{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:44:22Z","timestamp":1787013862391,"version":"build-2736575974"},"reference-count":41,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T00:00:00Z","timestamp":1760054400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004785","name":"NordForsk","doi-asserted-by":"publisher","award":["135876"],"award-info":[{"award-number":["135876"]}],"id":[{"id":"10.13039\/501100004785","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005416","name":"Norges Forskningsr\u00e5d","doi-asserted-by":"publisher","award":["324312"],"award-info":[{"award-number":["324312"]}],"id":[{"id":"10.13039\/501100005416","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005416","name":"Norges Forskningsr\u00e5d","doi-asserted-by":"publisher","award":["262700"],"award-info":[{"award-number":["262700"]}],"id":[{"id":"10.13039\/501100005416","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>The aim was to evaluate whether SARS\u2010CoV\u20102 infection during pregnancy was associated with severe postpartum hemorrhage (PPH), as SARS\u2010CoV\u20102 infection has been shown to affect the coagulation system.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and Methods<\/jats:title>\n                    <jats:p>In this national register\u2010based cohort study in Sweden, Denmark, and Norway, we studied the association between severe PPH according to a registered positive test for SARS\u2010CoV\u20102 during pregnancy between March 1, 2020 and March 31, 2023 using logistic regression analyses to estimate odds ratios (ORs) with 95% confidence intervals (CI). Country\u2010specific estimates of association were combined in random effects meta\u2010analyses. The primary outcome was severe PPH, defined as a blood loss &gt;1500\u2009mL and\/or receiving a blood transfusion.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We included 542\u2009394 singleton deliveries (264\u2009804 in Sweden, 143\u2009775 in Denmark, and 133\u2009815 in Norway), of which 62\u2009606 women (11%) had a positive SARS\u2010CoV\u20102 test during pregnancy, and 20\u2009786 (3.8%) deliveries were registered with a severe PPH. Overall, we observed no association between testing positive for SARS\u2010CoV\u20102 during pregnancy and severe PPH (combined adjusted OR 1.04; 95% CI: 0.96\u20131.12). The results were similar for different calendar periods corresponding to dominant SARS\u2010CoV\u20102 variants. We did, however, observe an association between severe PPH and women testing positive within 7\u2009days before delivery (combined adjusted OR 1.30; 95% CI: 1.10\u20131.53).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>There was no association identified between SARS\u2010CoV\u20102 test positivity and PPH of &gt;1500\u2009mL and\/or blood transfusion in pregnant women from three Scandinavian countries. However, we observed a 30% higher odds of severe PPH among pregnant women who tested positive within one week before delivery.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/aogs.70069","type":"journal-article","created":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T03:49:28Z","timestamp":1760154568000},"page":"2355-2365","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Postpartum hemorrhage after\n                    <scp>SARS<\/scp>\n                    \u2010\n                    <scp>CoV<\/scp>\n                    \u20102 infection in pregnancy: A Scandinavian register\u2010based cohort study"],"prefix":"10.1111","volume":"104","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4148-9765","authenticated-orcid":false,"given":"Trine Damsted","family":"Rasmussen","sequence":"first","affiliation":[{"name":"Section of Epidemiology, Department of Public Health University of Copenhagen  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2069-9723","authenticated-orcid":false,"given":"Stine Kjaer","family":"Urhoj","sequence":"additional","affiliation":[{"name":"Section of Epidemiology, Department of Public Health University of Copenhagen  Copenhagen Denmark"},{"name":"Statistics Denmark  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria C.","family":"Magnus","sequence":"additional","affiliation":[{"name":"Centre for Fertility and Health Norwegian Institute of Public Health  Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonas","family":"S\u00f6derling","sequence":"additional","affiliation":[{"name":"Clinical Epidemiology Division, Department of Medicine, Solna Karolinska Institutet  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4697-4316","authenticated-orcid":false,"given":"Laura L.","family":"Oakley","sequence":"additional","affiliation":[{"name":"Centre for Fertility and Health Norwegian Institute of Public Health  Oslo Norway"},{"name":"Department of Non\u2010Communicable Disease Epidemiology London School of Hygiene and Tropical Medicine  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9019-9233","authenticated-orcid":false,"given":"Anne K.","family":"\u00d6rtqvist","sequence":"additional","affiliation":[{"name":"Clinical Epidemiology Division, Department of Medicine, Solna Karolinska Institutet  Stockholm Sweden"},{"name":"Department of Obstetrics and Gynecology Visby County Hospital  Visby Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hellen M.","family":"Edwards","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology University Hospital Herlev  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lone","family":"Krebs","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Amager and Hvidovre Hospital  Copenhagen Denmark"},{"name":"Institute of Clinical Medicine University of Copenhagen  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hilde M.","family":"Engjom","sequence":"additional","affiliation":[{"name":"Department of Health Registry Research and Development Norwegian Institute of Public Health  Bergen Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1528-4563","authenticated-orcid":false,"given":"Olof","family":"Stephansson","sequence":"additional","affiliation":[{"name":"Clinical Epidemiology Division, Department of Medicine, Solna Karolinska Institutet  Stockholm Sweden"},{"name":"Department of Women's Health Karolinska University Hospital  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siri E.","family":"H\u00e5berg","sequence":"additional","affiliation":[{"name":"Centre for Fertility and Health Norwegian Institute of Public Health  Oslo Norway"},{"name":"Department of Global Public Health and Primary Care University of Bergen  Bergen Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne\u2010Marie Nybo","family":"Andersen","sequence":"additional","affiliation":[{"name":"Section of Epidemiology, Department of Public Health University of Copenhagen  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna J. 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