{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T13:42:39Z","timestamp":1783518159805,"version":"3.55.0"},"reference-count":19,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2024,1,17]],"date-time":"2024-01-17T00:00:00Z","timestamp":1705449600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Artificial Organs"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Although acute kidney injury (AKI) has been established as an independent risk factor for in\u2010hospital mortality for patients on veno\u2010arterial (V\u2010A) extracorporeal membranous oxygenation (ECMO), the impact of Kidney Disease Improving Global Outcomes (KDIGO) stages of AKI has yet to be elucidated as a risk factor.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We conducted a retrospective analysis of patient outcomes based on KDIGO stages of AKI at a single institution. The analysis was a cohort of 179 patients; 66 without AKI, 19 with stage 1 AKI, 18 with stage 2 AKI, and 76 with stage 3 AKI.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Every 1\u2010year increase in age was associated with 4% increased odds of mortality at 30\u2009days (95% confidence interval [CI] 1.01, 1.07; <jats:italic>p<\/jats:italic>\u2009=\u20090.004). The presence of AKI at any stage was associated with 59% increased odds of 30\u2010day mortality (95% CI 0.81, 3.10; <jats:italic>p<\/jats:italic>\u2009=\u20090.176). The presence of stage 1 AKI was associated with a 5% decreased odds of 30\u2010day mortality (95% CI 0.32, 2.89). The presence of stage 2 AKI (odds ratio [OR] 2.29, 95% CI 0.69, 7.55; <jats:italic>p<\/jats:italic>\u2009=\u20090.173) and stage 3 AKI (OR 1.68, 95% CI 0.81, 3.46; <jats:italic>p<\/jats:italic>\u2009=\u20090.164) was associated with increased odds of 30\u2010day mortality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Based on our single\u2010center study, higher KDIGO stages of AKI likely have increased odds of mortality at 30\u2009days. Larger studies are needed to confirm these findings.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aor.14714","type":"journal-article","created":{"date-parts":[[2024,1,18]],"date-time":"2024-01-18T07:15:22Z","timestamp":1705562122000},"page":"763-770","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["The impact of acute kidney injury stages on the outcomes of veno\u2010arterial extracorporeal membrane oxygenation"],"prefix":"10.1111","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3164-344X","authenticated-orcid":false,"given":"Akhil S.","family":"Kallur","sequence":"first","affiliation":[{"name":"Department of Internal Medicine MedStar Washington Hospital Center, Georgetown University  Washington DC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julian","family":"Armijo\u2010Alba","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine MedStar Washington Hospital Center, Georgetown University  Washington DC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5145-8386","authenticated-orcid":false,"given":"Jacqueline L.","family":"Russell","sequence":"additional","affiliation":[{"name":"Department of General Surgery MedStar Georgetown University Hospital  Washington DC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tariq","family":"Sallam","sequence":"additional","affiliation":[{"name":"Division of Pulmonary, Critical Care and Sleep Medicine Brown University  Providence Rhode Island USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fred","family":"Bien\u2010Aime","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine MedStar Washington Hospital Center, Georgetown University  Washington DC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kavya K.","family":"Sanghavi","sequence":"additional","affiliation":[{"name":"MedStar Health Research Institute  Hyattsville Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohil","family":"Garg","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine MedStar Washington Hospital Center, Georgetown University  Washington DC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naveera","family":"Khan","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine MedStar Washington Hospital Center, Georgetown University  Washington DC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0773-8764","authenticated-orcid":false,"given":"Mouaz\u00a0Haj","family":"Bakri","sequence":"additional","affiliation":[{"name":"Division of Hospital Medicine Shands Hospital, University of Florida  Gainesville Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louay","family":"Zaghlol","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine MedStar Washington Hospital Center, Georgetown University  Washington DC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Imran","family":"Khan","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine MedStar Washington Hospital Center, Georgetown University  Washington DC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shadi","family":"El\u2010Akawi","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine MedStar Washington Hospital Center, Georgetown University  Washington DC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adrian","family":"Llama","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine MedStar Washington Hospital Center, Georgetown University  Washington DC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yazan","family":"Sawalha","sequence":"additional","affiliation":[{"name":"Department of Medicine MedStar St. Mary's Hospital  Leonardtown Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suraj","family":"Trivedi","sequence":"additional","affiliation":[{"name":"Critical Care Medicine MedStar Washington Hospital Center, Georgetown University  Washington DC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aiman","family":"Alassar","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery MedStar Washington Hospital Center, Georgetown University  Washington DC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3147-5044","authenticated-orcid":false,"given":"Akram\u00a0M.","family":"Zaaqoq","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Division of Critical Care University of Virginia  Charlottesville Virginia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,1,17]]},"reference":[{"key":"e_1_2_10_2_1","volume-title":"Updates in anesthesia \u2013 the operating room and beyond","author":"Akram 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