{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T12:06:44Z","timestamp":1780402004034,"version":"3.54.1"},"reference-count":20,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2023,4,7]],"date-time":"2023-04-07T00:00:00Z","timestamp":1680825600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Artificial Organs"],"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The incidence of nephrolithiasis in kidney donors is rare. The timing and treatment of nephrolithiasis in deceased donor kidneys are not well established. While some programs have proposed ex\u2010situ rigid or flexible ureteroscopy treatment before transplantation, we report on two cases of kidney stones in the same deceased donor that we treated by flexible ureteroscopy and laser lithotripsy performed during the storage time on a hypothermic perfusion machine. Two deceased donor kidneys were found to have multiple kidney stones discovered on preprocurement CT imaging. The right kidney had less than five 2\u20133\u2009mm stones, whereas the left had five to ten 1\u2009mm stones with a single 7\u2009mm stone. Both organs were placed on a hypothermic perfusion machine and maintained at a temperature of 4\u00b0C. An ex\u2010vivo flexible ureteroscopy with laser lithotripsy and basket extraction was performed while the kidneys were maintained on Lifeport* perfusion machine. The cold ischemia time was 16.9 and 23.1\u2009h. After 12 months of observational follow\u2010up, neither recipient had nephrolithiasis, UTI, or other urologic complications. The creatinine values now are 1.17 and 2.44\u2009mg\/dL (103.4 and 215.7\u2009\u03bcmol\/L), respectively. Ex\u2010vivo flexible ureteroscopy with laser lithotripsy and stone removal on machine\u2010perfused kidneys appears to be safe and offers a good option to treat graft nephrolithiasis and prevent posttransplant complications. Ureteroscopy serves as a minimally invasive treatment option with direct stone removal. Performing this while on machine perfusion minimizes the ischemic time of the kidney and resultant complications or delays in graft function.<\/jats:p>","DOI":"10.1111\/aor.14528","type":"journal-article","created":{"date-parts":[[2023,4,7]],"date-time":"2023-04-07T09:56:31Z","timestamp":1680861391000},"page":"1214-1222","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Ex\u2010vivo ureteroscopy, laser lithotripsy, and stone basketing extraction of deceased donor kidney stones during machine perfusion preservation"],"prefix":"10.1111","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6251-3598","authenticated-orcid":false,"given":"Gregory","family":"Kunkel","sequence":"first","affiliation":[{"name":"Department of Urology, University of Massachusetts Memorial Hospital University of Massachusetts  Worcester Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Igor","family":"Sorokin","sequence":"additional","affiliation":[{"name":"Department of Urology, University of Massachusetts Memorial Hospital University of Massachusetts  Worcester Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michela","family":"Oster","sequence":"additional","affiliation":[{"name":"Division of Organ Transplantation, Department of Surgery University of Massachusetts Memorial Hospital, University of Massachusetts  Worcester Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"Van\u00a0Horn","sequence":"additional","affiliation":[{"name":"Department of Urology, University of Massachusetts Memorial Hospital University of Massachusetts  Worcester Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Babak","family":"Movahedi","sequence":"additional","affiliation":[{"name":"Division of Organ Transplantation, Department of Surgery University of Massachusetts Memorial Hospital, University of Massachusetts  Worcester Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fan","family":"Pang\u2010Yen","sequence":"additional","affiliation":[{"name":"Division of Transplant Nephrology, Department of Medicine University of Massachusetts Memorial Hospital, University of Massachusetts  Worcester Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9333-0233","authenticated-orcid":false,"given":"Paulo N.","family":"Martins","sequence":"additional","affiliation":[{"name":"Division of Organ Transplantation, Department of Surgery University of Massachusetts Memorial Hospital, University of Massachusetts  Worcester Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,4,7]]},"reference":[{"key":"e_1_2_10_2_1","unstructured":"Organ Procurement and Transplantation Network.2022. 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