{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T03:08:10Z","timestamp":1792292890058,"version":"4.4.0"},"reference-count":26,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T00:00:00Z","timestamp":1779667200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T00:00:00Z","timestamp":1779667200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100003123","name":"Fetal Medicine Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003123","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100011033","name":"Thermo Fisher Scientific","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100011033","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Pre\u2010eclampsia (PE) remains a major complication of pregnancies, globally, and while there is no intervention proven to be effective in decreasing late preterm and term PE; the PREVENT\u2010PE trial aimed to evaluate whether the intervention\u2014a strategy of screening for PE risk at 35\u201336\u2009weeks' gestation, and for a risk of \u22651\u2010in\u201050, offering risk\u2010stratified, planned early term birth\u2014could reduce the incidence of subsequent PE, compared with usual care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and Methods<\/jats:title>\n                    <jats:p>We aimed to evaluate the acceptability of trial participation and risk communication for women participating in The PREVENT\u2010PE trial [ISRCTN41632964] in the United Kingdom. From March to October 2024, trial participants were invited, antenatally and\/or postnatally, to complete an online survey, and acceptability and risk communication measures were compared by trial arm.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of those accessing the survey, 257 out of 478 (48.2%) were antenatal (median 35.4\u2009weeks' gestation), and 485 out of 1617 (30.0%) were postnatal (median 25.6\u2009weeks postnatally) respondents who were eligible. Antenatally, and by trial arm: (i) most women felt: comfortable with the trial (&gt;70%); participation required little\/no effort (&gt;75%; 77.9% [intervention] vs. 91.7% [control],\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.05); confident in participation (&gt;75%); the trial was acceptable (\u224890%); and PE risk screening was fair (&gt;90%), could reduce chances of becoming seriously ill (&gt;90%), and understood how that could be achieved (&gt;90%); (ii) half disagreed that timed birth for PE would interfere with competing priorities, although 20\u201330% agreed; (iii) \u226580% of participants felt listened to, were able to ask questions and receive helpful answers, had their preferences considered, had clear on the situation being discussed, and were confident about their decision; and (iv) \u224850% were uncertain about what was going to happen. Postnatally, views were more neutral, without an increase in negativity.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Findings indicate that women find third\u2010trimester screening for PE and risk\u2010stratified planned early term birth highly acceptable, understand those risks, and the potential to favorably impact their pregnancy outcome.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/aogs.70230","type":"journal-article","created":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T05:00:47Z","timestamp":1779771647000},"page":"1553-1565","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Pre\u2010eclampsia risk\u2010stratified planned birth at term: A survey of women\u2019s perspectives on acceptability and risk communication"],"prefix":"10.1111","volume":"105","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5381-1670","authenticated-orcid":false,"given":"James","family":"Goadsby","sequence":"first","affiliation":[{"name":"Harris Birthright Research Centre for Fetal Medicine King\u2019s College Hospital  London UK"},{"name":"Department of Women &amp; Children\u2019s Health, School of Life Course &amp; Population Health Sciences King\u2019s College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-3391-5380","authenticated-orcid":false,"given":"Angel","family":"Leung","sequence":"additional","affiliation":[{"name":"Harris Birthright Research Centre for Fetal Medicine King\u2019s College Hospital  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7177-3471","authenticated-orcid":false,"given":"Sergio A.","family":"Silverio","sequence":"additional","affiliation":[{"name":"Department of Women &amp; Children\u2019s Health, School of Life Course &amp; Population Health Sciences King\u2019s College London  London UK"},{"name":"Department of Psychology, Institute of Population Health University of Liverpool  Liverpool UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1355-610X","authenticated-orcid":false,"given":"Laura A.","family":"Magee","sequence":"additional","affiliation":[{"name":"Department of Women &amp; Children\u2019s Health, School of Life Course &amp; Population Health Sciences King\u2019s College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4136-3070","authenticated-orcid":false,"given":"Peter","family":"von Dadelszen","sequence":"additional","affiliation":[{"name":"Department of Women &amp; Children\u2019s Health, School of Life Course &amp; Population Health Sciences King\u2019s College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5856-6072","authenticated-orcid":false,"given":"Argyro","family":"Syngelaki","sequence":"additional","affiliation":[{"name":"Harris Birthright Research Centre for Fetal Medicine King\u2019s College Hospital  London UK"},{"name":"Department of Women &amp; Children\u2019s Health, School of Life Course &amp; Population Health Sciences King\u2019s College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1266-0711","authenticated-orcid":false,"given":"Kypros H.","family":"Nicolaides","sequence":"additional","affiliation":[{"name":"Harris Birthright Research Centre for Fetal Medicine King\u2019s College Hospital  London UK"},{"name":"Department of Women &amp; Children\u2019s Health, School of Life Course &amp; Population Health Sciences King\u2019s College London  London 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