{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T13:57:04Z","timestamp":1790085424720,"version":"4.0.1"},"reference-count":31,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2023,5,10]],"date-time":"2023-05-10T00:00:00Z","timestamp":1683676800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Artificial Organs"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To perform a systematic review and meta\u2010analysis of the techniques and outcomes associated with percutaneous decannulation of venoarterial extracorporeal membrane oxygenation (VA\u2013ECMO) using the Manta vascular closure device.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>Peripheral VA\u2013ECMO can be used to treat critically ill patients with conditions such as refractory cardiogenic shock. After percutaneous implantation of VA\u2013ECMO, VA\u2013ECMO can also be decannulated completely percutaneously by using a vascular closure device. The Manta vascular closure device is a dedicated device used in the closure of large\u2010bore arteriotomies by sandwiching the arteriotomy with an intra\u2010arterial toggle and an extraluminal collagen plug.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We performed a thorough literature search using various electronic databases. We included studies that reported outcomes after peripheral femorofemoral VA\u2013ECMO decannulation with the Manta vascular closure device. We performed a meta\u2010analysis of proportions on outcome measures, including technical success, bleeding complications, vascular complications, wound complications, major amputation, and procedural\u2010related deaths.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We included seven studies with a total of 116 patients. The overall technical success of percutaneous decannulation of VA\u2013ECMO with the Manta vascular closure device was 93.7%. The overall incidence of bleeding, vascular and wound complications was 1.7%, 13.8%, and 3.4%, respectively. No patient required lower limb amputation or died due to VA\u2013ECMO decannulation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Percutaneous decannulation with the Manta vascular closure device is an effective and safe procedure that should be considered in suitable patients on VA\u2013ECMO.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aor.14554","type":"journal-article","created":{"date-parts":[[2023,5,11]],"date-time":"2023-05-11T02:45:21Z","timestamp":1683773121000},"page":"1431-1441","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Percutaneous decannulation of venoarterial extracorporeal membrane oxygenation using the Manta vascular closure device: A systematic review and meta\u2010analysis"],"prefix":"10.1111","volume":"47","author":[{"given":"Jun Jie","family":"Ng","sequence":"first","affiliation":[{"name":"Division of Vascular and Endovascular Surgery, Department of Cardiac, Thoracic and Vascular Surgery National University Heart Centre  Singapore Singapore"},{"name":"Department of Surgery, Yong Loo Lin School of Medicine National University of Singapore  Singapore Singapore"},{"name":"SingVaSC, Singapore Vascular Surgical Collaborative  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefanie H. T.","family":"Lee","sequence":"additional","affiliation":[{"name":"SingVaSC, Singapore Vascular Surgical Collaborative  Singapore Singapore"},{"name":"Yong Loo Lin School of Medicine National University of Singapore  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2906-2550","authenticated-orcid":false,"given":"Joseph K. W.","family":"Lim","sequence":"additional","affiliation":[{"name":"Division of Vascular and Endovascular Surgery, Department of Cardiac, Thoracic and Vascular Surgery National University Heart Centre  Singapore Singapore"},{"name":"SingVaSC, Singapore Vascular Surgical Collaborative  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen K. W.","family":"Chan","sequence":"additional","affiliation":[{"name":"Division of Vascular and Endovascular Surgery, Department of Cardiac, Thoracic and Vascular Surgery National University Heart Centre  Singapore Singapore"},{"name":"Department of Surgery, Yong Loo Lin School of Medicine National University of Singapore  Singapore Singapore"},{"name":"SingVaSC, Singapore Vascular Surgical Collaborative  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark D. S.","family":"Lim","sequence":"additional","affiliation":[{"name":"Division of Vascular and Endovascular Surgery, Department of Cardiac, Thoracic and Vascular Surgery National University Heart Centre  Singapore Singapore"},{"name":"SingVaSC, Singapore Vascular Surgical Collaborative  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed A. I.","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Division of Vascular and Endovascular Surgery, Department of Cardiac, Thoracic and Vascular Surgery National University Heart Centre  Singapore Singapore"},{"name":"SingVaSC, Singapore Vascular Surgical Collaborative  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stanley E. K.","family":"Loh","sequence":"additional","affiliation":[{"name":"SingVaSC, Singapore Vascular Surgical Collaborative  Singapore Singapore"},{"name":"Department of Diagnostic Radiology Woodlands Health Campus  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew M. T. L.","family":"Choong","sequence":"additional","affiliation":[{"name":"Division of Vascular and Endovascular Surgery, Department of Cardiac, Thoracic and Vascular Surgery National University Heart Centre  Singapore Singapore"},{"name":"Department of Surgery, Yong Loo Lin School of Medicine National University of Singapore  Singapore Singapore"},{"name":"SingVaSC, Singapore Vascular Surgical Collaborative  Singapore Singapore"},{"name":"Cardiovascular Research Institute National University of Singapore  Singapore 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