{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:44:25Z","timestamp":1787013865280,"version":"build-2736575974"},"reference-count":25,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2024,6,2]],"date-time":"2024-06-02T00:00:00Z","timestamp":1717286400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Artificial Organs"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Hospital readmissions following left ventricular assist device (LVAD) remain a frequent comorbidity, associated with decreased quality of life and increased resources utilization. This study sought to determine causes, predictors, and impact on survival of hospitalizations during HeartMate 3 (HM3) support.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>All patients implanted with HM3 between November 2014 to December 2019 at Columbia University Irving Medical Center were consecutively enrolled in the study. Demographics and clinical characteristics from the index admission and the first outpatient visit were collected and used to estimate 1\u2010year and 900\u2010day readmission\u2010free survival and overall survival. Multivariable analysis was performed for subsequent readmissions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of 182 patients who received a HM3 LVAD, 167 (92%) were discharged after index admission and experienced 407 unplanned readmissions over the median follow up of 727 (interquartile range (IQR): 410.5, 1124.5) days. One\u2010year and 900\u2010day mean cumulative number of all\u2010cause unplanned readmissions was 0.43 (95%CI, 0.36, 0.51) and 1.13 (95%CI, 0.99, 1.29). The most frequent causes of rehospitalizations included major infections (29.3%), bleeding (13.2%), device\u2010related (12.5%), volume overload (7.1%), and other (28%). One\u2010year and 900\u2010day survival free from all\u2010cause readmission was 38% (95%CI, 31\u201346%) and 16.6% (95%CI, 10.3\u201324.4%). One\u2010year and 900\u2010day freedom from 2, 3, and\u2009\u22654 readmissions were 60.7%, 74%, 74.5% and 26.2%, 33.3%, 41.3%. One\u2010year and 900\u2010day survival were unaffected by the number of readmissions and remained &gt;90%. Male sex, ischemic etiology, diabetes, lower serum creatinine, longer duration of index hospitalization, and a history of readmission between discharge and the first outpatient visit were associated with subsequent readmissions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Unplanned hospital readmissions after HM3 are common, with infections and bleeding accounting for the majority of readmissions. Irrespective of the number of readmissions, one\u2010year survival remained unaffected.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/aor.14763","type":"journal-article","created":{"date-parts":[[2024,6,3]],"date-time":"2024-06-03T02:30:25Z","timestamp":1717381825000},"page":"1049-1059","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Unplanned hospital readmissions following\n                    <scp>HeartMate<\/scp>\n                    3 implantation: Readmission rates, causes, and impact on survival"],"prefix":"10.1111","volume":"48","author":[{"given":"Hueyjong","family":"Shih","sequence":"first","affiliation":[{"name":"Department of Surgery, Division of Cardiothoracic and Vascular Surgery Columbia University Medical Center  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giulio M.","family":"Mondellini","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine, Department of Cardiology, New York Presbyterian Hospital Columbia University  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul A.","family":"Kurlansky","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Cardiothoracic and Vascular Surgery Columbia University Medical Center  New York New York USA"},{"name":"Center for Innovation and Outcomes Research, Department of Surgery Columbia University  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jocelyn","family":"Sun","sequence":"additional","affiliation":[{"name":"Center for Innovation and Outcomes Research, Department of Surgery Columbia University  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuming","family":"Ning","sequence":"additional","affiliation":[{"name":"Center for Innovation and Outcomes Research, Department of Surgery Columbia University  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vivian R.","family":"Feldman","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine, Department of Cardiology, New York Presbyterian Hospital Columbia University  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melie","family":"Tiburcio","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine, Department of Cardiology, New York Presbyterian Hospital Columbia University  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Conor W.","family":"Maguire","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine, Department of Cardiology, New York Presbyterian Hospital Columbia University  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annamaria","family":"Ladanyi","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine, Department of Cardiology, New York Presbyterian Hospital Columbia University  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin","family":"Clerkin","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine, Department of Cardiology, New York Presbyterian Hospital Columbia University  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshifumi","family":"Naka","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Cardiothoracic and Vascular Surgery Columbia University Medical Center  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriel T.","family":"Sayer","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine, Department of Cardiology, New York Presbyterian Hospital Columbia University  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nir","family":"Uriel","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine, Department of Cardiology, New York Presbyterian Hospital Columbia University  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo C.","family":"Colombo","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine, Department of Cardiology, New York Presbyterian Hospital Columbia University  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koji","family":"Takeda","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Cardiothoracic and Vascular Surgery Columbia University Medical Center  New York New York 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