{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T19:12:32Z","timestamp":1782846752741,"version":"3.54.5"},"reference-count":25,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,3,29]],"date-time":"2024-03-29T00:00:00Z","timestamp":1711670400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Artificial Organs"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>As the pandemic progressed, the use of extracorporeal membrane oxygenation (ECMO) for COVID\u201019\u2010related acute respiratory distress syndrome increased, and patient triage and transfer to ECMO centers became important to optimize patient outcomes. Our objectives are to identify predictors of patient transfer for veno\u2010venous extracorporeal membrane oxygenation (V\u2010V ECMO) evaluation as well as to describe the outcomes of accepted patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This is a single\u2010center, retrospective analysis of V\u2010V ECMO transfer requests for adult patients with known or suspected COVID\u201019 and respiratory failure from March 2020 until March 2021. Data were collected prospectively during the triage process for transfer requests as part of clinical patient care at our institution.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 341 referred patients, 112 (33%) were accepted for transfer to our facility, whereas 229 (67%) patients were declined for transfer. The Classification and Regression Tree analysis showed that patients' high pressure during airway pressure release ventilation (APRV) and age were the variables most significantly associated with the decision to accept or decline patients for transfer.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our triage process enabled one\u2010third of referred patients to be transferred for evaluation, with nearly 70% of those patients ultimately receiving ECMO support. High ventilator settings on APRV and young age were associated with acceptance for transfer. Accepted patients also had a higher incidence of adjunctive therapies (proning and paralysis) prior to transfer request, less cardiac or renal dysfunction, and a shorter duration of mechanical ventilation. Further research is warranted to investigate the outcomes of nontransferred patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aor.14723","type":"journal-article","created":{"date-parts":[[2024,3,29]],"date-time":"2024-03-29T13:03:09Z","timestamp":1711717389000},"page":"665-674","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Triage of V\u2010V ECMO referrals for COVID\u201019 respiratory failure"],"prefix":"10.1111","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5750-0004","authenticated-orcid":false,"given":"Erin","family":"Niles","sequence":"first","affiliation":[{"name":"Critical Care Resuscitation Unit, R Adams Cowley Shock Trauma Center  Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel J.","family":"Haase","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine University of Maryland School of Medicine  Baltimore Maryland USA"},{"name":"Department of Surgery University of Maryland School of Medicine  Baltimore Maryland USA"},{"name":"Program in Trauma, R Adams Cowley Shock Trauma Center University of Maryland School of Medicine  Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7774-154X","authenticated-orcid":false,"given":"Quincy","family":"Tran","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine University of Maryland School of Medicine  Baltimore Maryland USA"},{"name":"Program in Trauma, R Adams Cowley Shock Trauma Center University of Maryland School of Medicine  Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James A.","family":"Gerding","sequence":"additional","affiliation":[{"name":"Critical Care Resuscitation Unit, R Adams Cowley Shock Trauma Center  Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily","family":"Esposito","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine University of Maryland School of Medicine  Baltimore Maryland USA"},{"name":"Program in Trauma, R Adams Cowley Shock Trauma Center University of Maryland School of Medicine  Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siamak","family":"Dahi","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Cardiac Surgery University of Maryland School of Medicine  Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr","given":"Samuel M.","family":"Galvagno","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology University of Maryland School of Medicine  Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kimberly","family":"Boswell","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine University of Maryland School of Medicine  Baltimore Maryland USA"},{"name":"Program in Trauma, R Adams Cowley Shock Trauma Center University of Maryland School of Medicine  Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raymond","family":"Rector","sequence":"additional","affiliation":[{"name":"Perfusion Services University of Maryland Medical Center  Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Pearce","sequence":"additional","affiliation":[{"name":"University of Maryland Access Center  Linthicum Heights Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maie","family":"Abdel\u2010Wahab","sequence":"additional","affiliation":[{"name":"University of Maryland School of Medicine, 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USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth K.","family":"Powell","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine University of Maryland School of Medicine  Baltimore Maryland USA"},{"name":"Program in Trauma, R Adams Cowley Shock Trauma Center University of Maryland School of Medicine  Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,3,29]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13054\u2010020\u201003240\u20107"},{"key":"e_1_2_9_3_1","unstructured":"AnesiG.COVID\u201019: Epidemiology clinical features and prognosis of the critically ill adult. 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