{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T15:15:00Z","timestamp":1791645300800,"version":"4.3.4"},"reference-count":20,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2022,1,20]],"date-time":"2022-01-20T00:00:00Z","timestamp":1642636800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2022,1,20]],"date-time":"2022-01-20T00:00:00Z","timestamp":1642636800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Artificial Organs"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Extracorporeal membrane oxygenation or extracorporeal life support (ECLS) in patients after cardiac surgery and postcardiotomy cardiogenic shock (PCS) is known to be associated with high mortality. Especially in patients after coronary artery bypass grafting (CABG) and PCS, ECLS is frequently established. The aim of this analysis was to evaluate factors associated with in\u2010hospital mortality in patients treated with ECLS due to PCS after CABG.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Between August 2006 and January 2017, 92 consecutive patients with V\u2010A ECLS due to PCS after isolated CABG were identified and included in this retrospective analysis. Patients were divided into survivors (S) and non\u2010survivors (NS) and analyzed with risk factors of in\u2010hospital mortality.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In\u2010hospital mortality added up to 61 patients (66%). Non\u2010survivors were significantly older (60\u00a0\u00b1\u00a0812 (S) vs. 67\u00a0\u00b1\u00a010 (NS);\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.013). Bilateral internal mammary artery graft was significantly more frequently used in S (23% (S) vs. 2% (NS);\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.001). After 24\u00a0h of ECLS support, median lactate levels were significantly higher in NS (1.9 (1.3; 3.5) mmol\/L (S) vs. 3.5 (2.1; 6.3) mmol\/L (NS);\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.001). NS suffered more often acute kidney injury requiring dialysis (42% (S) vs. 74% (NS);\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.002).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Mortality in patients with refractory PCS after CABG and consecutive ECLS support remains high. Failing end\u2010organ recovery under ECLS despite optimized concomitant medical therapy is an indicator of adverse outcomes in this specific patient cohort. Moreover, total\u2010arterial revascularization might be beneficial for cardiac recovery in patients suffering PCS after CABG and following ECLS.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/aor.14166","type":"journal-article","created":{"date-parts":[[2022,1,5]],"date-time":"2022-01-05T08:16:41Z","timestamp":1641370601000},"page":"1158-1164","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Risk factors associated with in\u2010hospital mortality for patients with ECLS due to postcardiotomy cardiogenic shock after isolated coronary surgery"],"prefix":"10.1111","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2178-8397","authenticated-orcid":false,"given":"Christian J\u00f6rg","family":"Rustenbach","sequence":"first","affiliation":[{"name":"Department of Cardiothoracic Surgery University Hospital Cologne  Cologne Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5810-8626","authenticated-orcid":false,"given":"Ilija","family":"Djordjevic","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery University Hospital Cologne  Cologne Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lara","family":"David","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery University Hospital Cologne  Cologne Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8052-8232","authenticated-orcid":false,"given":"Borko","family":"Ivanov","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery University Hospital Cologne  Cologne Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen","family":"Gerfer","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery University Hospital Cologne  Cologne Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7232-3330","authenticated-orcid":false,"given":"Christopher","family":"Gaisendrees","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery University Hospital Cologne  Cologne Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefanie","family":"Wendt","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery University Hospital Cologne  Cologne Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4490-8937","authenticated-orcid":false,"given":"Julia","family":"Merkle","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery University Hospital Cologne  Cologne 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