{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T10:47:50Z","timestamp":1779187670122,"version":"3.51.4"},"reference-count":24,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2024,8,4]],"date-time":"2024-08-04T00:00:00Z","timestamp":1722729600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Cesarean section at full dilatation has been associated with an increased risk of subsequent preterm birth. We hypothesized that there may be an increased risk of miscarriage in pregnancies that follow cesarean section at full dilatation. This study aimed to determine if a first\u2010term (\u226537\u2009weeks) cesarean section at full dilatation is associated with an increased risk of miscarriage in the next pregnancy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and Methods<\/jats:title><jats:p>A historical cohort study was conducted using routinely collected hospital data within the Aberdeen Maternity and Neonatal Databank (AMND). The population included were women who had a first\u2010term birth and who had a second birth recorded within the AMND. Logistic and multinomial regression was used to determine any association with miscarriage at any gestation and for early (&lt;13\u2009weeks gestation) and late (13\u201323\u2009+\u20096\u2009weeks gestation) miscarriage, with cesarean section at full dilatation defined as the exposure. Miscarriage in the second pregnancy (spontaneous loss of intrauterine pregnancy prior to 24\u2009weeks gestation) was the primary outcome.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In total, 33\u2009452 women were included. Women who had a first cesarean section at full dilatation were no more likely to have a miscarriage at any gestation than women with all other modes of first birth (including all vaginal births, planned CS, and the first stage of labor (&lt;10\u2009cm dilated CS)) [adjusted OR 0.84 (0.66\u20131.08); <jats:italic>p<\/jats:italic>\u2009=\u20090.18]. There was no association with early or late miscarriage after a CSfd, though the sample size for late miscarriage was small.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This is the first observational study to investigate the risk of miscarriage following first\u2010term CSfd. We found no association between miscarriage at any gestation following a first\u2010term CSfd compared to all other modes of first birth.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aogs.14936","type":"journal-article","created":{"date-parts":[[2024,8,5]],"date-time":"2024-08-05T06:34:20Z","timestamp":1722839660000},"page":"2092-2100","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Cesarean section at full dilatation in the first birth is not associated with an increased risk of subsequent miscarriage: A historical cohort study"],"prefix":"10.1111","volume":"103","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5320-9540","authenticated-orcid":false,"given":"Andrea","family":"Woolner","sequence":"first","affiliation":[{"name":"Aberdeen Center for Women's Health Research (ACWHR), Institute Applied Health Sciences, School of Medicine, Medical Sciences and Nutrition University of Aberdeen  Aberdeen UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edwin Amalraj","family":"Raja","sequence":"additional","affiliation":[{"name":"Medical statistics, Institute Applied Health Sciences, School of Medicine, Medical Sciences and Nutrition University of Aberdeen  Aberdeen UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6841-8601","authenticated-orcid":false,"given":"Mairead","family":"Black","sequence":"additional","affiliation":[{"name":"Aberdeen Center for Women's Health Research (ACWHR), Institute Applied Health Sciences, School of Medicine, Medical Sciences and Nutrition University of Aberdeen  Aberdeen UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,8,4]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2023.08.013"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijgo.14186"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.16566"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajo.12713"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2017.03.006"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2017.04.019"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2023.08.033"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/OGX.0b013e3182022069"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1080\/14767058.2019.1657086"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2009.04.007"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.20276"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2022.06.031"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2022.02.016"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rbmo.2021.04.007"},{"key":"e_1_2_13_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2006.06.069"},{"key":"e_1_2_13_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/aogs.13160"},{"key":"e_1_2_13_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajogmf.2023.101144"},{"key":"e_1_2_13_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyv356"},{"key":"e_1_2_13_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2005.00651.x"},{"key":"e_1_2_13_21_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0054588"},{"key":"e_1_2_13_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1989.tb03227.x"},{"key":"e_1_2_13_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2018.08.031"},{"key":"e_1_2_13_24_1","first-page":"287","article-title":"The association between prior cesarean delivery and subsequent in\u00a0vitro fertilization outcomes in women undergoing autologous, frozen\u2010thawed single euploid embryo transfer","volume":"225","author":"Friedenthal J","year":"2021","journal-title":"Obstet Gynecol"},{"key":"e_1_2_13_25_1","unstructured":"Method (multiple imputation).IBM. 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