{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T11:59:30Z","timestamp":1791979170064,"version":"4.4.0"},"reference-count":14,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2013,7,19]],"date-time":"2013-07-19T00:00:00Z","timestamp":1374192000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Artificial Organs"],"published-print":{"date-parts":[[2013,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Assessment of respiratory function using combined oximetry\u2010cutaneous capnography has never been evaluated in patients with myasthenia gravis (<jats:styled-content style=\"fixed-case\">MG<\/jats:styled-content>). We investigated the effects of double filtration plasmapheresis (<jats:styled-content style=\"fixed-case\">DFPP<\/jats:styled-content>) on respiratory status in 18 <jats:styled-content style=\"fixed-case\">MG<\/jats:styled-content> patients. Results of combined oximetry and transcutaneous capnography, <jats:styled-content style=\"fixed-case\">MG<\/jats:styled-content> scores, and acetylcholine receptor antibody titers before and after <jats:styled-content style=\"fixed-case\">DFPP<\/jats:styled-content> treatment were compared. The respiratory monitoring was performed at three time periods (morning, afternoon, and sleep). Mean <jats:styled-content style=\"fixed-case\">MG<\/jats:styled-content> score was markedly lower after <jats:styled-content style=\"fixed-case\">DFPP<\/jats:styled-content> treatment (5.7) than before treatment (7.9). Before <jats:styled-content style=\"fixed-case\">DFPP<\/jats:styled-content>, the minimum pulse oximetric saturation (<jats:styled-content style=\"fixed-case\"><jats:roman>SpO<\/jats:roman><jats:sub>2<\/jats:sub><\/jats:styled-content>) level obtained during the night session was significantly lower (<jats:italic>P<\/jats:italic>\u2009=\u20090.0513 and <jats:italic>P<\/jats:italic>\u2009=\u20090.0199) than the levels obtained during the two daytime sessions. A similar phenomenon was noted for maximum transcutaneous carbon dioxide tension (<jats:styled-content style=\"fixed-case\"><jats:roman>PtcCO<\/jats:roman><jats:sub>2<\/jats:sub><\/jats:styled-content>). After <jats:styled-content style=\"fixed-case\">DFPP<\/jats:styled-content> treatment, the maximum and mean <jats:styled-content style=\"fixed-case\"><jats:roman>PtcCO<\/jats:roman><jats:sub>2<\/jats:sub><\/jats:styled-content> levels were significantly higher (<jats:italic>P<\/jats:italic>\u2009=\u20090.0056) in the morning than in the afternoon. Of all the respiratory function parameters measured, only minimum <jats:styled-content style=\"fixed-case\"><jats:roman>SpO<\/jats:roman><jats:sub>2<\/jats:sub><\/jats:styled-content> levels obtained during morning sessions before <jats:styled-content style=\"fixed-case\">DFP<\/jats:styled-content> treatment differed significantly from those obtained after <jats:styled-content style=\"fixed-case\">DFPP<\/jats:styled-content> treatment (<jats:italic>P<\/jats:italic>\u2009=\u20090.0322). Overall, however, minimum <jats:styled-content style=\"fixed-case\"><jats:roman>SpO<\/jats:roman><jats:sub>2<\/jats:sub><\/jats:styled-content> levels as well as mean and maximum <jats:styled-content style=\"fixed-case\"><jats:roman>PtcCO<\/jats:roman><jats:sub>2<\/jats:sub><\/jats:styled-content> levels improved significantly during sleep after <jats:styled-content style=\"fixed-case\">DFPP<\/jats:styled-content>. In conclusion, we found that respiratory function abnormalities were common in myasthenic patients without clinical respiratory symptoms. <jats:styled-content style=\"fixed-case\">DFPP<\/jats:styled-content> treatment resulted in minimal improvement of respiratory parameters.<\/jats:p>","DOI":"10.1111\/aor.12128","type":"journal-article","created":{"date-parts":[[2013,7,19]],"date-time":"2013-07-19T09:27:28Z","timestamp":1374226048000},"page":"1076-1079","source":"Crossref","is-referenced-by-count":8,"title":["Effects of Double Filtration Plasmapheresis on Nocturnal Respiratory Function in Myasthenic Patients"],"prefix":"10.1111","volume":"37","author":[{"given":"Jiann\u2010Horng","family":"Yeh","sequence":"first","affiliation":[{"name":"Department of Neurology Shin Kong Wu Ho\u2010Su Memorial Hospital  Taipei Taiwan"},{"name":"College of Medicine Fu\u2010Jen Catholic University  Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chia\u2010Mo","family":"Lin","sequence":"additional","affiliation":[{"name":"College of Medicine Fu\u2010Jen Catholic University  Taipei Taiwan"},{"name":"Sleep Center Shin Kong Wu Ho\u2010Su Memorial Hospital  Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei\u2010Hung","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Neurology Shin Kong Wu Ho\u2010Su Memorial Hospital  Taipei Taiwan"},{"name":"College of Medicine Taipei Medical University  Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hou\u2010Chang","family":"Chiu","sequence":"additional","affiliation":[{"name":"Department of Neurology Shin Kong Wu Ho\u2010Su Memorial Hospital  Taipei Taiwan"},{"name":"College of Medicine Fu\u2010Jen Catholic University  Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,7,19]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(09)70063-8"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1159\/000196734"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1594.2009.00975.x"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0025-6196(11)63619-7"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-199707000-00029"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1159\/000081515"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.128.3.1291"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/00001503-200412000-00014"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(77)92639-3"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0404.2001.104002078.x"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0404.1999.tb07336.x"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02230908"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2006.01666.x"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ncl.2005.08.004"}],"container-title":["Artificial Organs"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Faor.12128","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aor.12128","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,5]],"date-time":"2023-10-05T00:13:23Z","timestamp":1696464803000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/aor.12128"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,7,19]]},"references-count":14,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2013,12]]}},"alternative-id":["10.1111\/aor.12128"],"URL":"https:\/\/doi.org\/10.1111\/aor.12128","archive":["Portico"],"relation":{},"ISSN":["0160-564X","1525-1594"],"issn-type":[{"value":"0160-564X","type":"print"},{"value":"1525-1594","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,7,19]]}}}