{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T10:48:14Z","timestamp":1777632494680,"version":"3.51.4"},"reference-count":17,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T00:00:00Z","timestamp":1768780800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T00:00:00Z","timestamp":1768780800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Artificial Organs"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Backround<\/jats:title>\n                    <jats:p>The membrane oxygenator is a critical component of extracorporeal circulation (ECC), whose performance directly depends on its structural architecture. Differences in fiber geometry and winding patterns lead to variable hemodynamic pressure conditions. The resulting pressure drop Delta p (\u0394p) across the oxygenator module is a decisive indicator for system load and the risk of blood trauma. The aim of this study is the comparative analysis of the \u0394p of three commercial oxygenators: Medtronic Affinity Fusion, Eurosets A.L. ONE Plus, and LivaNova Inspire 8F, calculated from the difference between inlet and outlet pressure.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This prospective observational study included 60 patients divided into three groups of 20 patients each, based on the type of oxygenator used in their perfusion circuit.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The results of the study show that the \u0394p value was significantly higher for the Inspire 8F compared to the Affinity Fusion and A.L. ONE Plus oxygenators. Between measurement points T2 and T11, the highest \u0394p was 116\u2009\u00b1\u200956\u2009mmHg for the Medtronic group, 123\u2009\u00b1\u200926\u2009mmHg for the Eurosets group, and 168\u2009\u00b1\u200933\u2009mmHg for the Inspire 8F group. No significant differences in \u0394p were observed between the Affinity Fusion and the A.L. ONE Plus at any measurement point.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The results of the study show that the Inspire has the highest \u0394p of all the oxygenators examined in this study. In addition to potential influencing factors, the value is also dependent on the internal structure and the surface properties of the oxygenators. However, the present study does not help to clarify the effects of the pressure before and after the oxygenator or the \u0394p itself on hemolysis and subsequent clinical parameters associated with the use of different commercially available oxygenators.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/aor.70088","type":"journal-article","created":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T11:21:34Z","timestamp":1768821694000},"page":"564-571","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Comparative Analysis of Pressure Drop (\u0394p): Hemodynamic Performance of Three Commercial Oxygenators During Cardiopulmonary Bypass"],"prefix":"10.1111","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1452-625X","authenticated-orcid":false,"given":"Jan","family":"Turra","sequence":"first","affiliation":[{"name":"Department of Perfusiologie, Cardiac Surgery University Hospital Heidelberg  Heidelberg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martina","family":"Habermehl","sequence":"additional","affiliation":[{"name":"Department of Perfusiologie, Cardia Surgery University Hospital German Heart Centre Munich  Munich Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Schiepp","sequence":"additional","affiliation":[{"name":"Hochschule Furtwangen  Villingen\u2010Schwenningen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Rose","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery University Hospital Heidelberg  Heidelberg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Berthold","family":"Klein","sequence":"additional","affiliation":[{"name":"Department of Perfusiologie, Cardiac Surgery University Hospital Heidelberg  Heidelberg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benjamin","family":"Scheerer","sequence":"additional","affiliation":[{"name":"Department of Perfusiologie, Cardiac Surgery University Hospital Heidelberg  Heidelberg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthias","family":"Karck","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery University Hospital Heidelberg  Heidelberg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christoph","family":"Lichtenstern","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology University Hospital Heidelberg  Heidelberg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Riesterer David","family":"Max","sequence":"additional","affiliation":[{"name":"Department of Perfusiologie, Cardiac Surgery University Hospital Heidelberg  Heidelberg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dania","family":"Fischer","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology University Hospital Heidelberg  Heidelberg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,1,19]]},"reference":[{"key":"e_1_2_11_2_1","first-page":"305","volume-title":"Cardiopulmonary Bypass. Critical Care Obstetrics, Seventh Edition","author":"Sreshta E. G.","year":"2024"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v12.i41.6722"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13019-023-02406-y"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.141341"},{"issue":"1","key":"e_1_2_11_6_1","first-page":"15","article-title":"Clinical Evaluation of Contemporary Oxygenators","volume":"31","author":"Stanzel R. D. P.","year":"2016","journal-title":"Perfusion (United Kingdom)"},{"key":"e_1_2_11_7_1","volume-title":"A Clinical Evaluation of Contemporary Oxygenators: A Multi Centre Evaluation","author":"Stanzel R.","year":"2017"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1051\/ject\/201749160"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2003-43300"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/026765910101600203"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1177\/0267659113483803"},{"key":"e_1_2_11_12_1","article-title":"Beeinflusst Die Extrakorporale Zirkulation W\u00e4hrend Koronarer Bypassoperationen Das Ausma\u00df Und Die H\u00e4ufigkeit Der H\u00e4molyse?","volume":"31","author":"Micka N.","year":"2022","journal-title":"Kardiotechnik"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1191\/0267659103pf635oa"},{"key":"e_1_2_11_14_1","first-page":"9","article-title":"Oxygenator\u2010Leistungsvergleich: Compactflo Evolution Phisio M Versus Inspire 6 M Phisio","volume":"01","author":"M. Scheer M.","year":"2013","journal-title":"Kardiotechnik"},{"issue":"4","key":"e_1_2_11_15_1","first-page":"415","article-title":"Characterization of Shear Stress Mediated Platelet Dysfunction: Data From an Ex\u00a0Vivo Model for Extracorporeal Circulation and a Prospective Clinical Study","volume":"123","author":"Hidiatov O.","year":"2021","journal-title":"Thrombosis and Haemostasis"},{"issue":"1","key":"e_1_2_11_16_1","first-page":"156","article-title":"Risk Factors and Treatment of Oxygenator High\u2010Pressure Excursions During Cardiopulmonary Bypass","volume":"38","author":"Hj\u00e4rpe A. K.","year":"2023","journal-title":"Perfusion (United Kingdom)"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1051\/ject\/2025039"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1051\/ject\/2024019"}],"container-title":["Artificial Organs"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aor.70088","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/aor.70088","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aor.70088","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T04:07:06Z","timestamp":1777435626000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/aor.70088"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,19]]},"references-count":17,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["10.1111\/aor.70088"],"URL":"https:\/\/doi.org\/10.1111\/aor.70088","archive":["Portico"],"relation":{},"ISSN":["0160-564X","1525-1594"],"issn-type":[{"value":"0160-564X","type":"print"},{"value":"1525-1594","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,19]]},"assertion":[{"value":"2025-07-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-12-22","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-19","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}