{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,2]],"date-time":"2025-12-02T03:36:33Z","timestamp":1764646593006,"version":"build-2065373602"},"reference-count":67,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2025,8,14]],"date-time":"2025-08-14T00:00:00Z","timestamp":1755129600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100010805","name":"Forskningsr\u00e5det i Syd\u00f6stra Sverige","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010805","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005423","name":"Akademiska Sjukhuset","doi-asserted-by":"publisher","award":["ALF 1040530\/2019","ALF\u2010937815\/2020"],"award-info":[{"award-number":["ALF 1040530\/2019","ALF\u2010937815\/2020"]}],"id":[{"id":"10.13039\/501100005423","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Single motherhood by choice has been associated with increased perinatal risks and poorer psychological well\u2010being for the families. However, limited evidence exists regarding the health status of these women before, during, and after pregnancy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and Methods<\/jats:title>\n                    <jats:p>\n                      This prospective multiregistry study was conducted in Sweden and included unpartnered women conceiving with the help of assisted conception (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009296) and all partnered women conceiving through IVF with the couple's own gametes (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20097294), giving birth during 2007\u20132014. The primary outcomes assessed maternal somatic and mental health diagnoses 3\u2009years before and after pregnancy, while secondary outcomes examined obstetric and neonatal complications. Data were retrieved from Swedish population\u2010based registers, capturing ICD\u201010 diagnoses, filled prescriptions of psychiatric medications, and manually recorded perinatal data. Crude and adjusted logistic regression analyses were performed.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Single mothers through assisted conception were older and had significantly higher rates of smoking and obesity compared to partnered women. They also had a higher prevalence of psychiatric diagnoses, including anxiety and depression, both before (14.2% vs. 4.3%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and after childbirth (29.1 vs. 12.1%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Psychiatric medication use was significantly higher among single mothers both before (34.1% vs. 13.8%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and after pregnancy (34.5% vs. 15.0%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Obstetric and neonatal outcomes, including preterm birth and low birth weight, showed no significant differences between the groups, except for a higher incidence of multiple births among single mothers. The index population had a twofold increased risk of psychiatric conditions or medications, despite adjustment, in the period immediately before [aOR 2.51 (1.92\u20133.27)] or after childbirth [aOR 2.00 (1.51\u20132.66)].\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The study reveals that single mothers through assisted conception face increased psychiatric risks before and after childbirth compared to partnered women undergoing autologous IVF. The findings highlight the need for careful eligibility assessment by healthcare professionals and underscore the importance of ensuring a robust support system to help these mothers manage the challenges of solo parenthood.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/aogs.70037","type":"journal-article","created":{"date-parts":[[2025,8,15]],"date-time":"2025-08-15T03:33:51Z","timestamp":1755228831000},"page":"2078-2092","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Perinatal outcomes and maternal health before and after single motherhood through assisted conception: A multiregistry study in Sweden"],"prefix":"10.1111","volume":"104","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2253-4682","authenticated-orcid":false,"given":"Evangelia","family":"Elenis","sequence":"first","affiliation":[{"name":"Department of Women's and Children's Health Uppsala University  Uppsala Sweden"},{"name":"Reproduction Center, Women's Clinic Uppsala University Hospital  Uppsala Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cecilia Mitt","family":"Holm","sequence":"additional","affiliation":[{"name":"Department of Women's and Children's Health Uppsala University  Uppsala Sweden"},{"name":"Centre for Clinical Research S\u00f6rmland Uppsala University  Eskilstuna Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ove","family":"Axelsson","sequence":"additional","affiliation":[{"name":"Department of Women's and Children's Health Uppsala University  Uppsala Sweden"},{"name":"Centre for Clinical Research S\u00f6rmland Uppsala University  Eskilstuna Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Agneta