{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T03:51:49Z","timestamp":1785556309624,"version":"3.56.0"},"reference-count":28,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T00:00:00Z","timestamp":1761436800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100009780","name":"Region Sk\u00e5ne","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100009780","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2025,12]]},"abstract":"Abstract<\/jats:title>\n \n Introduction<\/jats:title>\n \n This multicenter, prospective observational study aimed to evaluate the performance of the StatStrip\n \u00ae<\/jats:sup>\n Lactate 2 (Nova Biomedical, Waltham, US) point\u2010of\u2010care device for fetal blood lactate measurement and to determine the corresponding lactate value equivalent to the established intervention cutoff used with the outgoing StatStrip\n \u00ae<\/jats:sup>\n Lactate device.\n <\/jats:p>\n <\/jats:sec>\n \n Material and Methods<\/jats:title>\n \n The study was conducted from August 2024 to February 2025 at two maternity clinics in Sweden and one in Denmark. It included women with singleton pregnancies (\u226535\u2009+\u20090\u2009weeks) undergoing fetal blood sampling due to non\u2010reassuring intrapartal fetal heart rate patterns during labor. Fetal scalp blood sampling (FBS) lactate concentrations were measured using both StatStrip\n \u00ae<\/jats:sup>\n Lactate and StatStrip\n \u00ae<\/jats:sup>\n Lactate2. The first StatStrip\n \u00ae<\/jats:sup>\n Lactate measurement guided clinical decisions, while subsequent StatStrip\n \u00ae<\/jats:sup>\n Lactate2 measurements were recorded for validation and establishment of a conversion equation by linear regression. Additionally, arterial and venous umbilical cord blood samples were analyzed by both ABL 800 (Radiometer, Denmark) and StatStrip\n \u00ae<\/jats:sup>\n Lactate2 for validation.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Blood samples from 349 fetuses were included, with 549 parallel FBS lactate samples. StatStrip\n \u00ae<\/jats:sup>\n Lactate2 concentrations correlated with StatStrip\n \u00ae<\/jats:sup>\n Lactate (\n r<\/jats:italic>\n \u2009=\u20090.94;\n p<\/jats:italic>\n \u2009\u2264\u20090.001). A conversion equation was retrieved: StatStrip\n \u00ae<\/jats:sup>\n Lactate2\u2009=\u2009(1.4\u2009\u00d7\u2009StatStrip\n \u00ae<\/jats:sup>\n Lactate) \u2212 0.28. From 37 paired umbilical cord blood samples, the correlation between lactate concentrations by StatStrip\n \u00ae<\/jats:sup>\n Lactate2 and ABL800 was\n r<\/jats:italic>\n \u2009=\u20090.99 (\n p<\/jats:italic>\n \u2009\u2264\u20090.001) in arterial blood and r\u2009=\u20090.98 (\n p<\/jats:italic>\n \u2009\u2264\u20090.001) in venous blood. Mean coefficients of variation for lactate concentrations >3.0\u2009mmol\/L were 8.2% in fetal scalp blood and 3.8% in umbilical cord blood.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n A fetal blood lactate concentration \u22657.0\u2009mmol\/L measured by StatStrip\n \u00ae<\/jats:sup>\n Lactate2 corresponds to the established intervention cutoff lactate value \u22655.2\u2009mmol\/L measured by StatStrip\n \u00ae<\/jats:sup>\n Lactate. Precision was acceptable but may be improved by using the mean of two measurements, particularly when the first result falls between 6.0 and 8.0\u2009mmol\/L. We also recommend ensuring the correct sampling techniques to minimize preanalytical variation.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/aogs.70080","type":"journal-article","created":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T05:05:36Z","timestamp":1761541536000},"page":"2273-2281","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Validation and proposal of a clinical intervention cutoff in fetal scalp blood for the point\u2010of care\u2010lactate meter\n StatStrip<\/scp>\n \u00ae<\/sup>\n 2"],"prefix":"10.1111","volume":"104","author":[{"given":"Sofie","family":"Gellert","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Zealand University Hospital Roskilde Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Norrestam","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Helsingborg Hospital Helsingborg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra","family":"Tidstedt","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology H\u00f6glandssjukhuset Eksj\u00f6 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claes","family":"Ignell","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Helsingborg Hospital Helsingborg Sweden"},{"name":"Department of Clinical Sciences Lund Lund University Lund Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Per\u2010Erik","family":"Isberg","sequence":"additional","affiliation":[{"name":"Department of Statistics Lund University Lund Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9032-5428","authenticated-orcid":false,"given":"Nana","family":"Wiberg","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences Malm\u00f6 Lund University Lund Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5840-4062","authenticated-orcid":false,"given":"Linda","family":"Iorizzo","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences Lund Lund University Lund Sweden"},{"name":"Department of Obstetrics and Gynecology Sk\u00e5ne University Hospital Lund Lund Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,10,26]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2015.06.021"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/aogs.12421"},{"issue":"5","key":"e_1_2_13_4_1","first-page":"194","article-title":"Foetal scalp blood sampling: impact on the incidence of caesarean section and assisted vaginal deliveries for non\u2010reassuring foetal heart rate and its use according to gestational age","volume":"215","author":"Reif P","year":"2011","journal-title":"Z Geburtshilfe Neonatol"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1515\/JPM.2006.093"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006254-198708000-00007"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-022-06649-3"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.39553.406991.25"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/aogs.14140"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinbiochem.2018.03.006"},{"issue":"1","key":"e_1_2_13_11_1","first-page":"203","article-title":"Reliability and accuracy of six hand\u2010held blood lactate analysers","volume":"14","author":"Bonaventura JM","year":"2014","journal-title":"J Sports Sci Med"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2008-2654"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/clinchem\/38.12.2430"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajo.12671"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cca.2019.04.003"},{"key":"e_1_2_13_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/aogs.13078"},{"key":"e_1_2_13_17_1","doi-asserted-by":"publisher","DOI":"10.1515\/cclm-2013-0732"},{"key":"e_1_2_13_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.16924"},{"key":"e_1_2_13_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/aogs.15140"},{"key":"e_1_2_13_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.plabm.2024.e00375"},{"key":"e_1_2_13_21_1","unstructured":"SFOG\/L\u00d6F.CTG utbildning [Internet]. 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