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In order to estimate red blood cell (RBC) damage in blood flows, many models have been proposed in the past. Most models have been validated by their respective authors. However, the accuracy and the validity range of these models remains unclear. In this work, the most established hemolysis models compatible with computational fluid dynamics of full\u2010scale devices are described and assessed by comparing two selected reference experiments: a simple rheometric flow and a more complex hemodialytic flow through a needle. The quantitative comparisons show very large deviations concerning hemolysis predictions, depending on the model and model parameter. In light of the current results, two simple power\u2010law models deliver the best compromise between computational efficiency and obtained accuracy. Finally, hemolysis has been computed in an axial blood pump. The reconstructed geometry of a HeartMate II shows that hemolysis occurs mainly at the tip and leading edge of the rotor blades, as\u00a0well as at the\u00a0leading edge of the diffusor vanes.<\/jats:p>","DOI":"10.1111\/aor.12871","type":"journal-article","created":{"date-parts":[[2017,6,23]],"date-time":"2017-06-23T05:56:41Z","timestamp":1498197401000},"page":"603-621","source":"Crossref","is-referenced-by-count":121,"title":["A Review of Hemolysis Prediction Models for Computational Fluid Dynamics"],"prefix":"10.1111","volume":"41","author":[{"given":"Hai","family":"Yu","sequence":"first","affiliation":[{"name":"Laboratory of Fluid Dynamics &amp; Technical Flows Institute of Fluid Dynamics and Thermodynamics, Otto\u2010von\u2010Guericke University Magdeburg Magdeburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastian","family":"Engel","sequence":"additional","affiliation":[{"name":"Laboratory of Fluid Dynamics &amp; Technical Flows Institute of Fluid Dynamics and Thermodynamics, Otto\u2010von\u2010Guericke University Magdeburg Magdeburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G\u00e1bor","family":"Janiga","sequence":"additional","affiliation":[{"name":"Laboratory of Fluid Dynamics &amp; Technical Flows Institute of Fluid Dynamics and Thermodynamics, Otto\u2010von\u2010Guericke University Magdeburg Magdeburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominique","family":"Th\u00e9venin","sequence":"additional","affiliation":[{"name":"Laboratory of Fluid Dynamics &amp; Technical Flows Institute of Fluid Dynamics and Thermodynamics, Otto\u2010von\u2010Guericke University Magdeburg Magdeburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,6,23]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/aor.12542"},{"key":"e_1_2_10_3_1","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1111\/aor.12567","article-title":"CFD\u2010based design optimization method for Archimedes screw blood pumps","volume":"40","author":"H Yu","year":"2015","journal-title":"Artif Organs"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAT.0000000000000261"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.apm.2012.09.020"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1053-0770(96)80050-4"},{"key":"e_1_2_10_7_1","first-page":"121","article-title":"Role of hydrodynamic shear in the cultivation of animal, plant and microbial cells","volume":"62","author":"Joshi J","year":"1996","journal-title":"Chem Eng J"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1080\/20013891081692"},{"key":"e_1_2_10_9_1","volume-title":"Hemodynamical Flows: Modeling, Analysis and Simulation","author":"Galdi GP","year":"2008"},{"key":"e_1_2_10_10_1","unstructured":"US Food and Drug Administration. 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