{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T08:49:56Z","timestamp":1792226996720,"version":"4.4.0"},"reference-count":31,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T00:00:00Z","timestamp":1759881600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2025,12]]},"abstract":"Abstract<\/jats:title>\n \n Introduction<\/jats:title>\n The healthcare reorganization during the COVID\u201019 pandemic affected colposcopy services and cervical cancer prevention, particularly in those countries where healthcare systems were already under\u2010resourced. This review aimed to quantify the reduction in colposcopy services across countries during the COVID\u201019 pandemic and to determine whether the data source per study and cervical cancer screening coverage per country influenced the extent of these reductions.<\/jats:p>\n <\/jats:sec>\n \n Material and Methods<\/jats:title>\n \n Studies reporting comparative data on colposcopy services between the COVID\u201019 pre\u2010pandemic and pandemic period were included. MEDLINE, Embase, EMCare, Covid\u201019 Research, British Nursing Index, APA PsycINFO, and Allied and Complimentary Medicine databases were searched for studies published from March 2020 to December 2023. The Newcastle\u2212Ottawa scale was used for risk of bias assessment. The number of colposcopies, cervical treatments, pre\u2010invasive lesions diagnoses, and cervical cancer diagnoses per month were compared between the pre\u2010pandemic (before March 2020) and pandemic period (after March 2020). The effect measure was the standardized mean difference. Heterogeneity was evaluated with the chi\u2010squared test and quantified with the\n I<\/jats:italic>\n 2<\/jats:sup>\n method. A meta\u2010regression was performed, considering the data source (regional\/national databases\/registries or institutional databases) and the screening coverage according to World Health Organization data (\u226570% or <70%) as moderators. The review was registered on PROSPERO (CRD42023447188).\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Thirteen studies were included. Twelve were of good\/high quality according to the Newcastle\u2212Ottawa scale. The standardized mean difference between the pre\u2010pandemic and pandemic periods was \u22121.60 (95% CI \u22122.49 to \u22120.72,\n p<\/jats:italic>\n \u2009=\u20090.004) for colposcopies (4 studies,\n I<\/jats:italic>\n 2<\/jats:sup>\n \u2009=\u200960.97%,\n p<\/jats:italic>\n \u2009=\u20090.075), \u22121.70 (95% CI \u22122.50 to \u22120.90,\n p<\/jats:italic>\n \u2009<\u20090.001) for cervical treatments (5 studies,\n I<\/jats:italic>\n 2<\/jats:sup>\n \u2009=\u200952.92%,\n p<\/jats:italic>\n \u2009=\u20090.081), \u22124.61 (95% CI \u20107.90 to \u22121.33,\n p<\/jats:italic>\n \u2009=\u20090.006) for pre\u2010invasive lesion diagnoses (4 studies,\n I<\/jats:italic>\n 2<\/jats:sup>\n \u2009=\u200992.45%, p\u2009<\u20090.001), and \u22120.85\u2009(95% CI \u22121.52 to \u22120.19,\n p<\/jats:italic>\n \u2009=\u20090.012) for cervical cancer diagnoses (9 studies,\n I<\/jats:italic>\n 2<\/jats:sup>\n \u2009=\u200971.07%,\n p<\/jats:italic>\n \u2009=\u20090.002). At meta\u2010regression, further reductions for cervical treatments and pre\u2010invasive lesion diagnoses were observed in the case of screening coverage <70%.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n During the COVID\u201019 pandemic, a reduction in colposcopies, cervical treatments, pre\u2010invasive lesions diagnoses, and invasive cancer diagnoses was observed. Since a screening coverage of <70% heightened these declines, increasing such coverage could lead to better resilience of cervical cancer prevention services to future crises.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/aogs.70066","type":"journal-article","created":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T07:21:45Z","timestamp":1759908105000},"page":"2215-2225","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["The effect of healthcare disruptions during the\n COVID<\/scp>\n \u201019 pandemic on colposcopy services and practice: A systematic review and meta\u2010analysis"],"prefix":"10.1111","volume":"104","author":[{"given":"Giovanni","family":"Delli Carpini","sequence":"first","affiliation":[{"name":"Gynecologic Section, Department of Odontostomatologic and Specialized Clinical Sciences Universit\u00e0 Politecnica Delle Marche Ancona Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zahid","family":"Mammadov","sequence":"additional","affiliation":[{"name":"Northern Gynaecological Oncology Centre Queen Elizabeth Hospital Gateshead UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon","family":"Leeson","sequence":"additional","affiliation":[{"name":"European Federation for Colposcopy, Triumph Benelux Brussels Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4616-9827","authenticated-orcid":false,"given":"Anne","family":"Hammer","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine Aarhus University Aarhus Denmark"},{"name":"Department of Obstetrics and Gynecology, G\u00f8dstrup Hospital University Clinic for HPV\u2010Related Gynecological Disease Herning Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mihaela","family":"Grigore","sequence":"additional","affiliation":[{"name":"Department Obstetrics and Gynecology University of Medicine and Pharmacy \u201cGrigore T. Popa\u201d Iasi Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Ciavattini","sequence":"additional","affiliation":[{"name":"Gynecologic Section, Department of Odontostomatologic and Specialized Clinical Sciences Universit\u00e0 Politecnica Delle Marche Ancona Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,10,8]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics12040907"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ypmed.2021.106586"},{"key":"e_1_2_13_4_1","first-page":"570","article-title":"The initial impact of the COVID\u201019 pandemic on the diagnosis of new cancers at a large pathology laboratory in the public health sector, Western Cape Province, South Africa [published correction appears in S Afr Med J. 2021;111:13325.]","volume":"111","author":"Van Wyk AC","year":"2021","journal-title":"S Afr Med J"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.16741"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/cyt.13091"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.17061\/phrp3042026"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/LGT.0000000000000677"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/cam4.4655"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lanepe.2021.100101"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.3802\/jgo.2023.34.e7"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/CEJ.0000000000000686"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ypmed.2022.107264"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n71"},{"key":"e_1_2_13_15_1","unstructured":"WellsGA SheaB PetersonJ et\u00a0al.The Newcastle\u2010Ottawa scale (NOS) for assessing the quality of nonrandomised studies in meta\u2010analyses. 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