{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T07:12:39Z","timestamp":1779174759878,"version":"3.51.4"},"reference-count":22,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2024,9,30]],"date-time":"2024-09-30T00:00:00Z","timestamp":1727654400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Artificial Organs"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Ventricular tachycardia (VT) ablation is a high\u2010risk procedure, particularly due to the potential for hemodynamic instability. Mechanical circulatory support (MCS) is increasingly utilized to manage these risks. This study investigated the in\u2010hospital outcomes of VT ablation with MCS use, emphasizing its impact on mortality and procedural complications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrospectively analyzed patients undergoing VT ablation from 2019 to 2020, using the National Inpatient Sample data. Patients aged 18\u2009years and over were included. MCS includes a percutaneous left ventricular assist device (pLVAD), extracorporeal membrane oxygenation (ECMO), and intraaortic balloon pump (IABP). We also conducted a subgroup analysis for patients experiencing cardiogenic shock (CS). The primary outcome was in\u2010hospital mortality; secondary outcomes included acute kidney injury (AKI), AKI\u2010requiring dialysis, any bleeding events, gastrointestinal bleeding, ischemic stroke, heart transplant, and durable LVAD (dLVAD) utilization.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We included 14\u2009450 patients, of whom 6.5% utilized MCS. The MCS group showed a higher in\u2010hospital mortality rate than the non\u2010MCS group (24% vs. 2%, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.01). Secondary outcomes showed statistically higher rates in the MCS group compared to the non\u2010MCS groups. Stratification by MCS modality did not affect outcomes except that pLVAD was associated with lower rates of AKI. In the CS subgroup, the MCS group exhibited significantly higher mortality compared to the non\u2010MCS group (32% vs. 8.4%, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.01).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The use of MCS during VT ablation is associated with increased in\u2010hospital mortality, underscoring the severity of cases requiring such support. These findings show the need for careful assessment and optimal usage of MCS to enhance patient outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aor.14877","type":"journal-article","created":{"date-parts":[[2024,9,30]],"date-time":"2024-09-30T09:14:47Z","timestamp":1727687687000},"page":"681-690","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Impact of mechanical circulatory support on in\u2010hospital outcomes among patients with ventricular tachycardia requiring ablation"],"prefix":"10.1111","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9758-4177","authenticated-orcid":false,"given":"Kenji","family":"Hashimoto","sequence":"first","affiliation":[{"name":"Westmead Applied Research Centre University of Sydney  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdul Rahman","family":"Akkawi","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Kansas University School of Medicine\u2010Wichita  Wichita Kansas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamad","family":"Ghazal","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Albany Medical College  Albany New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5740-9670","authenticated-orcid":false,"given":"Alexandros","family":"Briasoulis","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Section of Heart Failure and Transplantation University of Iowa  Iowa City Iowa USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshiki","family":"Kuno","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine Montefiore Medical Center, Albert Einstein College of Medicine  Bronx New York USA"},{"name":"Cardiology Division Massachusetts General Hospital, Harvard Medical School  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