{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T07:20:00Z","timestamp":1789888800281,"version":"4.0.1"},"reference-count":31,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T00:00:00Z","timestamp":1763683200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T00:00:00Z","timestamp":1763683200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Artificial Organs"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Cannulation for peripheral veno\u2010arterial extracorporeal membrane oxygenation (V\u2010A ECMO) can lead to severe local complications. This study evaluated site\u2010specific complications between percutaneous and surgical cannulation techniques for femoro\u2010femoral V\u2010A ECMO, focusing on site bleeding, infection, and limb ischemia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a single\u2010center retrospective cohort study of adult patients who received femoro\u2010femoral V\u2010A ECMO either by percutaneous or surgical technique at a tertiary center. Cannulation\u2010site complications were assessed from cannulation to post\u2010decannulation. Risk factors for site bleeding, infection, and limb ischemia within 90\u2009days of cannulation were analyzed using logistic regression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among 384 patients (22.4% female), 181 (47.1%) underwent percutaneous, and 203 (52.9%) underwent surgical cannulation. Percutaneous cannulation was associated with significantly fewer patients experiencing site bleeding (29.3% vs. 40.9%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.02) and infection (8.3% vs. 31.0%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), with no significant difference in limb ischemia (11.6% vs. 15.3%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.29). 90\u2010day survival was similar between groups (43.6% vs. 49.8%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.81). Multivariable logistic regression identified surgical cannulation as an independent risk factor for site bleeding (OR 2.39, 95% CI 1.43\u20133.98;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and infection (OR 5.47; 95% CI 2.47\u201312.12;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Limb ischemia was not significantly associated with the cannulation technique but with two other modifiable factors at cannulation: absence of distal perfusion catheterization and larger arterial cannula size.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Percutaneous cannulation was associated with significantly fewer patients experiencing site bleeding and infection compared to surgical cannulation. Limb ischemia was not associated with the cannulation technique but was influenced by two other modifiable factors at cannulation: distal perfusion catheterization and arterial cannula size.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/aor.70061","type":"journal-article","created":{"date-parts":[[2025,11,22]],"date-time":"2025-11-22T02:59:20Z","timestamp":1763780360000},"page":"440-448","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Percutaneous Versus Surgical Cannulation for Femoro\u2010Femoral Venoarterial Extracorporeal Membrane Oxygenation: A Retrospective Cohort Study on Cannulation\u2010Related Complications"],"prefix":"10.1111","volume":"50","author":[{"given":"Axel","family":"Dimberg","sequence":"first","affiliation":[{"name":"Department of Molecular Medicine and Surgery Karolinska Institutet  Stockholm Sweden"},{"name":"Department of Cardiothoracic Surgery Karolinska University Hospital  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magnus","family":"Dal\u00e9n","sequence":"additional","affiliation":[{"name":"Department of Molecular Medicine and Surgery Karolinska Institutet  Stockholm Sweden"},{"name":"Department of Cardiothoracic Surgery Karolinska University Hospital  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anders","family":"Franco\u2010Cereceda","sequence":"additional","affiliation":[{"name":"Department of Molecular Medicine and Surgery Karolinska Institutet  Stockholm Sweden"},{"name":"Department of Cardiothoracic Surgery Karolinska University Hospital  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Fux","sequence":"additional","affiliation":[{"name":"Department of Physiology and Pharmacology Karolinska Institutet  Stockholm Sweden"},{"name":"Department of Perioperative Medicine and Intensive Care Karolinska University Hospital  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,11,21]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2018.11.038"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-018-5064-5"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12893-025-02835-7"},{"key":"e_1_2_13_5_1","first-page":"456","article-title":"Outcomes of Extracorporeal Membrane Oxygenation Support for Complex High\u2010Risk Elective Percutaneous Coronary Interventions: A Single\u2010Center Experience and Review of the Literature","volume":"30","author":"Shaukat A.","year":"2018","journal-title":"Journal of Invasive 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