{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T00:23:56Z","timestamp":1791591836376,"version":"4.3.4"},"reference-count":33,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T00:00:00Z","timestamp":1780531200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T00:00:00Z","timestamp":1780531200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100006306","name":"Sigrid Jus\u00e9liuksen S\u00e4\u00e4ti\u00f6","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006306","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010711","name":"Sy\u00f6p\u00e4s\u00e4\u00e4ti\u00f6","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010711","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100016545","name":"Roche Diagnostics","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100016545","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>HPV primary testing is the preferred method for cervical cancer screening worldwide and enables vaginal self\u2010sampling at home. Self\u2010sampling performs comparably to clinician\u2010collected samples and can improve participation, especially among non\u2010attenders. In Finland, self\u2010sampling has so far been piloted in the Helsinki region. This study evaluated the feasibility and acceptability of self\u2010sampling in Pirkanmaa, providing a representative model of implementation outside the capital region.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and Methods<\/jats:title>\n                    <jats:p>The self\u2010sampling in cervical cancer routine screening (FALCON) study (NCT06931184) targeted women living in Pirkanmaa who did not respond to the initial cervical cancer screening invitation. In a reminder letter, they were offered an opt\u2010in model self\u2010sampling option. Participants ordered a self\u2010sampling kit containing a FLOQSwab (Copan), instructions, and a prepaid return envelope. Samples were analyzed with the Roche Cobas 4800 HPV assay at Fimlab Laboratories. HPV\u2010positive women were referred for cytology testing and managed according to national guidelines. Participants completed two online questionnaires: one at kit order and another 60\u2009days later.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of 16\u2009289 reminder letters, 329 kits were ordered, and 304 (1.9%) samples were returned. Participants (mean age 48 [range 29.9\u201365.8]) were mostly well\u2010educated with previous screening history. Time\u2010saving, reduced discomfort, and lower embarrassment were the main reasons for choosing home\u2010sampling. HPV was detected in 6.9% of the samples, with one case of histological HSIL identified. Most participants found self\u2010sampling easy and comfortable, and nearly all would recommend it to others.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Despite the small number of participants in this first year, the study offers early evidence of the strong acceptability and practicality of self\u2010sampling among women in Pirkanmaa, warranting further evaluation at a larger scale.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/aogs.70273","type":"journal-article","created":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T04:55:42Z","timestamp":1780635342000},"page":"1879-1888","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Introducing self\u2010sampling for cervical cancer screening: A regional implementation study in Pirkanmaa, Finland"],"prefix":"10.1111","volume":"105","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-6643-3916","authenticated-orcid":false,"given":"Saara","family":"Kyll\u00f6nen","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Faculty of Medicine and Health Technology Tampere University  Tampere Finland"},{"name":"Department of Obstetrics and Gynecology Tampere University Hospital  Tampere Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satu","family":"Saloranta","sequence":"additional","affiliation":[{"name":"Fimlab Laboratories  Tampere Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saara","family":"Kares","sequence":"additional","affiliation":[{"name":"Fimlab Laboratories  Tampere Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anu","family":"Mustila","sequence":"additional","affiliation":[{"name":"Fimlab Laboratories  Tampere Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1172-363X","authenticated-orcid":false,"given":"Karolina","family":"Louvanto","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Faculty of Medicine and Health Technology Tampere University  Tampere Finland"},{"name":"Department of Obstetrics and Gynecology Tampere University Hospital  Tampere Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,4]]},"reference":[{"key":"e_1_2_14_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMsr2030640"},{"key":"e_1_2_14_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.33189"},{"key":"e_1_2_14_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ypmed.2021.106900"},{"key":"e_1_2_14_5_1","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-18-1338"},{"key":"e_1_2_14_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2024.02.032"},{"key":"e_1_2_14_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(13)70570-9"},{"key":"e_1_2_14_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.33967"},{"key":"e_1_2_14_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.k4823"},{"key":"e_1_2_14_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2015.07.006"},{"key":"e_1_2_14_11_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2025.2971"},{"key":"e_1_2_14_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ypmed.2022.107096"},{"key":"e_1_2_14_13_1","unstructured":"WHO guideline on self\u2010care interventions for health and well\u2010being 2022 revision. Accessed May 21 2025.https:\/\/www.who.int\/publications\/i\/item\/9789240052192"},{"key":"e_1_2_14_14_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2022.948471"},{"key":"e_1_2_14_15_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2025.1540609"},{"key":"e_1_2_14_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40271-021-00550-y"},{"key":"e_1_2_14_17_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0151978"},{"key":"e_1_2_14_18_1","doi-asserted-by":"publisher","DOI":"10.1080\/14796694.2024.2409625"},{"key":"e_1_2_14_19_1","unstructured":"McE.Monitor Dutch cervical cancer screening programme 2023.2023."},{"key":"e_1_2_14_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.29176"},{"key":"e_1_2_14_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41416-022-02094-w"},{"key":"e_1_2_14_22_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41416-022-01954-9"},{"key":"e_1_2_14_23_1","doi-asserted-by":"publisher","DOI":"10.1097\/LGT.0000000000000476"},{"key":"e_1_2_14_24_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjgh-2020-003743"},{"key":"e_1_2_14_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2014.09.019"},{"key":"e_1_2_14_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0215(19990924)83:1<59::AID-IJC12>3.0.CO;2-N"},{"key":"e_1_2_14_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.34170"},{"key":"e_1_2_14_28_1","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-11-0307"},{"key":"e_1_2_14_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/cyt.12652"},{"key":"e_1_2_14_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.35263"},{"key":"e_1_2_14_31_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1004253"},{"key":"e_1_2_14_32_1","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-18-0480"},{"key":"e_1_2_14_33_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2407-13-353"},{"key":"e_1_2_14_34_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-018-3254-y"}],"container-title":["Acta Obstetricia et Gynecologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aogs.70273","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/aogs.70273","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aogs.70273","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,8]],"date-time":"2026-08-08T06:05:26Z","timestamp":1786169126000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/aogs.70273"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,4]]},"references-count":33,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["10.1111\/aogs.70273"],"URL":"https:\/\/doi.org\/10.1111\/aogs.70273","archive":["Portico"],"relation":{},"ISSN":["0001-6349","1600-0412"],"issn-type":[{"value":"0001-6349","type":"print"},{"value":"1600-0412","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,4]]},"assertion":[{"value":"2025-11-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-18","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-04","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}