{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T06:05:24Z","timestamp":1777356324374,"version":"3.51.4"},"reference-count":28,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2013,1,11]],"date-time":"2013-01-11T00:00:00Z","timestamp":1357862400000},"content-version":"vor","delay-in-days":10,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Artificial Organs"],"published-print":{"date-parts":[[2013,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\u2002 Single\u2010lumen cannula venovenous (VV) extracorporeal membrane oxygenation (<jats:styled-content style=\"fixed-case\">ECMO<\/jats:styled-content>) is a special extracorporeal life support (<jats:styled-content style=\"fixed-case\">ECLS<\/jats:styled-content>) technique used for neonatal and pediatric refractory hypoxemia. This is an alternative flow rate <jats:styled-content style=\"fixed-case\">ECLS<\/jats:styled-content> that consists of successive clamping on the drainage and the injection lines. Currently, the <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>rmand\u2010<jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>rousseau's pediatric intensive care unit remains the only pediatric <jats:styled-content style=\"fixed-case\">ECMO<\/jats:styled-content> center proposing this partial assistance. This article details a technical note and a retrospective analysis of our experience in refractory hypoxemia. The retrospective study, from 2007 to 2011, included all pediatric and neonatal patients treated by single\u2010lumen cannula <jats:styled-content style=\"fixed-case\">VV ECMO<\/jats:styled-content>. The study was focused on pre\u2010<jats:styled-content style=\"fixed-case\">ECMO<\/jats:styled-content> patient characteristics and complications during <jats:styled-content style=\"fixed-case\">ECMO<\/jats:styled-content> course. During the last 5 years, 67 pediatric patients were assisted by this single\u2010lumen cannula <jats:styled-content style=\"fixed-case\">VV ECMO<\/jats:styled-content>. Sixty\u2010one patients (91%) were newborns. Thirty\u2010nine patients presented with meconium aspiration syndrome (58%), which was the most frequent etiology. Before cannulation, mean oxygenation index (<jats:styled-content style=\"fixed-case\">OI<\/jats:styled-content>) was 32\u2009\u00b1\u200911, alveolar\u2010arterial oxygen difference was 604\u2009\u00b1\u200947\u2009mm\u2009<jats:styled-content style=\"fixed-case\">Hg<\/jats:styled-content>, and partial pressure arterial oxygen\/fraction inspired oxygen ratio was 59.2\u2009\u00b1\u200935.8. Forty\u2010eight patients (72%) presented pulmonary hypertension, and 66 patients were treated by nitric oxide (98%). Fifty patients (75%) were treated by vasopressors or inotropic drugs. Average duration of <jats:styled-content style=\"fixed-case\">ECMO<\/jats:styled-content> was 13.2\u2009\u00b1\u20097.8 days. There were forty\u2010six survivors (69%). The worst prognosis was for respiratory syncytial virus pneumonia. Complications like acute renal injury and hematologic and transfusion acts were not so different than those observed in classical <jats:styled-content style=\"fixed-case\">ECMO<\/jats:styled-content> techniques. Nevertheless, 19 patients presented a stroke (28% of the overall population), but this high rate did not seem to be due to the <jats:styled-content style=\"fixed-case\">ECLS<\/jats:styled-content> technique used. Single\u2010lumen cannula <jats:styled-content style=\"fixed-case\">VV ECMO<\/jats:styled-content> is a partial and efficient <jats:styled-content style=\"fixed-case\">ECMO<\/jats:styled-content> support. Our experience shows that this technique is as efficient and less invasive than two cannulas <jats:styled-content style=\"fixed-case\">ECMO<\/jats:styled-content>. The single\u2010lumen cannula <jats:styled-content style=\"fixed-case\">VV ECMO<\/jats:styled-content> is a simple and safe <jats:styled-content style=\"fixed-case\">ECLS<\/jats:styled-content> support used for neonatal or pediatric refractory hypoxemia. Because this is a partial assistance, it is a promising <jats:styled-content style=\"fixed-case\">ECLS<\/jats:styled-content> support.<\/jats:p>","DOI":"10.1111\/aor.12024","type":"journal-article","created":{"date-parts":[[2013,1,11]],"date-time":"2013-01-11T11:45:57Z","timestamp":1357904757000},"page":"57-65","source":"Crossref","is-referenced-by-count":11,"title":["Pediatric Single\u2010Lumen Cannula Venovenous Extracorporeal Membrane Oxygenation: A <scp>F<\/scp>rench Center Experience"],"prefix":"10.1111","volume":"37","author":[{"given":"Pierre\u2010Louis","family":"L\u00e9ger","sequence":"first","affiliation":[{"name":"Service de R\u00e9animation N\u00e9onatale et P\u00e9diatrique H\u00f4pital Armand\u2010Trousseau  Paris France"},{"name":"Universit\u00e9 Pierre et Marie Curie\u2010UPMC  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julia","family":"Guilbert","sequence":"additional","affiliation":[{"name":"Service de R\u00e9animation N\u00e9onatale et P\u00e9diatrique H\u00f4pital Armand\u2010Trousseau  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S\u00e9gol\u00e8ne","family":"Isambert","sequence":"additional","affiliation":[{"name":"Service de R\u00e9animation N\u00e9onatale et P\u00e9diatrique H\u00f4pital Armand\u2010Trousseau  Paris France"},{"name":"Universit\u00e9 Pierre et Marie Curie\u2010UPMC  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nolwenn","family":"Le Sach\u00e9","sequence":"additional","affiliation":[{"name":"Service de R\u00e9animation N\u00e9onatale et P\u00e9diatrique H\u00f4pital Armand\u2010Trousseau  Paris France"},{"name":"Universit\u00e9 Pierre et Marie Curie\u2010UPMC  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fazia","family":"Hallalel","sequence":"additional","affiliation":[{"name":"Service de R\u00e9animation N\u00e9onatale et P\u00e9diatrique H\u00f4pital Armand\u2010Trousseau  Paris 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