Skoog","family":"Svanberg","sequence":"additional","affiliation":[{"name":"Department of Women's and Children's Health Uppsala University  Uppsala Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudia","family":"Lampic","sequence":"additional","affiliation":[{"name":"Department of Psychology Ume\u00e5 University  Ume\u00e5 Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gunilla","family":"Sydsj\u00f6","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, and Department of Biomedical and Clinical Sciences Link\u00f6ping University  Link\u00f6ping Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,8,14]]},"reference":[{"key":"e_1_2_14_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2393-14-86"},{"key":"e_1_2_14_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/dei367"},{"key":"e_1_2_14_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/1403494815576269"},{"key":"e_1_2_14_5_1","doi-asserted-by":"publisher","DOI":"10.1080\/08952833.2022.2136832"},{"volume-title":"Family formations in fertility treatment 2022","year":"2024","author":"HFEA","key":"e_1_2_14_6_1"},{"key":"e_1_2_14_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.alcr.2022.100496"},{"key":"e_1_2_14_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10680-020-09571-z"},{"key":"e_1_2_14_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10964-016-0607-y"},{"issue":"3","key":"e_1_2_14_10_1","doi-asserted-by":"crossref","first-page":"1184","DOI":"10.2307\/2580615","article-title":"Growing up with a single parent: what hurts, what helps","volume":"73","author":"Parcel TL","year":"1995","journal-title":"Soc Forces"},{"key":"e_1_2_14_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurpub\/cks062"},{"issue":"5","key":"e_1_2_14_12_1","first-page":"709","article-title":"Comparisons of the influence of raising people's identity on mental health between two\u2010parents family children and single parent family children by propensity score matching","volume":"46","author":"Wang D","year":"2017","journal-title":"J Hyg Res"},{"key":"e_1_2_14_13_1","doi-asserted-by":"publisher","DOI":"10.3390\/healthcare11131828"},{"key":"e_1_2_14_14_1","doi-asserted-by":"publisher","DOI":"10.15288\/jsad.2017.78.745"},{"key":"e_1_2_14_15_1","doi-asserted-by":"publisher","DOI":"10.2307\/2657556"},{"key":"e_1_2_14_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/aogs.12619"},{"key":"e_1_2_14_17_1","doi-asserted-by":"publisher","DOI":"10.1136\/jech-2014-205149"},{"key":"e_1_2_14_18_1","doi-asserted-by":"crossref","unstructured":"GrahamS.Choosing single motherhood? Single women negotiating the nuclear family ideal.2012.","DOI":"10.5040\/9781780930114.ch-007"},{"key":"e_1_2_14_19_1","first-page":"1","article-title":"Being a 'good' parent: single women reflecting upon \u2018selfishness\u2019 and \u2018risk\u2019 when pursuing motherhood through sperm donation","volume":"20","author":"Graham S","year":"2017","journal-title":"Anthropol Med"},{"key":"e_1_2_14_20_1","doi-asserted-by":"publisher","DOI":"10.3109\/14647270903373867"},{"key":"e_1_2_14_21_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/deh823"},{"key":"e_1_2_14_22_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/dem250"},{"key":"e_1_2_14_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/9781118963418.childpsy102"},{"key":"e_1_2_14_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2020.08.678"},{"key":"e_1_2_14_25_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12884-019-2239-1"},{"key":"e_1_2_14_26_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2014-005840"},{"key":"e_1_2_14_27_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12884-015-0687-9"},{"key":"e_1_2_14_28_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12887-016-0708-5"},{"key":"e_1_2_14_29_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00737-007-0185-9"},{"key":"e_1_2_14_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ssresearch.2015.08.009"},{"key":"e_1_2_14_31_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10995-012-0985-z"},{"key":"e_1_2_14_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.adolescence.2006.08.001"},{"key":"e_1_2_14_33_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12912-016-0134-x"},{"key":"e_1_2_14_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ssresearch.2010.03.002"},{"volume-title":"Skal enslige kvinner f\u00e5 rett til assistert befruktning? [Will single women gain the right to assisted reproduction?]","year":"2020","author":"Bioteknologir\u00e5det","key":"e_1_2_14_35_1"},{"volume-title":"Utredningar","year":"2017","author":"SOU","key":"e_1_2_14_36_1"},{"key":"e_1_2_14_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rbms.2016.09.001"},{"volume-title":"The latest version of the National Board of Health and Welfare's regulations and general advice (SOSFS 2009:32) on the use of tissues and cells in healthcare and clinical research is available on the National Board of Health and Welfare's website [Senaste version av SOSFS 2009:32 Socialstyrelsens f\u00f6reskrifter och allm\u00e4nna r\u00e5d om anv\u00e4ndning av v\u00e4vnader och