{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T09:07:09Z","timestamp":1785575229984,"version":"3.56.0"},"reference-count":17,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2023,4,25]],"date-time":"2023-04-25T00:00:00Z","timestamp":1682380800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2023,4,25]],"date-time":"2023-04-25T00:00:00Z","timestamp":1682380800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Artificial Organs"],"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Post\u2010acute myocardial infarction papillary muscle rupture (post\u2010AMI PMR) may present variable clinical scenarios and degree of emergency due to result of cardiogenic shock. Veno\u2010arterial extracorporeal life support (V\u2010A ECLS) has been proposed to improve extremely poor pre\u2010 or postoperative conditions. Information in this respect is scarce.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>From the CAUTION (meChanical complicAtion of acUte myocardial infarcTion: an InternatiOnal multiceNter cohort study) database (16 different Centers, data from 2001 to 2018), we extracted adult patients who were surgically treated for post\u2010AMI PMR and underwent pre\u2010 or\/and postoperative V\u2010A ECLS support. The end\u2010points of this study were in\u2010hospital survival and ECLS complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>From a total of 214 post\u2010AMI PMR patients submitted to surgery, V\u2010A ECLS was instituted in 23 (11%) patients. The median age was 61.7\u2009years (range 46\u201381\u2009years). Preoperatively, ECLS was commenced in 10 patients (43.5%), whereas intra\/postoperative in the remaining 13. The most common V\u2010A ECLS indication was post\u2010cardiotomy shock, followed by preoperative cardiogenic shock and cardiac arrest. The median duration of V\u2010A ECLS was 4\u2009days. V\u2010A ECLS complications occurred in more than half of the patients. Overall, in\u2010hospital mortality was 39.2% (9\/23), compared to 22% (42\/219) for the non\u2010ECLS group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In post\u2010AMI PMR patients, V\u2010A ECLS was used in almost 10% of the patients either to promote bridge to surgery or as postoperative support. Further investigations are required to better evaluate a potential for increased use and its effects of V\u2010A ECLS in such a context based on the still high perioperative mortality.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/aor.14541","type":"journal-article","created":{"date-parts":[[2023,4,11]],"date-time":"2023-04-11T11:10:10Z","timestamp":1681211410000},"page":"1386-1394","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Extracorporeal life support in mitral papillary muscle rupture: Outcome of multicenter study"],"prefix":"10.1111","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9278-1144","authenticated-orcid":false,"given":"Giulio","family":"Massimi","sequence":"first","affiliation":[{"name":"Department of Cardiothoracic Surgery, Heart and Vascular Centre Maastricht University Medical Centre  Maastricht The Netherlands"},{"name":"Department of Cardiac Surgery Santa Maria della Misericordia Hospital  Perugia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matteo","family":"Matteucci","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Heart and Vascular Centre Maastricht University Medical Centre  Maastricht The Netherlands"},{"name":"Department Biotechnology and Life Sciences Insubria University\u2010 Cardiac Anaesthesia and Intensive Care ASST Sette Laghi Circolo Hospital  Varese Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele","family":"De\u00a0Bonis","sequence":"additional","affiliation":[{"name":"Cardiothoracic Surgery Department San Raffaele University Hospital  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariusz","family":"Kowalewski","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Heart and Vascular Centre Maastricht University Medical Centre  Maastricht The Netherlands"},{"name":"Thoracic Research Centre, Collegium Medicum Nicolaus Copernicus University, Innovative Medical Forum  Bydgoszcz Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3989-6134","authenticated-orcid":false,"given":"Francesco","family":"Formica","sequence":"additional","affiliation":[{"name":"Department of Medicine and Surgery, Cardiac Surgery Clinic San Gerardo Hospital, University of Milano\u2010Bicocca  Monza Italy"},{"name":"Department of Medicine and Surgery University of Parma  Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudio Francesco","family":"Russo","sequence":"additional","affiliation":[{"name":"Cardiac Surgery Unit, Cardio\u2010Thoraco\u2010Vascular Department Niguarda Hospital  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandro","family":"Sponga","sequence":"additional","affiliation":[{"name":"Cardiothoracic Department University Hospital of Udine  Udine Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Igor","family":"Vendramin","sequence":"additional","affiliation":[{"name":"Cardiothoracic Department University Hospital of Udine  Udine Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Colli","sequence":"additional","affiliation":[{"name":"Section of Cardiac Surgery University Hospital  Pisa Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giosu\u00e8","family":"Falcetta","sequence":"additional","affiliation":[{"name":"Section of Cardiac Surgery University Hospital  Pisa Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cinzia","family":"Trumello","sequence":"additional","affiliation":[{"name":"Cardiothoracic Surgery Department San Raffaele University Hospital  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5506-0201","authenticated-orcid":false,"given":"Massimiliano","family":"Carrozzini","sequence":"additional","affiliation":[{"name":"Cardiac Surgery Unit, Cardio\u2010Thoraco\u2010Vascular Department Niguarda Hospital  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theodor","family":"Fischlein","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Cardiovascular Center, Klinikum N\u00fcrnberg Paracelsus Medical University  Nuremberg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni","family":"Troise","sequence":"additional","affiliation":[{"name":"Cardiac Surgery Unit Poliambulanza Foundation Hospital  Brescia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4209-2866","authenticated-orcid":false,"given":"Guglielmo","family":"Actis\u00a0Dato","sequence":"additional","affiliation":[{"name":"Cardiac Surgery Department Mauriziano Hospital  Turin Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"D'Alessandro","sequence":"additional","affiliation":[{"name":"Department of Medicine and Surgery, Cardiac Surgery Clinic San Gerardo Hospital, University of Milano\u2010Bicocca  Monza Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peyman","family":"Sardari Nia","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Heart and Vascular Centre Maastricht University Medical Centre  Maastricht The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vittoria","family":"Lodo","sequence":"additional","affiliation":[{"name":"Cardiac Surgery Department Mauriziano Hospital  Turin Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3446-7832","authenticated-orcid":false,"given":"Emmanuel","family":"Villa","sequence":"additional","affiliation":[{"name":"Cardiac Surgery Unit Poliambulanza Foundation Hospital  Brescia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shabir Hussain","family":"Shah","sequence":"additional","affiliation":[{"name":"Cardiovascular and Thoracic Surgery Department King Fahad Medical City  Riyadh Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Scrofani","sequence":"additional","affiliation":[{"name":"Cardiac Surgery Unit Policlinico Milano Hospital  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irene","family":"Binaco","sequence":"additional","affiliation":[{"name":"Cardiac Surgery Unit Policlinico Milano Hospital  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jurij Matija","family":"Kalisnik","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Cardiovascular Center, Klinikum N\u00fcrnberg Paracelsus Medical University  Nuremberg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matteo","family":"Pettinari","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery Ziekenhuis Oost\u2010Limburg  Genk Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Thielmann","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery, West\u2010German Heart Center University of Duisburg\u2010Essen  Essen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bart","family":"Meyns","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery University Hospitals Leuven  Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fareed A.","family":"Khouqeer","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery King Faisal Specialist Hospital and Research Center  Riyadh Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlo","family":"Fino","sequence":"additional","affiliation":[{"name":"Cardiovascular Department Papa Giovanni XXIII Hospital  Bergamo Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caterina","family":"Simon","sequence":"additional","affiliation":[{"name":"Cardiovascular Department Papa Giovanni XXIII Hospital  Bergamo Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Severgnini","sequence":"additional","affiliation":[{"name":"Department Biotechnology and Life Sciences Insubria University\u2010 Cardiac Anaesthesia and Intensive Care ASST Sette Laghi Circolo Hospital  Varese 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