{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T15:51:06Z","timestamp":1789487466197,"version":"build-2803163510"},"reference-count":31,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T00:00:00Z","timestamp":1784592000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T00:00:00Z","timestamp":1784592000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Cervical carcinoma can be prevented by treating precancerous lesions, which are classified as low\u2010grade (LSIL) and high\u2010grade (HSIL) squamous intraepithelial lesions. Follow\u2010up of patients diagnosed with LSIL or treated HSIL is typically conducted in secondary care by a gynecologist. However, this may also be conducted in a primary care setting at the general practitioner. This latter approach offers potential benefits such as lower healthcare costs and care closer to home. However, the effectiveness of follow\u2010up by general practitioners is unknown.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and Methods<\/jats:title>\n                    <jats:p>This retrospective cohort study included patients diagnosed with LSIL or treated HSIL by the gynecologist, with no prior history of SIL or cervical cancer, who either underwent cytological follow\u2010up at the gynecologist or the general practitioner. The primary outcome was loss to follow\u2010up at 12\u2009months for LSIL and 24\u2009months for treated HSIL.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 691 patients were followed up by the gynecologist, and 1172 by the general practitioner. In the LSIL group, 38.1% (333\/874) of patients followed up by a general practitioner were lost to follow\u2010up at 12\u2009months, compared with 16.6% (92\/554) of those followed up by a gynecologist (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). For treated HSIL, 44.3% (132\/298) were lost to follow\u2010up at 24\u2009months in the general practitioner group, versus 24.1% (33\/137) in the gynecologist group (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Follow\u2010up by a general practitioner after a diagnosis of LSIL or treated HSIL is associated with nearly twice the rate of loss to follow\u2010up compared to follow\u2010up by a gynecologist.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/aogs.70301","type":"journal-article","created":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T23:26:28Z","timestamp":1784676388000},"page":"2081-2088","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Loss to follow\u2010up in patients diagnosed with or treated for low\u2010 and high\u2010grade squamous intraepithelial lesions: A comparison of general practitioner\u2010 and gynecologist\u2010led surveillance"],"prefix":"10.1111","volume":"105","author":[{"given":"Lieke","family":"van de Kam","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Amphia  Breda the Netherlands"},{"name":"Grow Research Institute for Oncology and Reproduction Maastricht University  Maastricht the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert","family":"Siebers","sequence":"additional","affiliation":[{"name":"Palga Dutch Pathology Registry  Houten The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruud","family":"Bekkers","sequence":"additional","affiliation":[{"name":"Grow Research Institute for Oncology and Reproduction Maastricht University  Maastricht the Netherlands"},{"name":"Department of Obstetrics and Gynecology and Catharina Cancer Institute Catharina Hospital  Eindhoven The Netherlands"},{"name":"Department of Obstetrics and Gynecology Radboud University Medical Centre  Nijmegen the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dennis","family":"van Hamont","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Amphia  Breda the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0487-0631","authenticated-orcid":false,"given":"Jurgen","family":"Piek","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology and Catharina Cancer Institute Catharina Hospital  Eindhoven The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,21]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2214-109X(19)30482-6"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2214-109X(22)00241-8"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2018.10897"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2018.10400"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/PGP.0b013e31826916c7"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000004384"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1003665"},{"key":"e_1_2_13_9_1","unstructured":"Federatie Medisch Specialisten.CIN AIS en VAIN \u2010 Follow\u2010up \u2010 Richtlijn \u2010 Richtlijnendatabase [CIN AIS and VAIN \u2010 Follow\u2010up \u2010 guideline \u2010 guideline database].2015https:\/\/richtlijnendatabase.nl\/richtlijn\/cin_ais_en_vain\/follow_up.html[cited 2025 may 14]"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/CJI.0000000000000414"},{"key":"e_1_2_13_11_1","unstructured":"Castor EDC.Castor Electronic Data Capture.2019https:\/\/castoredc.com"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1155\/2007\/971816"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.22114"},{"key":"e_1_2_13_14_1","unstructured":"Integraal Kankercentrum Nederland (IKNL).Monitor bevolkingsonderzoek baarmoederhalskanker. 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