{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T22:32:28Z","timestamp":1784586748702,"version":"3.55.0"},"reference-count":36,"publisher":"Wiley","issue":"S1","license":[{"start":{"date-parts":[[2024,10,2]],"date-time":"2024-10-02T00:00:00Z","timestamp":1727827200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>The European Working Group for Abnormally Invasive Placenta proposed a checklist of ultrasound features for the antenatal detection of placenta accreta spectrum (PAS). This study aims to assess the performance of the checklist in identifying histopathologically confirmed PAS cases in a cohort with a high pre\u2010test probability of PAS, and identify if particular features are associated with PAS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and Methods<\/jats:title><jats:p>This is a prospective multi\u2010site cohort study conducted between 2018 and 2023. Consecutive patients who underwent ultrasound assessment for suspicion of PAS were included, and the sonographic checklist was completed at the time of ultrasound. Cases were defined as PAS where they had intraoperative findings as described by the International Federation of Gynecology and Obstetrics (FIGO) grading, and histopathological findings for hysterectomy and myometrial resection cases. All non\u2010PAS cases in this study had placenta previa and at least one prior cesarean delivery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Seventy\u2010eight participants met inclusion criteria, of whom 63 (80.7%) were diagnosed with PAS. Cesarean hysterectomy was performed in 49 cases (62.8%). Overall, third\u2010trimester ultrasound performed at a median gestational age of 32\u2009weeks (IQR 30\u201334\u2009weeks) had a sensitivity of 0.84 (95% CI 0.73 to 0.92) and specificity of 0.73 (95% CI 0.45 to 0.92) for detecting PAS, with a positive and negative likelihood ratio of 3.15 (95% CI 1.35 to 7.35) and 0.22 (95% CI 0.11 to 0.41), respectively. Features most associated with PAS were abnormal placental lacunae (Odds Ratio [OR] 5.40 [95% CI 1.61 to 18.03] and myometrial thinning OR 6.87 [95% CI 1.93 to 24.4]). While many of the ultrasound features seen in PAS were also present in cases of placenta previa with prior Cesarean section, the median (IQR) number of features present in PAS cases was significantly higher than in the non\u2010PAS placenta previa group (six features [3\u20138] vs. two features [0\u20133] <jats:italic>p<\/jats:italic>\u2009=\u20090.001). No case of non\u2010PAS placenta previa had more than five features present.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The use of a standardized sonographic checklist had a high sensitivity and good specificity for the detection of PAS in this prospective cohort of well\u2010classified PAS cases.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aogs.14943","type":"journal-article","created":{"date-parts":[[2024,10,2]],"date-time":"2024-10-02T10:42:50Z","timestamp":1727865770000},"page":"56-65","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Prenatal detection of placenta accreta spectrum using a sonographic checklist"],"prefix":"10.1111","volume":"104","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6470-9364","authenticated-orcid":false,"given":"Helena C.","family":"Bartels","sequence":"first","affiliation":[{"name":"Department of Fetal Medicine National Maternity Hospital  Dublin 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College Dublin, National Maternity Hospital  Dublin Ireland"},{"name":"UCD Perinatal Research Centre University College Dublin, National Maternity Hospital  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clare","family":"C'Connor","sequence":"additional","affiliation":[{"name":"Department of Fetal Medicine National Maternity Hospital  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire","family":"Thompson","sequence":"additional","affiliation":[{"name":"University College Dublin Gynaecological Oncology Group (UCD\u2010GOG) Mater Misericordiae University Hospital and St. Vincent's University Hospital  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Donnelly","sequence":"additional","affiliation":[{"name":"Rotunda Hospital  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donal 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