000-00026"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1704559"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jri.2018.04.004"},{"issue":"544","key":"e_1_2_12_9_1","first-page":"e1","article-title":"Incidence of preeclampsia: risk factors and outcomes associated with early\u2010 versus late\u2010onset disease","volume":"209","author":"Lisonkova S","year":"2013","journal-title":"Am J Obstet Gynecol"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.3390\/reprodmed2030014"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22062965"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.39406.652986.BE"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2017.08.029"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/GCO.0b013e32834feb6a"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2008.105262"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199809033391004"},{"key":"e_1_2_12_17_1","first-page":"201","article-title":"Reactions of the immune system in epilepsy","volume":"5","author":"Cojocaru IM","year":"2010","journal-title":"Maedica (Bucur)"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201604-0806OC"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2431-14-101"},{"key":"e_1_2_12_20_1","unstructured":"(NICE) NIoHaCE.Hypertension in pregnancy: diagnosis and management (ng133). 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