{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T00:39:28Z","timestamp":1747183168462,"version":"3.40.5"},"reference-count":8,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2020,7,12]],"date-time":"2020-07-12T00:00:00Z","timestamp":1594512000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Artificial Organs"],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Ventricular assist devices (VADs) are considered the standard of care for end\u2010stage heart failure (HF) patients. Despite increasing confidence in the technology, evidence data, endorsement by scientific societies and guidelines, the number of implants reached a steady state and is not increasing at the expected pace. This is most likely related to complications that are still burdening the technology and consequently excluding the most needy, ill, and fragile population. In this manuscript we are reporting a single\u2010center experience in a very fragile, elderly and end\u2010stage HF population, with a superficial, partial support device: the CircuLite Synergy. The patients were included in the pre\u2010CE mark clinical study and consequently the device underwent technical adjustment during the support, based on the complications recorded. At our institution were implanted 6 patients overall: 3 patients survived to discharge and 2 survived up to 5 years. Most of the complications recorded were due to patients\u2019 frailty and overall clinical conditions. The initial experience with the CircuLite Synergy device is proving that a more \u201csuperficial\u201d device might be more tolerable in an elderly, frail population. Partial support has proven hemodynamically efficacious and efficient in relieving heart failure symptoms, improving medical therapy tolerability, and improving quality of life. Unfortunately, the technology was not made available due to financial uncertainty and poor management, but we hope that once the concept has been proved someone will collect the legacy.<\/jats:p>","DOI":"10.1111\/aor.13714","type":"journal-article","created":{"date-parts":[[2020,4,23]],"date-time":"2020-04-23T17:28:43Z","timestamp":1587662923000},"page":"1044-1049","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Single\u2010center experience with partial support device in destination therapy for end\u2010stage heart failure"],"prefix":"10.1111","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5120-5802","authenticated-orcid":false,"given":"Alessandro","family":"Barbone","sequence":"first","affiliation":[{"name":"UO of Cardiac Surgery IRCCS Humanitas Clinical and Research Center Via A. Manzoni 56 Rozzano (Mi) I\u201020089 Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beniamino","family":"Pagliaro","sequence":"additional","affiliation":[{"name":"Heart Failure Division (UO of Cardiology) IRCCS Humanitas Clinical and Research Center Via A. Manzoni 56 Rozzano (Mi) I\u201020089 Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessio","family":"Basciu","sequence":"additional","affiliation":[{"name":"UO of Cardiac Surgery IRCCS Humanitas Clinical and Research Center Via A. Manzoni 56 Rozzano (Mi) I\u201020089 Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandra","family":"Iaccarino","sequence":"additional","affiliation":[{"name":"UO of Cardiac Surgery IRCCS Humanitas Clinical and Research Center Via A. Manzoni 56 Rozzano (Mi) I\u201020089 Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ginevra","family":"Droandi","sequence":"additional","affiliation":[{"name":"UO of Cardiac Surgery IRCCS Humanitas Clinical and Research Center Via A. Manzoni 56 Rozzano (Mi) I\u201020089 Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giorgio","family":"Romano","sequence":"additional","affiliation":[{"name":"UO of Cardiac Surgery IRCCS Humanitas Clinical and Research Center Via A. Manzoni 56 Rozzano (Mi) I\u201020089 Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enrico","family":"Citterio","sequence":"additional","affiliation":[{"name":"UO of Cardiac Surgery IRCCS Humanitas Clinical and Research Center Via A. Manzoni 56 Rozzano (Mi) I\u201020089 Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Fumero","sequence":"additional","affiliation":[{"name":"UO of Cardiac Surgery IRCCS Humanitas Clinical and Research Center Via A. Manzoni 56 Rozzano (Mi) I\u201020089 Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucia","family":"Torracca","sequence":"additional","affiliation":[{"name":"UO of Cardiac Surgery IRCCS Humanitas Clinical and Research Center Via A. Manzoni 56 Rozzano (Mi) I\u201020089 Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniela","family":"Pini","sequence":"additional","affiliation":[{"name":"Heart Failure Division (UO of Cardiology) IRCCS Humanitas Clinical and Research Center Via A. Manzoni 56 Rozzano (Mi) I\u201020089 Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,7,12]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2018.11.011"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2015.07.075"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2006.07.037"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2009.04.023"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2013.01.336"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezt041"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2005.07.016"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1253\/circj.CJ-15-0419"}],"container-title":["Artificial Organs"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Faor.13714","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aor.13714","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/aor.13714","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aor.13714","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,3]],"date-time":"2023-09-03T12:20:04Z","timestamp":1693743604000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/aor.13714"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7,12]]},"references-count":8,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2020,10]]}},"alternative-id":["10.1111\/aor.13714"],"URL":"https:\/\/doi.org\/10.1111\/aor.13714","archive":["Portico"],"relation":{},"ISSN":["0160-564X","1525-1594"],"issn-type":[{"type":"print","value":"0160-564X"},{"type":"electronic","value":"1525-1594"}],"subject":[],"published":{"date-parts":[[2020,7,12]]},"assertion":[{"value":"2020-01-31","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-04-16","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-07-12","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}