{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T23:57:40Z","timestamp":1789343860704,"version":"build-2803163510"},"reference-count":29,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2023,9,11]],"date-time":"2023-09-11T00:00:00Z","timestamp":1694390400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>There is an ongoing debate on surgical techniques for colorectal deep endometriosis (DE) and their effects on gastrointestinal (GI) function. The aim of this study was to prospectively investigate the differences in pre\u2010 and postsurgical GI function, health profiles and pain symptoms in women undergoing colorectal surgery for symptomatic DE either with a modified segmental resection technique, so\u2010called nerve\u2010vessel sparing segmental resection (NVSSR), or full thickness discoid resection (FTDR). Complication rates and fertility outcomes were also evaluated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and methods<\/jats:title>\n                    <jats:p>A total of 162 consecutive patients, 125 (77.2%) of whom underwent NVSSR and 37 (22.8%) FTDR, were evaluated regarding complication rates. Furthermore a lower anterior resection syndrome (LARS) scores, gastrointestinal function\u2010related quality of life index\u00a0(GIQLI), pain symptoms, endometriosis health profile (EHP\u201030) parameters were analyzed pre\u2010 and post\u2010surgery in a final cohort of 121 patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      There was no difference between postsurgical prevalence of LARS in either surgery group (14\/98, 14.1% NVSSR; 2\/23, 8.6% FTDR), with significantly decreased LARS scores and increased GIQLI values before vs after surgery in both groups (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001). The overall grade III complication rate was 7\/162 (4.3%) with no significant differences between NVSSR and FTDR groups. Overall, EHP\u201030 and pain scores significantly decreased after a median follow\u2010up of 41 (\u00b1\u200917.6) months (EHP\u201030 51.1, SD 21.5 vs 12.7, SD 19.3,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001; dysmenorrhea, dyspareunia, dyschezia all\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001 both cohorts, respectively). The overall life birth rate and postsurgical pregnancy in infertile patients undergoing NVSSR and FTDR was respectively 58.1% in 25\/43 patients; 55.6% in 5\/9 patients; 56.0% in 14\/25 patients and 100% in 5\/5 patients.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>NVSSR and FTDR for symptomatic colorectal DE confer a significant amelioration of GI function reflected by decreased LARS symptoms and increased GIQLI scores with no differences in postsurgical function in between the two techniques. Both techniques confer similar complication rates and effects on pain reduction and health profiles.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/aogs.14676","type":"journal-article","created":{"date-parts":[[2023,9,11]],"date-time":"2023-09-11T07:55:56Z","timestamp":1694418956000},"page":"1347-1358","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Pain, gastrointestinal function and fertility outcomes of modified nerve\u2010vessel sparing segmental and full thickness discoid resection for deep colorectal endometriosis \u2013 A prospective cohort study"],"prefix":"10.1111","volume":"102","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9424-2208","authenticated-orcid":false,"given":"Gernot","family":"Hudelist","sequence":"first","affiliation":[{"name":"Department of Gynecology, Center for Endometriosis Hospital St. John of God  Vienna Austria"},{"name":"Rudolfinerhaus Private Clinic and Campus  Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daria","family":"Pashkunova","sequence":"additional","affiliation":[{"name":"Department of Gynecology, Center for Endometriosis Hospital St. John of God  Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9570-1165","authenticated-orcid":false,"given":"Ezgi","family":"Darici","sequence":"additional","affiliation":[{"name":"Brussels IVF, Centre for Reproductive Medicine Universitair Ziekenhuis Brussel Vrije Universiteit Brussel  Brussels Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Rath","sequence":"additional","affiliation":[{"name":"Rudolfinerhaus Private Clinic and Campus  Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-7092-9719","authenticated-orcid":false,"given":"Johanna","family":"Mitrowitz","sequence":"additional","affiliation":[{"name":"Department of Gynecology, Center for Endometriosis Hospital St. John of God  Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernhard","family":"Dauser","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Center for Endometriosis Hospital St. John of God  Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Birgit","family":"Senft","sequence":"additional","affiliation":[{"name":"Statistix Statistical Calculations Company  Klagenfurt Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9416-2438","authenticated-orcid":false,"given":"Attila","family":"Bokor","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Center for Endometriosis Semmelweis University Budapest  Budapest Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,9,11]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.26175"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00508-022-02088-x"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rbmo.2019.06.006"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/aogs.13619"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2016.06.055"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/dex336"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/aogs.13436"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/aogs.14411"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2017.09.006"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmv003"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10215183"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2022.10.009"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2020.08.015"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/aogs.14046"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/aogs.14379"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.15955"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/dew293"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/aogs.14099"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(01)01433-8"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0036-1584500"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-006-0053-5"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e3181b13ca2"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.14806"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00423-022-02705-3"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.13975"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/des322"},{"key":"e_1_2_12_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2013.04.015"},{"key":"e_1_2_12_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2013.01.131"},{"key":"e_1_2_12_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2022.09.551"}],"container-title":["Acta 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