{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T16:08:59Z","timestamp":1772986139996,"version":"3.50.1"},"reference-count":29,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T00:00:00Z","timestamp":1759536000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T00:00:00Z","timestamp":1759536000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Artificial Organs"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>A substantial proportion of patients receiving left ventricular assist devices (LVADs) present with pre\u2010existing atrial fibrillation (AF). However, the prognostic significance of AF\u2014particularly regarding overall survival and ventricular arrhythmias (VAs)\u2014remains unclear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Patients included were those from the multicenter ASSIST\u2010ICD observational study. The association between AF and the primary endpoint of all\u2010cause mortality was evaluated using a 1:1 propensity score\u2010matched cohort. Secondary outcomes included cardiovascular and non\u2010cardiac mortality, bleeding, stroke, pump thrombosis, and the occurrence of early (\u2264\u200930\u2009days post\u2010implant) and late VAs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 652 LVAD recipients, 286 patients (43.9%) had a history of AF before LVAD implantation, with a median follow\u2010up of 9.1\u2009months (2.5\u201322.1). AF patients were older, with higher rates of dilated cardiomyopathy, a history of VAs, and longer heart failure duration. After matching, AF was not associated with higher mortality (HR 0.93 [0.69\u20131.26]). AF subtype (paroxysmal, persistent, permanent) had no impact on mortality. There were no significant differences in cardiovascular\/non\u2010cardiac mortality, bleeding, ischemic stroke, pump thrombosis, or early VAs. However, AF was linked to a higher incidence of late VAs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In this large multicenter study, AF before LVAD implantation was not associated with increased risks of mortality, bleeding, stroke, or pump thrombosis, but was linked to a higher incidence of late VAs. These findings, based on earlier\u2010generation devices, should be interpreted cautiously given the recent adoption of the HeartMate 3, offering improved hemocompatibility. Further studies are needed to identify LVAD patients where AF carries clinical significance and guide optimal management.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/aor.70020","type":"journal-article","created":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T07:25:35Z","timestamp":1759562735000},"page":"119-128","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Preoperative Atrial Fibrillation Does Not Impact Long\u2010Term Survival and Complications in Left Ventricular Assistance Device Recipients"],"prefix":"10.1111","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-8952-6283","authenticated-orcid":false,"given":"Miloud","family":"Cherbi","sequence":"first","affiliation":[{"name":"Cardiology Department Toulouse University Hospital  Toulouse 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Rennes, CHU Rennes CIC 1414, INSERM, LTSI \u2010 UMR 1099  Rennes France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,10,4]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2022.12.004"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2006.01.060"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(98)00297-6"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2014.07.989"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAT.0000000000000520"},{"issue":"6","key":"e_1_2_11_7_1","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.116.005340","article-title":"Atrial Arrhythmias and Electroanatomical Remodeling in Patients With Left Ventricular Assist Devices","volume":"8","author":"Deshmukh A.","year":"2017","journal-title":"Journal of the American Heart 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