{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T17:34:16Z","timestamp":1790098456206,"version":"4.0.1"},"reference-count":37,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2021,3,29]],"date-time":"2021-03-29T00:00:00Z","timestamp":1616976000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Artificial Organs"],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Acute hemodynamic decompensation (AHD) during ventricular tachycardia (VT) ablation occurs in about 11% of cases. Prophylactic use of temporary mechanical circulatory support (pro\u2010tMCS) has been applied to prevent AHD during VT ablation, but evidence supporting this practice is still lacking. This systematic review and meta\u2010analysis assessed the procedural characteristics and outcomes of pro\u2010tMCS for VT ablation. PubMed\/Medline was screened until February 2020. Articles including adults receiving pro\u2010tMCS for VT ablation were included, and a meta\u2010analysis to compare proMCS and no\u2010tMCS was performed. Primary outcome was in\u2010hospital\/30\u2010day mortality. Five observational studies presenting 400 procedures (pro\u2010tMCS: n\u00a0=\u00a0187; no\u2010tMCS: n\u00a0=\u00a0213) were included. Baseline characteristics were comparable between groups. Impella and TandemHeart were used in 86.6% and 13.4% of cases, respectively. In the pro\u2010tMCS group, more VTs were induced (mean difference: 0.52, confidence interval [CI]: 0.26\u20100.77, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.0001), and patients remained in VT on average for 24.04\u00a0minutes longer (CI: 18.28\u201029.80, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.00001). Procedural success was comparable between groups, as was VT recurrence. Pro\u2010tMCS patients had an odds ratio of 0.55 (CI: 0.28\u20101.05, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.07) for in\u2010hospital\/30\u2010day mortality and 0.55 (CI: 0.32\u20100.94, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.03) for mortality at follow\u2010up. Sixty\u2010four percent of no\u2010tMCS patients received rescue tMCS. The most common tMCS\u2010related complications were bleeding events. Pro\u2010tMCS allowed for a prolonged time on VTs and the induction of more VTs. Although these advantages were not associated with differences in procedural success, VT recurrence, or in\u2010hospital\/30\u2010day mortality in the overall population, pro\u2010tMCS might improve long\u2010term survival. Further prospective studies are urgently needed to confirm these results.<\/jats:p>","DOI":"10.1111\/aor.13945","type":"journal-article","created":{"date-parts":[[2021,2,22]],"date-time":"2021-02-22T13:28:04Z","timestamp":1614000484000},"page":"987-997","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Prophylactic mechanical circulatory support for protected ventricular tachycardia ablation: A meta\u2010analysis of the literature"],"prefix":"10.1111","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2238-1399","authenticated-orcid":false,"given":"Silvia","family":"Mariani","sequence":"first","affiliation":[{"name":"Cardio\u2010Thoracic Surgery Department, Heart and Vascular Center Maastricht University Medical Center (MUMC+) Maastricht The Netherlands"},{"name":"Medizinische Hochschule Hannover (MHH)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9945-0842","authenticated-orcid":false,"given":"L. Christian","family":"Napp","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Angiology Hannover Medical School Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8589-5138","authenticated-orcid":false,"given":"Karin","family":"Kraaier","sequence":"additional","affiliation":[{"name":"Department of Cardiology Hart\u2010en Vaatcentrum Leeuwarden, Medical Center Leeuwarden Leeuwarden The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tong","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic, Transplantation and Vascular Surgery Hannover Medical School Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5410-7917","authenticated-orcid":false,"given":"Karl","family":"Bounader","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic, Transplantation and Vascular Surgery Hannover Medical School Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1434-6905","authenticated-orcid":false,"given":"Jasmin S.","family":"Hanke","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic, Transplantation and Vascular Surgery Hannover Medical School Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5984-9426","authenticated-orcid":false,"given":"G\u00fcnes","family":"Dogan","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic, Transplantation and Vascular Surgery Hannover Medical School Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0344-1405","authenticated-orcid":false,"given":"Jan D.","family":"Schmitto","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic, Transplantation and Vascular 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