{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T11:13:40Z","timestamp":1791976420986,"version":"4.4.0"},"reference-count":19,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,10,9]],"date-time":"2024-10-09T00:00:00Z","timestamp":1728432000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Artificial Organs"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Durable biventricular support may be necessary to bridge patients with end\u2010stage biventricular failure to heart transplantation. This study compares waitlist and post\u2010transplant outcomes between patients supported with continuous flow, durable biventricular assist devices (BiVAD), and total artificial heart (TAH).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Using the UNOS registry, we analyzed adult (\u226518\u2009years old), first\u2010time transplant candidates with TAH or BiVAD at the time of listing or transplantation from 10\/1\/2010\u201310\/31\/2020, with follow\u2010up through 3\/31\/2022. Multivariable proportional subdistribution hazards models and cause\u2010specific Cox proportional hazards models were used to compare death\/deterioration or heart transplantation on the waitlist between cohorts. Kaplan\u2013Meier and multivariable Cox proportional hazards model were used to evaluate one\u2010year post\u2010transplant survival and evaluate difference in outcomes based on annual transplant center volume.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The waitlist cohort included a total of 228 patients (25% BiVAD). Waitlist outcomes between device types were similar. The transplanted cohort included a total of 352 patients (25% BiVAD). There was a trend towards worse one\u2010year post\u2010transplant survival in patients bridged with TAH versus BiVAD (log\u2010rank <jats:italic>p<\/jats:italic>\u2010value\u2009=\u20090.072) that persisted after adjusting for age, gender, policy, and removing dual\u2010organ recipients (HR 1.94 (0.94, 3.98) <jats:italic>p<\/jats:italic>\u2010value\u2009=\u20090.07). There was a difference in one\u2010year post\u2010transplant survival amongst TAH\u2010bridged patients when stratified by annual transplant center volume (log\u2010rank <jats:italic>p<\/jats:italic>\u2010value\u2009=\u20090.013). One\u2010year post\u2010transplant survival between TAH\u2010supported patients from high annual transplant volume centers and BiVAD\u2010supported patients was similar (<jats:italic>p<\/jats:italic>\u2010value\u2009=\u20090.815).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>BiVAD and TAH are reasonable support strategies with TAH implantation at high\u2010volume transplant centers (51+ transplants\/year) having similar 1\u2010year post\u2010transplant survival to BiVAD\u2010supported patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aor.14884","type":"journal-article","created":{"date-parts":[[2024,10,9]],"date-time":"2024-10-09T12:23:28Z","timestamp":1728476608000},"page":"281-291","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Comparison of waitlist and post\u2010transplant outcomes in patients supported with total artificial heart versus continuous biventricular assist devices"],"prefix":"10.1111","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8054-4096","authenticated-orcid":false,"given":"Joel","family":"Ferrall","sequence":"first","affiliation":[{"name":"Keck School of Medicine University of Southern California  Los Angeles California USA"},{"name":"Department of Anthropology University of Southern California  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ajay S.","family":"Vaidya","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine Keck School of Medicine of the University of Southern California  Los Angeles California USA"},{"name":"Department of Medicine Keck School of Medicine of the University of Southern California  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric S.","family":"Kawaguchi","sequence":"additional","affiliation":[{"name":"Department of Population and Public Health Sciences, Keck School of Medicine University of Southern California  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjeet G.","family":"Patel","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery Keck School of Medicine of the University of Southern California  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raymond C.","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery Keck School of Medicine of the University of Southern California  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily S.","family":"Lee","sequence":"additional","affiliation":[{"name":"Keck School of Medicine University of Southern California  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9695-185X","authenticated-orcid":false,"given":"Aaron M.","family":"Wolfson","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine Keck School of Medicine of the University of Southern California  Los Angeles California USA"},{"name":"Department of Medicine Keck School of Medicine of the University of Southern California  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,10,9]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2018.04.004"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2017.08.019"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2022.11.023"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2023.05.020"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocs.16329"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.21037\/acs.2020.03.07"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAT.0000000000001900"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocs.12823"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1214\/aos\/1176350951"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1080\/01621459.1999.10474144"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2011.02.086"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.15265"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2022.11.034"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2004.10.008"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2011.09.040"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAT.0000000000001966"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/CRD.0000000000000421"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1080\/03610926.2016.1277759"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/biomet\/81.1.61"}],"container-title":["Artificial Organs"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aor.14884","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,11]],"date-time":"2025-02-11T07:39:09Z","timestamp":1739259549000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/aor.14884"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,9]]},"references-count":19,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,2]]}},"alternative-id":["10.1111\/aor.14884"],"URL":"https:\/\/doi.org\/10.1111\/aor.14884","archive":["Portico"],"relation":{},"ISSN":["0160-564X","1525-1594"],"issn-type":[{"value":"0160-564X","type":"print"},{"value":"1525-1594","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10,9]]},"assertion":[{"value":"2024-06-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication 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