{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T03:02:05Z","timestamp":1769569325974,"version":"3.49.0"},"reference-count":19,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2018,9,11]],"date-time":"2018-09-11T00:00:00Z","timestamp":1536624000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Artificial Organs"],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We aim to evaluate clinical outcomes of emergent extracorporeal membrane oxygenation (ECMO) implantation in newborns with life\u2010threatening meconium aspiration syndrome (MAS) in peripheral hospitals with Hub and Spoke (HandS) setting. We retrospectively reviewed all neonates presenting with MAS, with no other comorbidities, treated with HandS ECMO, in peripheral hospitals. Team activation time (TAT) was described as the time from first alerting call to ECMO support initiation. From May 2014 to December 2016, 4 patients met our inclusion criteria. In addition, 2 cases occurred on the same day, requiring a second simultaneous HandS ECMO team activation. All patients were younger than 8 days of life (1, 1, 4, and 7), with a mean BSA 0.21\u2009\u00b1\u20090.03m<jats:sup>2<\/jats:sup>, and TAT of 203, 265, 320, and 340 min. One patient presented ventricular fibrillation after priming administration. Veno\u2010arterial ECMO was established in all patients after uneventful surgical neck vessels cannulation (right carotid artery and jugular vein). Mean time from skin incision to ECMO initiation was 19\u2009\u00b1\u20091.4 min. Mean length of ECMO support was 2.75\u2009\u00b1\u20091.3 days. All patients were weaned off support without complications. At a mean follow up of 20.5\u2009\u00b1\u20097.8 months, all patients are alive, with no medications, normal somatic growth, and neuropsychological development. MAS is a life\u2010threatening condition that can be successfully managed with ECMO support. A highly trained multidisciplinary HandS ECMO team is crucial for the successful management of these severely ill newborns in peripheral hospitals.<\/jats:p>","DOI":"10.1111\/aor.13270","type":"journal-article","created":{"date-parts":[[2018,9,11]],"date-time":"2018-09-11T13:32:50Z","timestamp":1536672770000},"page":"76-80","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["<scp>H<\/scp>and<scp>S<\/scp><scp>ECMO<\/scp>: Preliminary Experience With \u201cHub and Spoke\u201d Model in Neonates With Meconium Aspiration Syndrome"],"prefix":"10.1111","volume":"43","author":[{"given":"Dario","family":"Fichera","sequence":"first","affiliation":[{"name":"Cardiovascular Perfusion Unit, Department of Cardiac, Thoracic and Vascular Sciences, University of Padua  Padua Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabio","family":"Zanella","sequence":"additional","affiliation":[{"name":"Cardiovascular Perfusion Unit, Department of Cardiac, Thoracic and Vascular Sciences, University of Padua  Padua Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Assunta","family":"Fabozzo","sequence":"additional","affiliation":[{"name":"Cardiac Surgery Unit, Department of Cardiac, Thoracic and Vascular Sciences, University of Padua  Padua Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicoletta","family":"Doglioni","sequence":"additional","affiliation":[{"name":"Department of Women and Children Health, University of Padua  Padua Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniele","family":"Trevisanuto","sequence":"additional","affiliation":[{"name":"Department of Women and Children Health, University of Padua  Padua Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisabetta","family":"Lolli","sequence":"additional","affiliation":[{"name":"Department of Women and Children Health, University of Padua  Padua Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vladimiro","family":"Vida","sequence":"additional","affiliation":[{"name":"Pediatric and Congenital Cardiac Surgery Unit, Department of Cardiac, Thoracic and Vascular Sciences University of Padua  Padua Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enrico","family":"Ceccherini","sequence":"additional","affiliation":[{"name":"Cardiovascular Perfusion Unit, Department of Cardiac, Thoracic and Vascular Sciences, University of Padua  Padua Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Agostino","family":"Ebraico","sequence":"additional","affiliation":[{"name":"Cardiovascular Perfusion Unit, Department of Cardiac, Thoracic and Vascular Sciences, University of Padua  Padua Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanni","family":"Stellin","sequence":"additional","affiliation":[{"name":"Pediatric and Congenital Cardiac Surgery Unit, Department of Cardiac, Thoracic and Vascular Sciences University of Padua  Padua Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0343-8118","authenticated-orcid":false,"given":"Massimo","family":"Padalino","sequence":"additional","affiliation":[{"name":"Pediatric and Congenital Cardiac Surgery Unit, Department of Cardiac, Thoracic and Vascular Sciences University of Padua  Padua Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,9,11]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/965159"},{"key":"e_1_2_7_3_1","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1542\/peds.95.3.400","article-title":"Predictors of failure of high\u2010frequency oscillatory ventilation in term infants with severe respiratory failure","volume":"95","author":"Paranka MS","year":"1995","journal-title":"Pediatrics"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2016.00063"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/jp.2008.152"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/jp.2008.241"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)61069-2"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(05)81098-4"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/ped.13178"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201404-0630CP"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2014.06.025"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2010.11.018"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2007.09.021"},{"key":"e_1_2_7_14_1","unstructured":"Extracorporeal Life Support Organization. ELSO Neonatal Respiratory Failure Supplement to the ELSO General Guidelines. Available at:http:\/\/www.elso.org. Accessed September 5 2017."},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/cc12512"},{"key":"e_1_2_7_16_1","unstructured":"ECMOnet Censimento delle Terapie Intensive Italiane. Available at:http:\/\/www.ecmonet.org\/index.php?pag=cartina&id_sezione=68&id_supersezione=65. Accessed September 4 2017."},{"key":"e_1_2_7_17_1","first-page":"262","article-title":"Mobile ECMO team for inter\u2010hospital transportation of patients with ARDS: a retrospective case series","volume":"6","author":"Lucchini A","year":"2014","journal-title":"Heart Lung Vessel"},{"key":"e_1_2_7_18_1","unstructured":"Extracorporeal Life Support Organization. ELSO Guidelines. Available at:http:\/\/www.elso.org. Accessed September 5 2017."},{"key":"e_1_2_7_19_1","unstructured":"Extracorporeal Life Support Organization. ELSO Guidelines for ECMO transport 2015\u20132018. 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