{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T19:25:58Z","timestamp":1791314758827,"version":"4.3.1"},"reference-count":42,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T00:00:00Z","timestamp":1759881600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T00:00:00Z","timestamp":1759881600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Artificial Organs"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>In recent decades, temporary mechanical circulatory support (tMCS) devices have garnered increasing interest for the treatment of cardiogenic shock. PulseCath\u2014a pulsatile ventricular assist device\u2014may address a critical unmet need within the tMCS array, offering an intermediate level of support between that of intra\u2010aortic balloon pump (IABP) and more invasive tMCS devices (e.g., Impella and ECMO).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a systematic search of PubMed\/MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, Web of Science, Scopus, and Google Scholar databases to retrieve available clinical and preclinical in\u00a0vivo data regarding the implantation of PulseCath.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Five preclinical in\u00a0vivo studies (38 animal models) and 16 clinical studies (386 patients) were identified and retrieved. When implanted in humans, PulseCath was mostly employed with a \u201cpre\u2010emptive\u201d strategy, particularly in the context of high\u2010risk percutaneous coronary interventions. However, cases reporting its \u201cbail\u2010out\u201d deployment in instances of hemodynamic instability were also identified.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>While the underreporting of adverse events and of PulseCath use as a bailout strategy across literature constrains a definitive evaluation of the device, preliminary findings suggest an apparent ease of use. Therefore, further research is warranted to better delineate which specific patient population would most likely benefit from the implantation of such a device. As such, the integration of underlying pathophysiological data, individualized risk assessment, and more robust clinical studies may potentially expand its use.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/aor.70022","type":"journal-article","created":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T09:45:54Z","timestamp":1759916754000},"page":"355-370","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Clinical and Preclinical Evidence on a Novel Percutaneous Pulsatile Ventricular Assist Device (\n                    <scp>PulseCath<\/scp>\n                    ): A Scoping Review"],"prefix":"10.1111","volume":"50","author":[{"given":"Viviana Teresa","family":"Agosta","sequence":"first","affiliation":[{"name":"Department of Anesthesia and Intensive Care IRCCS San Raffaele Scientific Institute  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6313-9160","authenticated-orcid":false,"given":"Jacopo","family":"D\u2019Andria Ursoleo","sequence":"additional","affiliation":[{"name":"Department of Anesthesia and Intensive Care IRCCS San Raffaele Scientific Institute  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Corrado","family":"D\u2019Andria","sequence":"additional","affiliation":[{"name":"Allergy and Immunopathology Unit, Department of Internal Medicine SS. Annunziata General Hospital  Taranto Italy"},{"name":"Department of Translational Medicine and Neurosciences, School of Medicine and Surgery Aldo Moro University of Bari  Bari Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-2428-5394","authenticated-orcid":false,"given":"Alice","family":"Bottussi","sequence":"additional","affiliation":[{"name":"Department of Anesthesia and Intensive Care IRCCS San Raffaele Scientific Institute  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5186-1976","authenticated-orcid":false,"given":"Fabrizio","family":"Monaco","sequence":"additional","affiliation":[{"name":"Department of Anesthesia and Intensive Care IRCCS San Raffaele Scientific Institute  Milan 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