{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T19:40:45Z","timestamp":1770320445316,"version":"3.49.0"},"reference-count":35,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2021,9,12]],"date-time":"2021-09-12T00:00:00Z","timestamp":1631404800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Artificial Organs"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>End\u2010stage heart failure (ESHF) in pediatric age is an ongoing challenge. Heart transplantation is the final option, but its long\u2010term outcomes are still suboptimal in children. An alternative patient\u2010tailored surgical protocol to manage ESHF in children is described. Retrospective, single\u2010center analysis of pediatric patients admitted to our institution between April 2004 and February 2021 for ESHF. Our current protocol is as follows: (a) Patients &lt;1\u00a0year with isolated left ventricular dysfunction due to dilated cardiomyopathy underwent pulmonary artery banding (PAB). (b) Patients &lt;10\u00a0years and &lt;20\u00a0kg, who did not meet previous criteria were managed with Berlin Heart EXCOR. (c) Patients &gt;10\u00a0years or &gt;20\u00a0kg, underwent placement of intracorporeal Heartware. Primary outcomes were survival, transplant incidence, and postoperative adverse events. A total of 24 patients (mean age 5.3\u00a0\u00b1\u00a05.9\u00a0years) underwent 26 procedures: PAB in 6 patients, Berlin Heart in 11, and Heartware in 7. Two patients shifted from PAB to Berlin Heart. Overall survival at 1\u2010year follow\u2010up and 5\u2010year follow\u2010up was 78.7% (95%CI\u00a0=\u00a062%\u201095.4%) and 74.1% (95%CI\u00a0=\u00a056.1%\u201092.1%), respectively. Berlin Heart was adopted in higher\u2010risk settings showing inferior outcomes, whereas a PAB enabled 67% of patients to avoid transplantation, with no mortality. An integrated, patient\u2010tailored surgical strategy, comprehensive of PAB and different types of ventricular assist devices, can provide satisfactory medium\u2010term results for bridging to transplant or recovery. The early postoperative period is critical and requires strict clinical vigilance. Selected infants can benefit from PAB that has demonstrated to be a safe bridge to recovery.<\/jats:p>","DOI":"10.1111\/aor.14057","type":"journal-article","created":{"date-parts":[[2021,8,30]],"date-time":"2021-08-30T17:35:41Z","timestamp":1630344941000},"page":"1543-1553","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Surgical strategies for the management of end\u2010stage heart failure in infants and children: A 15\u2010year experience with a patient\u2010tailored approach"],"prefix":"10.1111","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4472-6287","authenticated-orcid":false,"given":"Matteo","family":"Ponzoni","sequence":"first","affiliation":[{"name":"Pediatric and Congenital Cardiac Surgery Unit, Department of Cardiac, Thoracic, Vascular Sciences and Public Health University of Padova Medical School Padova Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna C.","family":"Frigo","sequence":"additional","affiliation":[{"name":"Unit of Biostatistics, Department of Cardiac, Thoracic, Vascular Sciences and Public Health University of Padova Medical School Padova Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Biagio","family":"Castaldi","sequence":"additional","affiliation":[{"name":"Pediatric Cardiology Unit, Department of Woman\u2019s and Child\u2019s Health University of Padova Medical School Padova Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessia","family":"Cerutti","sequence":"additional","affiliation":[{"name":"Pediatric Cardiology Unit, Department of Woman\u2019s and Child\u2019s Health University of Padova Medical School Padova Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanni","family":"Di Salvo","sequence":"additional","affiliation":[{"name":"Pediatric Cardiology Unit, Department of Woman\u2019s and Child\u2019s Health University of Padova Medical School Padova Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vladimiro L.","family":"Vida","sequence":"additional","affiliation":[{"name":"Pediatric and Congenital Cardiac Surgery Unit, Department of Cardiac, Thoracic, Vascular Sciences and Public Health University of Padova Medical School Padova Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0343-8118","authenticated-orcid":false,"given":"Massimo A.","family":"Padalino","sequence":"additional","affiliation":[{"name":"Pediatric and Congenital Cardiac Surgery Unit, Department of Cardiac, Thoracic, Vascular Sciences and Public Health University of Padova Medical School Padova 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