{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,7]],"date-time":"2025-04-07T04:01:56Z","timestamp":1743998516541,"version":"3.40.3"},"reference-count":19,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2024,6,14]],"date-time":"2024-06-14T00:00:00Z","timestamp":1718323200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>The objective of the study was to provide a comprehensive description of perioperative morbidity associated with robot\u2010assisted surgery (RAS) in a gynecological oncology setting in order to improve the preoperative counseling of women and support shared decision\u2010making.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and Methods<\/jats:title><jats:p>All women scheduled for intended RAS between January 2015 and December 2022 were prospectively included in an electronic morbidity database for the analyses of perioperative complications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In total, 2225 women were included. Sixty\u2010four patients (2.9%) experienced an intraoperative complication. Intraoperative complications were associated with a higher rate of conversion to laparotomy (15.6% vs. 1.8%, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), a higher rate of major postoperative morbidity (9.3% vs. 2.4%, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), and a higher rate of reoperation (9.3% vs. 1.7%, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), compared to cases without intraoperative complications. Thirty\u2010day postoperative morbidity was evaluated according to the Memorial Sloan\u2010Kettering Cancer Center Surgical Secondary Events Grading System. Grade 3\u20135 events were considered major. A total of 57 patients (2.6%) experienced a major event after surgery, postoperative rupture of the vaginal vault being the most common complication requiring surgical intervention. Conversion to laparotomy occurred in 49 cases (2.2%) and was associated with higher intraoperative blood loss (300\u2009mL vs. 25\u2009mL, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), a higher rate of postoperative major events (20.4% vs. 2.2%, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), and a higher rate of reoperation (11.8% vs. 1.6%, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our study demonstrates low rates of major perioperative morbidity and conversion to laparotomy after RAS performed by trained high\u2010volume surgeons in a gynecological oncology setting.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aogs.14852","type":"journal-article","created":{"date-parts":[[2024,6,14]],"date-time":"2024-06-14T12:35:16Z","timestamp":1718368516000},"page":"1672-1679","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Morbidity following robot\u2010assisted surgery in a gynecological oncology setting: A cohort study"],"prefix":"10.1111","volume":"103","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4145-9120","authenticated-orcid":false,"given":"Algirdas","family":"Markauskas","sequence":"first","affiliation":[{"name":"Department of Gynecology and Obstetrics Odense University Hospital  Odense Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan","family":"Blaak\u00e6r","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics Odense University Hospital  Odense Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koen Josef","family":"Traen","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics Odense University Hospital  Odense Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1946-4561","authenticated-orcid":false,"given":"Gudrun Astrid","family":"Neumann","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics Odense University Hospital  Odense Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wu","family":"Chunsen","sequence":"additional","affiliation":[{"name":"Research Unit, Department of Clinical Research in Gynecology and Obstetrics University of Southern Denmark  Odense Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lone Kjeld","family":"Petersen","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics Odense University Hospital  Odense Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,6,14]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2020.05.010"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e3182737538"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/jhq.12036"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-014-4141-4"},{"key":"e_1_2_11_6_1","unstructured":"The Danish Society for Thrombosis and Hemostasis.Guideline 2020. Accessed August 7 2023.https:\/\/dsth.dk\/pdf\/CAT_2020.pdf"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2016.06.005"},{"issue":"551","key":"e_1_2_11_8_1","first-page":"e1","article-title":"Surgical outcomes in gynecologic oncology in the era of robotics: analysis of first 1000 cases","volume":"204","author":"Paley PJ","year":"2011","journal-title":"Am J Obstet Gynecol"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e3181af36e3"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2016.11.018"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2010.08.035"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2019.09.036"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/IGC.0b013e318275c266"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.1412S3"},{"key":"e_1_2_11_15_1","first-page":"1181","article-title":"Cancer\u2010associated venous thromboembolic disease, version 2.2021, NCCN clinical practice guidelines in oncology","volume":"19","author":"Streiff MB","year":"2021","journal-title":"J Natl Compr Cancer Netw"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.19.01461"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2014.109843"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000000340"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2014.05.012"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/IGC.0000000000001084"}],"container-title":["Acta Obstetricia et Gynecologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aogs.14852","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,6]],"date-time":"2025-04-06T10:46:46Z","timestamp":1743936406000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/aogs.14852"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,14]]},"references-count":19,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2024,8]]}},"alternative-id":["10.1111\/aogs.14852"],"URL":"https:\/\/doi.org\/10.1111\/aogs.14852","archive":["Portico"],"relation":{},"ISSN":["0001-6349","1600-0412"],"issn-type":[{"type":"print","value":"0001-6349"},{"type":"electronic","value":"1600-0412"}],"subject":[],"published":{"date-parts":[[2024,6,14]]},"assertion":[{"value":"2023-08-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-04-10","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-06-14","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}