{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T11:23:30Z","timestamp":1775301810715,"version":"3.50.1"},"reference-count":40,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T00:00:00Z","timestamp":1771891200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T00:00:00Z","timestamp":1771891200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Gestational diabetes mellitus (GDM) is associated with adverse outcomes in both pregnancy and the postpartum period. Although placental pathology has been extensively studied in relation to neonatal complications, its relevance to maternal health after delivery remains less well defined. This study aimed to compare gross and histologic placental features between GDM and normoglycemic pregnancies according to the Amsterdam Placental Workshop Group Consensus Statement. It also evaluated associations between specific placental lesions and both neonatal outcomes and maternal dysglycemia at 6\u2009weeks postpartum in the GDM cohort.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and Methods<\/jats:title>\n                    <jats:p>This prospective observational cohort study included 200 women with GDM and 100 normoglycemic women who delivered at term. Placental examination comprised gross and histologic evaluation of lesions classified according to the Amsterdam criteria, including maternal and fetal vascular malperfusion, as well as commonly reported non\u2010classified lesions such as chorangiosis and delayed villous maturation (DVM). Neonatal outcomes assessed were large\u2010for\u2010gestational\u2010age status, low 1\u2010min Apgar scores (&lt;7), and neonatal hypoglycemia. Postpartum maternal dysglycemia at 6\u2009weeks was assessed using a 75\u2010g, 2\u2010h oral glucose tolerance test and classified as prediabetes or type 2 diabetes mellitus. Associations were evaluated using logistic regression analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Placental lesions were significantly more common in GDM than in normoglycemic pregnancies. These included maternal vascular malperfusion (67.5% vs. 39.0%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), fetal vascular malperfusion (49.0% vs. 22.0%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), chorangiosis (51.0% vs. 11.0%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), and DVM (17.0% vs. 8.0%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.034). DVM was independently associated with large\u2010for\u2010gestational\u2010age infants (adjusted odds ratio [aOR]\u2009=\u20092.54, 95% confidence interval [CI]\u2009=\u20091.03\u20136.24) and low 1\u2010min Apgar scores (aOR\u2009=\u20094.59, 95% CI\u2009=\u20091.08\u201319.63). Chorangiosis was independently associated with maternal dysglycemia at 6\u2009weeks postpartum (aOR\u2009=\u20092.33, 95% CI\u2009=\u20091.07\u20135.07), an association primarily driven by prediabetes (aOR\u2009=\u20092.74, 95% CI\u2009=\u20091.22\u20136.15). Gross placental measurements did not differ significantly between groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>GDM is associated with various placental abnormalities, including Amsterdam\u2010classified and non\u2010classified lesions. DVM was associated with adverse neonatal outcomes, whereas chorangiosis was associated with postpartum dysglycemia. Systematic placental examination may aid in identifying women at risk of future metabolic disease.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/aogs.70174","type":"journal-article","created":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T15:33:07Z","timestamp":1772983987000},"page":"714-723","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Placental pathology in gestational diabetes mellitus: Associations with neonatal outcomes and postpartum dysglycemia"],"prefix":"10.1111","volume":"105","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-5628-010X","authenticated-orcid":false,"given":"Chutima","family":"Chavanisakun","sequence":"first","affiliation":[{"name":"Department of Anatomical Pathology, Faculty of Medicine Vajira Hospital Navamindradhiraj University  Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5367-8884","authenticated-orcid":false,"given":"Siriwan","family":"Tangjitgamol","sequence":"additional","affiliation":[{"name":"Women's Health Center MedPark Hospital  Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0925-2613","authenticated-orcid":false,"given":"Chadakarn","family":"Phaloprakarn","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Faculty of Medicine Vajira Hospital Navamindradhiraj University  Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,2,24]]},"reference":[{"key":"e_1_2_14_2_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc22-S002"},{"key":"e_1_2_14_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2021.04.005"},{"key":"e_1_2_14_4_1","doi-asserted-by":"publisher","DOI":"10.4103\/JLP.JLP_148_16"},{"key":"e_1_2_14_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2025.02.008"},{"key":"e_1_2_14_6_1","doi-asserted-by":"publisher","DOI":"10.5858\/arpa.2015-0225-CC"},{"key":"e_1_2_14_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41379-021-00747-4"},{"key":"e_1_2_14_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/jog.15046"},{"key":"e_1_2_14_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2024.01.012"},{"key":"e_1_2_14_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2016.11.004"},{"key":"e_1_2_14_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/aogs.70064"},{"key":"e_1_2_14_12_1","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.121.18394"},{"key":"e_1_2_14_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/aogs.70073"},{"key":"e_1_2_14_14_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2025-104482"},{"key":"e_1_2_14_15_1","doi-asserted-by":"publisher","DOI":"10.35755\/jmedassocthai.2025.6.464-469-02420"},{"key":"e_1_2_14_16_1","doi-asserted-by":"publisher","DOI":"10.1080\/00016340801908783"},{"key":"e_1_2_14_17_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12884-021-03576-0"},{"issue":"8","key":"e_1_2_14_18_1","first-page":"798","article-title":"Standard intrauterine growth curve of Thai neonates delivered at Rajavithi hospital","volume":"97","author":"Borisut P","year":"2014","journal-title":"J Med Assoc Thai"},{"key":"e_1_2_14_19_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2010-3851"},{"key":"e_1_2_14_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabres.2025.112336"},{"key":"e_1_2_14_21_1","doi-asserted-by":"publisher","DOI":"10.3390\/healthcare11091315"},{"key":"e_1_2_14_22_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms19113665"},{"key":"e_1_2_14_23_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms252212195"},{"key":"e_1_2_14_24_1","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/145846"},{"issue":"9","key":"e_1_2_14_25_1","first-page":"1241","article-title":"Impaired gestational glucose tolerance. 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