{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T09:48:12Z","timestamp":1787737692182,"version":"build-2784847793"},"reference-count":20,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2023,6,19]],"date-time":"2023-06-19T00:00:00Z","timestamp":1687132800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2023,6,19]],"date-time":"2023-06-19T00:00:00Z","timestamp":1687132800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Artificial Organs"],"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Little is known about safety and efficacy of the use of Impella 5.5 compared to previous iterations in the setting of Impella with Veno\u2010Arterial Extracorporeal Membrane Oxygenation Support as ECPELLA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Consecutive patients who were treated by ECPELLA with surgically implanted axillary Impella 5.5 (\n                      <jats:italic>N<\/jats:italic>\n                      = 13) were compared with patients supported by ECPELLA with percutaneous femoral Impella CP or 2.5 (Control,\n                      <jats:italic>N<\/jats:italic>\n                      = 13).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The total ECPELLA flow was higher in ECPELLA 5.5 group (6.9 vs. 5.4 L\/min,\n                      <jats:italic>p<\/jats:italic>\n                      = 0.019). Actual hospital survival was higher than predicted and comparable in both groups (ECPELLA 5.5, 61.5% vs. Control, 53.8%,\n                      <jats:italic>p<\/jats:italic>\n                      = 0.691). Both total device complications (ECPELLA 5.5, 7.7% vs. Control, 46.1%,\n                      <jats:italic>p<\/jats:italic>\n                      = 0.021) and Impella\u2010specific complications (ECPELLA 5.5, 0% vs. Control, 30.8%,\n                      <jats:italic>p<\/jats:italic>\n                      = 0.012) were significantly lower in the ECPELLA 5.5 group.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Utilization of Impella 5.5 in the setting of ECPELLA provides greater hemodynamic support with a lower risk of complications compared to Impella CP or 2.5.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/aor.14594","type":"journal-article","created":{"date-parts":[[2023,6,19]],"date-time":"2023-06-19T13:19:01Z","timestamp":1687180741000},"page":"1404-1412","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Evolution of concomitant use of veno\u2010arterial extracorporeal membrane oxygenation support with Impella in cardiogenic shock: From percutaneous femoral Impella to axillary Impella 5.5"],"prefix":"10.1111","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7992-8113","authenticated-orcid":false,"given":"Ameesh","family":"Isath","sequence":"first","affiliation":[{"name":"Department of Cardiology Westchester Medical Center and New York Medical College  Valhalla New York 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