{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T14:01:08Z","timestamp":1780149668737,"version":"3.54.0"},"reference-count":32,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,2,5]],"date-time":"2025-02-05T00:00:00Z","timestamp":1738713600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,2,5]],"date-time":"2025-02-05T00:00:00Z","timestamp":1738713600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100010425","name":"Tri-Service General Hospital","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010425","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Artificial Organs"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>The mortality rate of acute myocardial infarction (AMI)\u2010related refractory cardiogenic shock (rCS) remains high, particularly in patients experiencing cardiac arrest with extracorporeal cardiopulmonary resuscitation (ECPR). This study aimed to evaluate the outcomes of early escalation to CentriMag for AMI\u2010induced out\u2010of\u2010hospital cardiac arrest (OHCA) with ECPR.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Patients with AMI\u2010induced OHCA with refractory to ECMO support after ECPR were enrolled. Clinical data were analyzed to identify predictive factors for mortality and survival benefits.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Eighty\u2010nine patients were enrolled, of whom 26 underwent CentriMag implantation. The 1\u2010year survival rate for those with the implantation was 34.6%. In contrast, those without implantation showed a survival rate of 7.9%. The average time from the initiation of ECPR to CentriMag implantation was 22.5\u2009\u00b1\u200914.6\u2009h. The surgical mortality group exhibited a larger body surface area, longer intervals from CPR to ECPR, shorter duration of CentriMag support, and higher preoperative serum creatinine and postoperative day 1 serum aspartate aminotransferase levels. A prolonged interval from CPR to ECPR was identified as an independent risk factor for mortality. Extended duration of CentriMag support was associated with improved survival outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Early CentriMag implantation rescues patients experiencing AMI\u2010related OHCA with rCS and refractory to ECMO support after ECPR. This intervention provides a critical time window, serving as a safe bridge to decision.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/aor.14957","type":"journal-article","created":{"date-parts":[[2025,2,5]],"date-time":"2025-02-05T03:48:46Z","timestamp":1738727326000},"page":"1021-1029","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Early Escalation to\n                    <scp>CentriMag<\/scp>\n                    for Acute Myocardial Infarction\u2010Induced Out\u2010of\u2010Hospital Cardiac Arrest With Refractory to Extracorporeal Membrane Oxygen Support"],"prefix":"10.1111","volume":"49","author":[{"given":"Yi\u2010Han","family":"Jhuang","sequence":"first","affiliation":[{"name":"Division of Cardiovascular Surgery, Department of Surgery Tri\u2010Service General Hospital, National Defense Medical Center  Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi\u2010Ting","family":"Tsai","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Surgery, Department of Surgery Tri\u2010Service General Hospital, National Defense Medical Center  Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chih\u2010Yuan","family":"Lin","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Surgery, Department of Surgery Tri\u2010Service General Hospital, National Defense Medical Center  Taipei Taiwan"},{"name":"Department of Biochemistry National Defense Medical Center  Taipei Taiwan"},{"name":"Institute of Preventive Medicine National Defense Medical Center  Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-7992-4771","authenticated-orcid":false,"given":"Hung\u2010Yen","family":"Ke","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular 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National Defense Medical Center  Taipei Taiwan"},{"name":"Department of Biochemistry National Defense Medical Center  Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chien\u2010Sung","family":"Tsai","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Surgery, Department of Surgery Tri\u2010Service General Hospital, National Defense Medical Center  Taipei Taiwan"},{"name":"Department and Graduate Institute of Pharmacology National Defense Medical Center  Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,2,5]]},"reference":[{"issue":"16","key":"e_1_2_9_2_1","first-page":"e232","article-title":"Contemporary Management of Cardiogenic Shock: A Scientific Statement From the American Heart Association","volume":"136","author":"Diepen 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