{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,8]],"date-time":"2026-08-08T02:45:06Z","timestamp":1786157106188,"version":"build-2736575974"},"reference-count":34,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2021,12,26]],"date-time":"2021-12-26T00:00:00Z","timestamp":1640476800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2021,12,26]],"date-time":"2021-12-26T00:00:00Z","timestamp":1640476800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Artificial Organs"],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Cardiopulmonary bypass (CPB) during left ventricular assist device (LVAD) implantation provides circulatory support and allows for safe inspection of the left ventricle (LV), whereas circulatory support by veno\u2010arterial extracorporeal life support (va\u2010ECLS) or off\u2010pump implantation may reduce postoperative bleeding and inflammatory response.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Retrospective analysis of 616\u00a0consecutive adult patients who received an LVAD via median sternotomy between January 1, 2015 and December 31, 2019. All patients undergoing concomitant intracardiac procedures other than closure of persistent foramen ovale or atrial septal defect and redo surgeries were excluded from the analysis. The remaining patients (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a0222) were divided into two groups and 1:1 propensity score\u2010matched regarding preoperative parameters: patients who underwent LVAD implantation with LV inspection employing CPB (CPB group,\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a062) and without LV inspection on va\u2010ECLS or off\u2010pump (non\u2010CPB group,\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a062).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The groups were well balanced with regard to preoperative baseline characteristics (standard difference &lt;0.1). Patients in the CPB group required more blood transfusions (median 2 vs. 0 units,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.031) during surgery and in the first 24\u00a0h afterwards. The median intensive care unit stay was longer in the CPB group (18 vs. 11\u00a0days,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.021). The CPB group showed an absence of perioperative stroke and a smaller number of events per patient\u2010year for postoperative ischemic stroke (0.02 vs. 0.12,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.003). 30\u2010day survival (87% vs. 87.1%) and 1\u2010year survival (80.3% vs. 74%) were similar in both groups (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.78).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Visual LV inspection on CPB may reduce the risk of postoperative ischemic stroke. Despite the negative effects of employing CPB in lieu of other intraoperative strategies, survival was similar in both groups.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/aor.14145","type":"journal-article","created":{"date-parts":[[2021,12,14]],"date-time":"2021-12-14T01:45:48Z","timestamp":1639446348000},"page":"908-921","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Impact of left ventricular inspection employing cardiopulmonary bypass on outcome after implantation of left ventricular assist device"],"prefix":"10.1111","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9831-6289","authenticated-orcid":false,"given":"Daniel","family":"Lewin","sequence":"first","affiliation":[{"name":"Department of Cardiothoracic and Vascular Surgery German Heart Center Berlin  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9524-7705","authenticated-orcid":false,"given":"Gaik","family":"Nersesian","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic and Vascular Surgery German Heart Center Berlin  Berlin Germany"},{"name":"DZHK (German Centre for Cardiovascular Research), partner site Berlin  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8826-075X","authenticated-orcid":false,"given":"Luise","family":"Roehrich","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic and Vascular Surgery German Heart Center Berlin  Berlin Germany"},{"name":"DZHK (German Centre for Cardiovascular Research), partner site Berlin  Berlin Germany"},{"name":"German Heart Foundation  Frankfurt am Main 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Heart Center Berlin  Berlin Germany"},{"name":"DZHK (German Centre for Cardiovascular Research), partner site Berlin  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7911-8620","authenticated-orcid":false,"given":"Volkmar","family":"Falk","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic and Vascular Surgery German Heart Center Berlin  Berlin Germany"},{"name":"DZHK (German Centre for Cardiovascular Research), partner site Berlin  Berlin Germany"},{"name":"Department of Cardiovascular Surgery Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin, Corporate Member of Freie Universit\u00e4t Berlin, Humboldt\u2010Universit\u00e4t zu Berlin  Berlin Germany"},{"name":"Berlin Institute of Health (BIH)  Berlin Germany"},{"name":"Translational Cardiovascular Technologies Department of Health Sciences and Technology Institute of Translational Medicine Swiss Federal Institute of Technology (ETH) Zurich  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