{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T19:24:53Z","timestamp":1762543493025,"version":"3.40.5"},"reference-count":28,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2021,9,22]],"date-time":"2021-09-22T00:00:00Z","timestamp":1632268800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Artificial Organs"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Patients with combined circulatory shock and respiratory failure may benefit from veno\u2010arteriovenous (V\u2010AV) extracorporeal membrane oxygenation support (ECMO). We report our center\u2019s experience with V\u2010AV ECMO and propose an algorithm to help identify patients that may benefit from early V\u2010AV ECMO support.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Clinical data were extracted from electronic medical records between November 1, 2016 and November 1, 2019.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Out of a total of 369 patients placed on extracorporeal life support (ECLS), we identified a total of 26 patients who underwent hybrid ECMO placement. Three patients were excluded from our analysis due to veno\u2010venoarterial extracorporeal membrane oxygenation (V\u2010VA ECMO) configuration, therefore 23 patients were included in our analysis. The median age was 53 (range 25\u201373) years. Hybrid ECMO support was instituted most commonly for differential hypoxemia in patients on venoarterial (V\u2010A) ECMO support, and cardiogenic shock in patients who were initially started on venovenous (V\u2010V) ECMO. The initial ECMO cannulation was V\u2010A in 12 patients, V\u2010V in 8 patients, and directly V\u2010AV in 3 patients. Nine out of 23 patients were successfully decannulated (39.1%) and survived until hospital discharge. The main ECMO\u2010related complications included bleeding (<jats:italic>n<\/jats:italic>\u00a0=\u00a010), circuit exchange either due to hemolysis or oxygenator failure (<jats:italic>n<\/jats:italic>\u00a0=\u00a04), ECMO cannula site infection (<jats:italic>n<\/jats:italic>\u00a0=\u00a02), deep venous thrombosis (<jats:italic>n<\/jats:italic>\u00a0=\u00a02), and death during ECMO cannula exchange (<jats:italic>n<\/jats:italic>\u00a0=\u00a01).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>V\u2010AV ECMO represents a rescue strategy in critically ill patients with combined respiratory failure and cardio\u2010circulatory shock.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aor.14070","type":"journal-article","created":{"date-parts":[[2021,9,14]],"date-time":"2021-09-14T07:47:23Z","timestamp":1631605643000},"page":"1554-1561","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Veno\u2010arteriovenous extracorporeal membrane oxygenation\u2014A single center experience"],"prefix":"10.1111","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7334-2891","authenticated-orcid":false,"given":"Mircea R.","family":"Mihu","sequence":"first","affiliation":[{"name":"Advanced Critical Care Nazih Zuhdi Transplant Institute, Advanced Cardiac Care and 24\/7 Shock Service, Integris Baptist Medical Center Oklahoma City Oklahoma USA"},{"name":"Department of Medicine\/Cardiology Oklahoma State University Health Science Center Tulsa Oklahoma USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dennis","family":"Mageka","sequence":"additional","affiliation":[{"name":"Advanced Critical Care Nazih Zuhdi Transplant Institute, Advanced Cardiac Care and 24\/7 Shock Service, Integris Baptist Medical Center Oklahoma City Oklahoma USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura V.","family":"Swant","sequence":"additional","affiliation":[{"name":"Advanced Critical Care Nazih Zuhdi Transplant Institute, Advanced Cardiac Care and 24\/7 Shock Service, Integris Baptist Medical Center Oklahoma City Oklahoma USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed","family":"El Banayosy","sequence":"additional","affiliation":[{"name":"Advanced Critical Care Nazih Zuhdi Transplant Institute, Advanced Cardiac Care and 24\/7 Shock Service, Integris Baptist Medical Center Oklahoma City Oklahoma USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marc O.","family":"Maybauer","sequence":"additional","affiliation":[{"name":"Advanced Critical Care Nazih Zuhdi Transplant Institute, Advanced Cardiac Care and 24\/7 Shock Service, Integris Baptist Medical Center Oklahoma City Oklahoma USA"},{"name":"Department of Medicine\/Cardiology Oklahoma State University Health Science Center Tulsa Oklahoma USA"},{"name":"Department of Anesthesiology and Intensive Care Medicine Philipps University Marburg Germany"},{"name":"Critical Care Research Group The Prince Charles Hospital The University of Queensland Brisbane Queensland Australia"},{"name":"Department of Anaesthesia Manchester University NHS Foundation Trust University of Manchester Manchester Health Science Center Manchester UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael D.","family":"Harper","sequence":"additional","affiliation":[{"name":"Advanced Critical Care Nazih Zuhdi Transplant Institute, Advanced Cardiac Care and 24\/7 Shock Service, Integris Baptist Medical Center Oklahoma City Oklahoma USA"},{"name":"Department of Medicine\/Cardiology Oklahoma State University Health Science Center Tulsa Oklahoma USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael M.","family":"Koerner","sequence":"additional","affiliation":[{"name":"Department of Medicine\/Cardiology Oklahoma State University Health Science Center Tulsa Oklahoma USA"},{"name":"Faculty of Medicine Ruhr\u2010University Bochum Germany"},{"name":"Department of Medicine\/Cardiology Baylor, Scott &amp; 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