{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T23:08:37Z","timestamp":1791068917833,"version":"4.1.0"},"reference-count":46,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2023,7,7]],"date-time":"2023-07-07T00:00:00Z","timestamp":1688688000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Artificial Organs"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Mobilization is important in longer courses in intensive care unit (ICU), typical for patients requiring venovenous extracorporeal membrane oxygenation (V\u2010V ECMO). For patients supported with ECMO, especially out\u2010of\u2010bed mobilizations improve outcome. We hypothesized that utilization of a dual lumen cannula (DLC) for V\u2010V ECMO would facilitate out\u2010of\u2010bed mobilization compared to single lumen cannulas (SLC).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Retrospective single center registry study including all V\u2010V ECMO patients cannulated between 10\/2010 and 05\/2021 for respiratory failure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The registry included 355\u2009V\u2010V ECMO patients (median age 55.6\u2009years, 31.8% female, 27.3% with preexisting pulmonary disease), 289\/355 (81.4%) primary cannulated with DLC, and 66\/355 (18.6%) using SLC. Both groups had similar pre\u2010ECMO characteristics. The runtime of the first ECMO cannula was significantly longer in DLC compared to SLC (169 vs. 115\u2009h, <jats:italic>p<\/jats:italic>\u2009=\u20090.015). The frequency of prone positioning during V\u2010V ECMO was similar in both groups (38.4 vs. 34.8%, <jats:italic>p<\/jats:italic>\u2009=\u20090.673). There was no difference in in\u2010bed mobilization (41.2 vs. 36.4%, for DLC and SLC, respectively, <jats:italic>p<\/jats:italic>\u2009=\u20090.491). Patients with DLC were more often mobilized out\u2010of\u2010bed (25.6 vs. 12.1%, OR 2.495 [95% CI 1.150 to 5.268], for DLC and SLC, respectively, <jats:italic>p<\/jats:italic>\u2009=\u20090.023). Hospital survival was similar in both groups (46.4 vs. 39.4%, for DLC and SLC, respectively, <jats:italic>p<\/jats:italic>\u2009=\u20090.339).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Patients cannulated with a dual lumen cannula for V\u2010V ECMO support were significantly more often mobilized out\u2010of\u2010bed. Since mobilization is important in prolonged ICU courses typical for ECMO patients, this might be an important benefit. Other benefits of DLC were the longer runtime of the initial cannula set and fewer suction events.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aor.14604","type":"journal-article","created":{"date-parts":[[2023,6,26]],"date-time":"2023-06-26T16:08:32Z","timestamp":1687795712000},"page":"1654-1662","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Dual lumen cannulation and mobilization of patients with venovenous extracorporeal membrane oxygenation"],"prefix":"10.1111","volume":"47","author":[{"given":"Christian","family":"Noe","sequence":"first","affiliation":[{"name":"Interdisciplinary Medical Intensive Care Faculty of Medicine, University of Freiburg Medical Center, University of Freiburg  Freiburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7458-6521","authenticated-orcid":false,"given":"Felix A.","family":"Rottmann","sequence":"additional","affiliation":[{"name":"Department of Medicine IV \u2013 Nephrology and Primary Care Faculty of Medicine, University of Freiburg Medical Center, University of Freiburg  Freiburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xavier","family":"Bemtgen","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Angiology I Faculty of Medicine, University of Freiburg Medical Center, University of Freiburg  Freiburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4056-3652","authenticated-orcid":false,"given":"Alexander","family":"Supady","sequence":"additional","affiliation":[{"name":"Interdisciplinary Medical Intensive Care Faculty of Medicine, University of Freiburg Medical Center, University of Freiburg  Freiburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tobias","family":"Wengenmayer","sequence":"additional","affiliation":[{"name":"Interdisciplinary Medical Intensive Care Faculty of Medicine, University of Freiburg Medical Center, University of Freiburg  Freiburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9423-9682","authenticated-orcid":false,"given":"Dawid L.","family":"Staudacher","sequence":"additional","affiliation":[{"name":"Interdisciplinary Medical Intensive Care Faculty of Medicine, University of Freiburg Medical Center, University of Freiburg  Freiburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,7,7]]},"reference":[{"key":"e_1_2_10_2_1","volume-title":"Acute respiratory distress syndrome","author":"Diamond M","year":"2023"},{"key":"e_1_2_10_3_1","first-page":"2526","article-title":"Acute respiratory distress syndrome. 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