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Its association with tacrolimus greatly improved kidney transplant (KT) prognosis by significantly reducing the incidence of posttransplant acute rejection. MMF is also reputed to be a safe medication, but the frequency of the gastrointestinal complications associated with it, even minor ones, has induced the marketing of a second molecule called enteric\u2010coated mycophenolate sodium. This late form of mycophenolate was supposed to be better tolerated thanks to its pharmacokinetic properties but the studies did not show significant differences between the two molecules. Otherwise, the combination of MMF with tacrolimus has significantly increased the risk of infections, particularly viral, and of neoplasia. To reduce this risk and avoid any situation of under\u00a0or overexposure while remaining effective, only a strict and long\u2010term monitoring of MMF allows the maintenance of already established therapeutic targets within the predefined ranges. In KT, individualizing the prescription and targets of MMF according to immunologic risk, global immunosuppression, and posttransplant period, as for other immunosuppressants, is open to discussion and may be beneficial.<\/jats:p>","DOI":"10.1111\/aor.13623","type":"journal-article","created":{"date-parts":[[2019,12,27]],"date-time":"2019-12-27T01:31:01Z","timestamp":1577410261000},"page":"561-576","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Mycophenolates: The latest modern and potent immunosuppressive drugs in adult kidney transplantation: What we should know about them?"],"prefix":"10.1111","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9404-6995","authenticated-orcid":false,"given":"Yassamine","family":"Bentata","sequence":"first","affiliation":[{"name":"Nephrology and Kidney Transplantation Unit University Hospital Mohammed VI University Mohammed First Oujda Morocco"},{"name":"Laboratory 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