celler i h\u00e4lso\u2010 och sjukv\u00e5rden och vid klinisk forskning m.m.]","year":"2019","author":"Socialstyrelsen","key":"e_1_2_14_38_1"},{"key":"e_1_2_14_39_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2020-041538"},{"volume-title":"National report 2024. Refers to treatments started","year":"2022","author":"Q\u2010IVF","key":"e_1_2_14_40_1"},{"key":"e_1_2_14_41_1","doi-asserted-by":"publisher","DOI":"10.2147\/JMDH.S229807"},{"key":"e_1_2_14_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.srhc.2017.03.001"},{"key":"e_1_2_14_43_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40738-020-00078-z"},{"key":"e_1_2_14_44_1","doi-asserted-by":"publisher","DOI":"10.1037\/0002-9432.75.2.242"},{"key":"e_1_2_14_45_1","doi-asserted-by":"publisher","DOI":"10.1037\/fam0000797"},{"key":"e_1_2_14_46_1","doi-asserted-by":"publisher","DOI":"10.1037\/fam0000188"},{"volume-title":"Maternal Health Care, Sexual and Reproductive Health [M\u00f6drah\u00e4lsov\u00e5rd, Sexuell Och Reproduktiv H\u00e4lsa]","year":"2016","author":"SFOG SSoOaG","key":"e_1_2_14_47_1"},{"key":"e_1_2_14_48_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10654-009-9350-y"},{"key":"e_1_2_14_49_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2458-11-450"},{"volume-title":"Obstetric ultrasound [Obstetrisk Ultraljud]","year":"2014","author":"SFOG SSoOaG","key":"e_1_2_14_50_1"},{"key":"e_1_2_14_51_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.1996.tb14164.x"},{"key":"e_1_2_14_52_1","first-page":"64","article-title":"Single motherhood by choice in Sweden:unanticipated support needs and financial problems","volume":"102","author":"Af Sandeberg Y","year":"2023","journal-title":"Acta Obstet Gynecol Scand"},{"key":"e_1_2_14_53_1","doi-asserted-by":"publisher","DOI":"10.1037\/fam0000680"},{"key":"e_1_2_14_54_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-0025.2012.01187.x"},{"key":"e_1_2_14_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2007.07.1296"},{"key":"e_1_2_14_56_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/deh744"},{"key":"e_1_2_14_57_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajo.12260"},{"key":"e_1_2_14_58_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm12072571"},{"key":"e_1_2_14_59_1","unstructured":"Assisted Reproduction: Data and analyses [Assisteret reproduktion: tal og analyse].2012\u20132023https:\/\/www.esundhed.dk\/Emner\/Graviditet\u2010foedsler\u2010og\u2010boern\/Assisteret\u2010reproduktion\u2010IVF#tabpanel428E0E88BB504C4BB84679261E1BE43F. Accessed 6 February 2025."},{"volume-title":"Statistics on mental health in Sweden[Statistik om psykisk h\u00e4lsa i Sverige]","year":"2024","author":"Folkh\u00e4lsomyndigheten TPHAoS","key":"e_1_2_14_60_1"},{"key":"e_1_2_14_61_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12888-020-02749-z"},{"key":"e_1_2_14_62_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00127-022-02371-2"},{"key":"e_1_2_14_63_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12888-019-2082-y"},{"key":"e_1_2_14_64_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10815-022-02402-6"},{"issue":"3","key":"e_1_2_14_65_1","first-page":"199","article-title":"Postpartum psychological pressure on single mothers: an interpretative phenomenological analysis","volume":"3","author":"Vic B","year":"2020","journal-title":"J Humanit Appl Soc Sci"},{"key":"e_1_2_14_66_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12887-021-03103-2"},{"volume-title":"Bekendtg\u00f8relse Af Lov Om Kunstig Befrugtning i Forbindelse Med L\u00e6gelig behandling, Diagnostik Og Forskning m.v. [Promulgation of the Law On Artificial Insemination in Connection With Medical treatment, Diagnostics and research, etc.]","year":"2006","author":"Elderly MoHaT","key":"e_1_2_14_67_1"},{"volume-title":"Lov om \u00e6ndring af lov om assisteret reproduktion i forbindelse med behandling, diagnostik og forskning m.v. og sundhedsloven [act on the amendment of the act on assisted reproduction in connection with treatment, diagnosis, and research, etc., and the health act]","year":"2017","author":"Elderly MoHat","key":"e_1_2_14_68_1"}],"container-title":["Acta Obstetricia et Gynecologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aogs.70037","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T07:03:56Z","timestamp":1761894236000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/aogs.70037"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,14]]},"references-count":67,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2025,11]]}},"alternative-id":["10.1111\/aogs.70037"],"URL":"https:\/\/doi.org\/10.1111\/aogs.70037","archive":["Portico"],"relation":{},"ISSN":["0001-6349","1600-0412"],"issn-type":[{"type":"print","value":"0001-6349"},{"type":"electronic","value":"1600-0412"}],"subject":[],"published":{"date-parts":[[2025,8,14]]},"assertion":[{"value":"2025-04-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-30","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-08-14","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}