{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T17:10:48Z","timestamp":1792084248867,"version":"4.4.0"},"reference-count":27,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2021,11,23]],"date-time":"2021-11-23T00:00:00Z","timestamp":1637625600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2021,11,23]],"date-time":"2021-11-23T00:00:00Z","timestamp":1637625600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","award":["CM19\/00055"],"award-info":[{"award-number":["CM19\/00055"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Artificial Organs"],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Age over 70\u00a0years seems to confer poor prognosis for patients under mechanical circulatory support (MCS). Advanced age is usually a relative contraindication. Our objective was to assess the impact of age on survival of patients with short\u2010term MCS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Retrospective analysis of \u226570\u2010year\u2010old patients supported with veno\u2010arterial extracorporeal membrane oxygenation (VA\u2010ECMO) or Impella CP\u00ae due to cardiogenic shock and other situations of hemodynamic instability in a referral hospital (elderly group), compared with younger patients (&lt;70\u00a0years). We analyze factors associated with survival in elderly group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Out of 164 short\u2010term MCS implants from 2013 to October 2020, 45 (27.4%) correspond to \u226570\u2010year\u2010old patients (73.3% VA\u2010ECMO; 26.7% Impella CP\u00ae), 80% as bridge to recovery and 15.6% for high\u2010risk percutaneous coronary intervention (PCI). We found no significant differences in complications developed between both groups. Survivals at discharge (40% vs. 43.7%,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.403) and at follow\u2010up (median 13.6 [30] months) were similar in elderly and young patients (35.6% vs. 37.8%, log\u2010rank\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.061). Predictive factors of mortality in elderly patients were peripheral artery disease (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.037), higher lactate (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.003) and creatinine (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.035) at implant, longer cardiac arrest (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.003), and worse post\u2010implantation left ventricular ejection fraction (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.003). Patients with indication of MCS for high\u2010risk PCI had higher survival compared to other indications (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.013).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Short\u2010term MCS with VA\u2010ECMO or Impella CP\u00ae in elderly patients may be a reasonable option in hemodynamic compromise situations as bridge to recovery or elective high\u2010risk PCI, without a significant increase in complications or mortality. Age should not be an absolute contraindication, but careful selection of candidate patients is necessary.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/aor.14117","type":"journal-article","created":{"date-parts":[[2021,11,15]],"date-time":"2021-11-15T10:22:15Z","timestamp":1636971735000},"page":"867-877","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Short\u2010term mechanical circulatory support in elderly patients"],"prefix":"10.1111","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4363-8835","authenticated-orcid":false,"given":"Marta","family":"Alonso\u2010Fernandez\u2010Gatta","sequence":"first","affiliation":[{"name":"Cardiology Department University Hospital of Salamanca, IBSAL  Salamanca Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soraya","family":"Merchan\u2010Gomez","sequence":"additional","affiliation":[{"name":"Cardiology Department University Hospital of Salamanca, IBSAL  Salamanca Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ines","family":"Toranzo\u2010Nieto","sequence":"additional","affiliation":[{"name":"Cardiology Department University Hospital of Salamanca, IBSAL  Salamanca Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miryam","family":"Gonzalez\u2010Cebrian","sequence":"additional","affiliation":[{"name":"Cardiology Department University Hospital of Salamanca, IBSAL  Salamanca Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alejandro","family":"Diego\u2010Nieto","sequence":"additional","affiliation":[{"name":"Cardiology Department University Hospital of Salamanca, IBSAL  Salamanca Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfredo","family":"Barrio","sequence":"additional","affiliation":[{"name":"Cardiology Department University Hospital of Salamanca, IBSAL  Salamanca Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco","family":"Martin\u2010Herrero","sequence":"additional","affiliation":[{"name":"Cardiology Department University Hospital of Salamanca, IBSAL  Salamanca Spain"},{"name":"CIBER\u2010CV Instituto de Salud Carlos III (ISCIII)  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro L.","family":"Sanchez","sequence":"additional","affiliation":[{"name":"Cardiology Department University Hospital of Salamanca, IBSAL  Salamanca Spain"},{"name":"CIBER\u2010CV Instituto de Salud Carlos III (ISCIII)  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,11,23]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11886-018-1041-4"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2015.03.036"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2019.12.021"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.119.034512"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAT.0000000000000475"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2016.10.023"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000003631"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2020.09.044"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2019.04.063"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-011-2358-2"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCHEARTFAILURE.116.003179"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehv194"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-019-2307-y"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-016-4223-9"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2018.03.024"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1177\/2048872618805486"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-019-2368-y"},{"key":"e_1_2_9_19_1","volume-title":"ELSO 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