{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T09:44:02Z","timestamp":1785836642131,"version":"3.56.0"},"reference-count":40,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T00:00:00Z","timestamp":1785801600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T00:00:00Z","timestamp":1785801600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100009708","name":"Novo Nordisk Fonden","doi-asserted-by":"publisher","award":["NNF21OC0071037"],"award-info":[{"award-number":["NNF21OC0071037"]}],"id":[{"id":"10.13039\/501100009708","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"abstract":"Abstract<\/jats:title>\n \n Introduction<\/jats:title>\n A transabdominal cerclage is inserted to prevent recurrent midtrimester loss and spontaneous preterm birth. The transabdominal cerclage often remains as a permanent foreign body for years. Synthetic materials within the abdomen, cesarean birth, and prior adverse pregnancy outcomes have each been associated with long\u2010term complications or poorer health\u2010related quality\u2010of\u2010life. However, the long\u2010term effects of a permanent transabdominal cerclage have not been investigated. We aimed to evaluate patient\u2010reported late effects and health\u2010related quality\u2010of\u2010life in Danish women who underwent transabdominal cerclage between 2004 and 2025.<\/jats:p>\n <\/jats:sec>\n \n Material and Methods<\/jats:title>\n \n In this nationwide cohort study, women with a transabdominal cerclage were matched in a 1:1:1 ratio to two comparison groups: (1)women without transabdominal cerclage who had a cesarean birth, and (2)women without transabdominal cerclage who had a non\u2010instrumental vaginal birth and no prior cesarean birth. Participants completed validated questionnaires assessing quality\u2010of\u2010life, anxiety and depression, bladder discomfort, pelvic pain and sexual health. The primary outcome was the General Health scale in SF\u201036. Domain\u2010 and total scale scores were compared between the groups using multiple linear regression. The study was pre\u2010registered on\n clinicaltrials.gov<\/jats:ext-link>\n (NCT06875401).\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n Two hundred three women with a transabdominal cerclage, 90 with a cesarean section, and 98 with a vaginal birth participated. The mean General Health score did not differ between groups by a predefined minimally important difference of 10 points. Adjusted mean differences were\u2009\u2212\u20094.0 points (95% CI \u20109.5\u20131.4) for women with cesarean birth and \u22120.6 (95% \u2010CI\u20106.2\u20134.9) for women with vaginal birth in comparison to the transabdominal cerclage group. Mental health, bladder discomfort, pelvic pain, and sexual health symptom burdens were similar between groups. Response rates were higher in the transabdominal cerclage group, which may have introduced selection bias. Cerclage\u2010related complications leading to suture removal after completed pregnancies were rare (3\/203 women, 1.5%). Quality\u2010of\u2010life scores tended to be higher with longer time since cerclage procedure.<\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n Permanent transabominal cerclage was not associated with poorer self\u2010reported general health compared with women without transabominal cerclage, regardless of mode of birth. These findings support that a permanent transabominal cerclage does not appear to have long\u2010term negative health effects.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/aogs.70324","type":"journal-article","created":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T08:47:36Z","timestamp":1785833256000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Quality\u2010of\u2010life and late effects after transabdominal cerclage: A nationwide matched cohort study"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1702-3933","authenticated-orcid":false,"given":"Lea Kirstine","family":"Hansen","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Aarhus University Hospital Aarhus Denmark"},{"name":"Department of Surgery G\u00f8dstrup Regional Hospital Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9856-6621","authenticated-orcid":false,"given":"Julie","family":"Glavind","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Aarhus University Hospital Aarhus Denmark"},{"name":"Department of Clinical Medicine Aarhus University Hospital Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5273-3132","authenticated-orcid":false,"given":"Andrew H.","family":"Shennan","sequence":"additional","affiliation":[{"name":"Department of Women and Children's Health St Thomas' Hospital, King's College London London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6449-6426","authenticated-orcid":false,"given":"Niels","family":"Uldbjerg","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Aarhus University Hospital Aarhus Denmark"},{"name":"Department of Clinical Medicine Aarhus University Hospital Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6177-5780","authenticated-orcid":false,"given":"Stina","family":"Lou","sequence":"additional","affiliation":[{"name":"Center for Fetal Diagnostics, Department of Clinical Medicine Aarhus University Aarhus N Denmark"},{"name":"DEFACTUM \u2013 Public Health Research, Central Denmark Region Aarhus N Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3868-106X","authenticated-orcid":false,"given":"Ulrik Schi\u00f8ler","family":"Kesmodel","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology Aalborg University Hospital Aalborg Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1637-6040","authenticated-orcid":false,"given":"Pernille Tine","family":"Jensen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Aarhus University Hospital Aarhus Denmark"},{"name":"Department of Clinical Medicine Aarhus University Hospital Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,4]]},"reference":[{"issue":"1","key":"e_1_2_14_2_1","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1097\/AOG.0b013e31821fd5b0","article-title":"Cervical length screening with ultrasound\u2010indicated cerclage compared with history\u2010indicated cerclage for prevention of preterm birth: a meta\u2010analysis","volume":"118","author":"Berghella V","year":"2011","journal-title":"Obstet Gynecol"},{"key":"e_1_2_14_3_1","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.ejogrb.2022.01.002","article-title":"Efficacy of laparoscopic and trans\u2010abdominal cerclage (TAC) in patients with cervical insufficiency: a systematic review and meta\u2010analysis","volume":"270","author":"Marchand G","year":"2022","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"issue":"3","key":"e_1_2_14_4_1","doi-asserted-by":"crossref","first-page":"261.e1","DOI":"10.1016\/j.ajog.2019.09.040","article-title":"MAVRIC: a multicenter randomized controlled trial of transabdominal vs transvaginal cervical cerclage","volume":"222","author":"Shennan A","year":"2020","journal-title":"Am J Obstet Gynecol"},{"issue":"1","key":"e_1_2_14_5_1","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajogmf.2023.101227","article-title":"Favorable surgical and obstetrical outcomes in pre\u2010 and postconceptional laparoscopic abdominal cerclage: a large multicenter cohort study","volume":"6","author":"Abdulrahman N","year":"2024","journal-title":"American Journal of Obstetrics andAmp; 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