{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T16:18:09Z","timestamp":1787242689451,"version":"build-2736575974"},"reference-count":31,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2022,9,27]],"date-time":"2022-09-27T00:00:00Z","timestamp":1664236800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Artificial Organs"],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Peripartum cardiomyopathy (PPCM) is a rare cause of heart failure (HF), presenting with left ventricular (LV) systolic dysfunction either at the end of pregnancy or in the months following delivery. In rare cases, PPCM leads to severe impairment of LV function, refractory cardiogenic shock or advanced HF. LV assist devices (LVAD) have been shown to be a feasible treatment option in advanced HF. However, little is known about long\u2010term outcomes and prognosis of PPCM patients undergoing LVAD implantation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective analysis of data from PPCM patients undergoing LVAD implantation in two tertiary centers with respect to long\u2010term outcomes was performed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Twelve patients of median age 30 (18\u201339) years were included. Eight patients were experiencing cardiogenic shock (INTERMACS 1) at implantation. Seven patients were implanted within 1 month of their PPCM diagnosis. Median duration of LVAD support was 19 (2\u201392) months with median follow up of 67 (18\u2013136) months (100% complete). In\u2010hospital and 1\u2010year mortality were 0% and 8.3%, respectively. Two patients died on LVAD support, four patients were successfully bridged to transplantation, two patients are still on LVAD, and four were successfully weaned due to sufficient LV recovery (one died after LV function deteriorated again).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>LVAD treatment of decompensated end\u2010stage PPCM is feasible. Early LVAD provision led to hemodynamic stabilization in our cohort and facilitated safe LV recovery in one third of these young female patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/aor.14406","type":"journal-article","created":{"date-parts":[[2022,9,16]],"date-time":"2022-09-16T20:58:00Z","timestamp":1663361880000},"page":"417-424","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Clinical characteristics and long\u2010term outcomes in patients with peripartum cardiomyopathy (\n                    <scp>PPCM<\/scp>\n                    ) receiving left ventricular assist devices (\n                    <scp>LVAD<\/scp>\n                    )"],"prefix":"10.1111","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5710-3540","authenticated-orcid":false,"given":"Dominik","family":"Berliner","sequence":"first","affiliation":[{"name":"Department of Cardiology and Angiology Hannover Medical School  Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2041-5823","authenticated-orcid":false,"given":"Tong","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Cardiac, Thoracic, Transplant and Vascular Surgery Hannover Medical School  Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2238-1399","authenticated-orcid":false,"given":"Silvia","family":"Mariani","sequence":"additional","affiliation":[{"name":"Department of Cardiac, Thoracic, Transplant and Vascular Surgery Hannover Medical School  Hannover Germany"},{"name":"Department of Cardio\u2010Thoracic Surgery, Heart and Vascular Centre Maastricht University Medical Centre (MUMC+)  Maastrichts The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6206-4139","authenticated-orcid":false,"given":"Righab","family":"Hamdan","sequence":"additional","affiliation":[{"name":"Department of Cardiology Beirut Cardiac Institute  Beirut Lebanon"},{"name":"Al Qassimi Hospital University of Sharjah  Sharjah United Arab Emirates"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1434-6905","authenticated-orcid":false,"given":"Jasmin","family":"Hanke","sequence":"additional","affiliation":[{"name":"Department of Cardiac, Thoracic, Transplant and Vascular Surgery Hannover Medical School  Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tobias","family":"K\u00f6nig","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Angiology Hannover Medical School  Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tobias Jonathan","family":"Pfeffer","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Angiology Hannover Medical School  Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valeska","family":"Abou\u2010Moulig","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Angiology Hannover Medical School  Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5984-9426","authenticated-orcid":false,"given":"G\u00fcnes","family":"Dogan","sequence":"additional","affiliation":[{"name":"Department of Cardiac, Thoracic, Transplant and Vascular Surgery Hannover Medical School  Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denise","family":"Hilfiker\u2010Kleiner","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Angiology Hannover Medical School  Hannover Germany"},{"name":"Department of Cardiovascular Complications in Pregnancy and in Oncologic Therapies, Comprehensive Cancer Center Philipps University Marburg  Marburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Axel","family":"Haverich","sequence":"additional","affiliation":[{"name":"Department of Cardiac, Thoracic, Transplant and Vascular Surgery Hannover Medical School  Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johann","family":"Bauersachs","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Angiology Hannover Medical School  Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan D.","family":"Schmitto","sequence":"additional","affiliation":[{"name":"Department of Cardiac, Thoracic, Transplant and Vascular Surgery Hannover Medical School  Hannover 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