{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T02:15:09Z","timestamp":1784859309980,"version":"3.55.0"},"reference-count":46,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,11,5]],"date-time":"2023-11-05T00:00:00Z","timestamp":1699142400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>This study aimed to investigate the impact of maternal SARS\u2010CoV\u20102 infection at the time of admission for delivery on labor process and outcomes of vaginal birth.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and methods<\/jats:title><jats:p>A cohort study was carried out at the Obstetrics Department of Anhui Provincial Hospital, China, where universal reverse transcriptase polymerase chain reaction (RT\u2010PCR) testing for SARS\u2010CoV\u20102 infection was introduced for all women admitted for labor and delivery from December 1\u201331, 2022. Women were divided into positive and negative groups based on the test result. All women having a singleton vaginal birth were included in final analysis. The effect of SARS\u2010CoV\u20102 positivity on labor process and outcomes of vaginal birth was estimated by regression analyses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among a total of 360 women included, 87 had a positive SARS\u2010CoV\u20102 test and 273 a negative test. Women in the positive group had an increased likelihood of having longer labor (median 9.3 vs 8.3\u2009hours; sB [log\u2010transformed] 0.19; 95% confidence interval [CI] 0.09\u20130.28), episiotomy (39.1% vs 23.8%; adjusted odds ratio [aOR] 2.31; 95% CI 1.27\u20134.21), grade III meconium\u2010stained amniotic fluid (19.5% vs 7.0%; aOR 2.52; 95% CI 1.15\u20135.54) and postpartum hospital stay exceeding 37\u2009hours (58.6% vs 46.5%; aOR 1.71; 95% CI 1.00\u20132.91). They had reduced rates exclusive breastfeeding (26.7% vs 39%; aOR 0.21; 95% CI 0.09\u20130.46) as well as mixed feeding (46.5% vs 52.2%; aOR 0.28; 95% CI 0.13\u20130.60) at 1\u2009week postpartum. No significant differences were observed in other aspects of labor process and birth outcomes, including the uptake of labor analgesia, postpartum hemorrhage (&gt;500\u2009mL) or neonatal outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>A positive maternal SARS\u2010CoV\u20102 test in labor among women having vaginal birth was associated with a slightly longer duration of labor, increased likelihood of episiotomy, increased incidence of grade III meconium\u2010stained amniotic fluid, a longer postpartum hospital stay and a lower rate of breastfeeding 1\u2009week postpartum. However, it did not have an adverse impact on other birth outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aogs.14704","type":"journal-article","created":{"date-parts":[[2023,11,6]],"date-time":"2023-11-06T05:13:27Z","timestamp":1699247607000},"page":"103-110","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Association of maternal SARS\u2010CoV\u20102 infection at the time of admission for delivery with labor process and outcomes of vaginal birth: A cohort study"],"prefix":"10.1111","volume":"103","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9419-8254","authenticated-orcid":false,"given":"An","family":"Chen","sequence":"first","affiliation":[{"name":"School of Public Health Zhejiang Chinese Medical University  Hangzhou China"},{"name":"Department of Public Health, Faculty of Medicine University of Helsinki  Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1997-3107","authenticated-orcid":false,"given":"Ganesh","family":"Acharya","sequence":"additional","affiliation":[{"name":"Division of Obstetrics &amp; Gynecology, Department of Clinical Science, Intervention and Technology (CLINTEC) Karolinska Institutet  Stockholm Sweden"},{"name":"Department of Clinical Medicine UiT The Arctic University of Troms\u00f8  Troms\u00f8 Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology The First Affiliated Hospital of University of Science and Technology of China (USTC)  Hefei China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Gao","sequence":"additional","affiliation":[{"name":"Medical Teaching and Research Section Anhui Open University  Hefei China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guizhi","family":"Cheng","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology The First Affiliated Hospital of University of Science and Technology of China (USTC)  Hefei China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lai","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology The First Affiliated Hospital of University of Science and Technology of China (USTC)  Hefei China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2907-6888","authenticated-orcid":false,"given":"Qianqian","family":"Ni","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology The First Affiliated Hospital of University of Science and Technology of China (USTC)  Hefei China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,11,5]]},"reference":[{"key":"e_1_2_13_2_1","unstructured":"WHO coronavirus (COVID\u201019) dashboard with vaccination data. 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