{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T11:29:42Z","timestamp":1790508582714,"version":"4.1.0"},"reference-count":28,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2019,10,20]],"date-time":"2019-10-20T00:00:00Z","timestamp":1571529600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2019,10,20]],"date-time":"2019-10-20T00:00:00Z","timestamp":1571529600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Artificial Organs"],"published-print":{"date-parts":[[2020,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Acute kidney injury (AKI) is frequent in patients scheduled for implantation of a left ventricular assist device (LVAD) and associated with increased mortality. Although several risk models for the prediction of postoperative renal replacement therapy (RRT) have been developed for cardiothoracic patients, none of these scoring systems have been validated in LVAD\u00a0patients. A retrospective, single center analysis of all patients undergoing LVAD implantation between September 2013 and July 2016 was performed. Primary outcome was AKI requiring RRT within 14 days after surgery. The predictive capacity of the Cleveland\u00a0Clinic\u00a0Score (CCS), the Society\u00a0of\u00a0Thoracic\u00a0Surgeons\u00a0Score (STS), and the Simplified Renal Index Score\u00a0(SRI) were evaluated. 76 patients underwent LVAD\u00a0implantation, 19 patients were excluded due to preoperative RRT. RRT was associated with a prolonged ventilation time, length of stay\u00a0on the ICU and 180 day mortality (14(60.9%) vs 6(17.6%),\n                    <jats:italic>P<\/jats:italic>\n                    \u00a0&lt;\u00a0.01). Whereas the Thakar Score (7.43\u00a0\u00b1\u00a01.75 vs 6.44\u00a0\u00b1\u00a01.44,\n                    <jats:italic>P<\/jats:italic>\n                    \u00a0=\u00a0.02) and the Mehta Score (28.12\u00a0\u00b1\u00a015.08 vs 21.53\u00a0\u00b1\u00a05.43,\n                    <jats:italic>P<\/jats:italic>\n                    \u00a0=\u00a0.02) were significantly higher in patients with RRT than in those without RRT, the SRI did not differ between these groups (3.96\u00a0\u00b1\u00a01.15 vs 3.44\u00a0\u00b1\u00a01.05,\n                    <jats:italic>P\u00a0<\/jats:italic>\n                    =\u00a0.08). Using ROC\u00a0analyses, CCS, STS, and SRI showed moderate predictive capacity for RRT with an AUC of 0.661 \u00b1 0.073 (\n                    <jats:italic>P<\/jats:italic>\n                    \u00a0=\u00a0.040), 0.637\u00a0\u00b1\u00a00.079 (\n                    <jats:italic>P<\/jats:italic>\n                    \u00a0=\u00a0.792), and 0.618\u00a0\u00b1\u00a00.075 (\n                    <jats:italic>P<\/jats:italic>\n                    \u00a0=\u00a0.764), respectively, with comparable accuracy in the Delong test. Using univariate logistic regression analysis, only the De Ritis\u00a0Ratio (OR 2.67,\n                    <jats:italic>P<\/jats:italic>\n                    \u00a0=\u00a0.034) and MELD (OR 1.11,\n                    <jats:italic>P<\/jats:italic>\n                    \u00a0=\u00a0.028) were identified as predictors of postoperative RRT. Risk scores which are\u00a0predictive in general cardiac surgery cannot predict RRT in patients after LVAD implantation. Therefore, it seems to be necessary to develop a specific risk score for this patient population.\n                  <\/jats:p>","DOI":"10.1111\/aor.13548","type":"journal-article","created":{"date-parts":[[2019,7,30]],"date-time":"2019-07-30T10:18:01Z","timestamp":1564481881000},"page":"162-173","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Prediction of acute kidney injury after left ventricular assist device implantation: Evaluation of clinical risk scores"],"prefix":"10.1111","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7788-1174","authenticated-orcid":false,"given":"Kevin","family":"Pilarczyk","sequence":"first","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery, West German Heart and Vascular Center Essen University Hospital Essen Essen Germany"},{"name":"Department of Critical Care Medicine imland Klinik Rendsburg Rendsburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henning","family":"Carstens","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery, West German Heart and Vascular Center Essen University Hospital Essen Essen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2801-7942","authenticated-orcid":false,"given":"Maria","family":"Papathanasiou","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Vascular Medicine, West German Heart and Vascular Center Essen University Hospital Essen Essen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Luedike","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Vascular Medicine, West German Heart and Vascular Center Essen University Hospital Essen Essen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Achim","family":"Koch","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery, West German Heart and Vascular Center Essen University Hospital Essen Essen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heinz","family":"Jakob","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery, West German Heart and Vascular Center Essen University Hospital Essen Essen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Markus","family":"Kamler","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery, West German Heart and Vascular Center Essen University Hospital Essen Essen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikolaus","family":"Pizanis","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery, West German Heart and Vascular Center Essen University Hospital Essen Essen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,10,20]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.00240605"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.06210612"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2016.5828"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2004040331"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.106.635573"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.297.16.1801"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-138-1-200301070-00010"},{"key":"e_1_2_8_9_1","first-page":"472","article-title":"Different surgical strategies for implantation of continuous\u2010flow VADs\u2014experience from Deutsches Herzzentrum Berlin","volume":"3","author":"Krabatsch T","year":"2014","journal-title":"Ann Cardiothorac Surg."},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0036-1592124"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2005.11.457"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2010.04.014"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e3181a00a43"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1603017"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2011.09.010"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10741-015-9481-z"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2010111124"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2015.01.447"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2012.08.076"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2016.12.018"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.814863"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0174262"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1097\/HCO.0000000000000150"},{"key":"e_1_2_8_24_1","article-title":"Gender 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