{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,9]],"date-time":"2026-08-09T05:41:34Z","timestamp":1786254094015,"version":"build-2736575974"},"reference-count":13,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,4,26]],"date-time":"2026-04-26T00:00:00Z","timestamp":1777161600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,4,26]],"date-time":"2026-04-26T00:00:00Z","timestamp":1777161600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Artificial Organs"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Surgically implanted microaxial flow pumps (mAFP) are increasingly used for cardiogenic shock treatment. Standard mAFP explantation is performed bedside with a shortening of the vascular prosthesis, which may represent a potential source of infection in future. We analyzed the impact of gentamicin\u2010impregnated collagen sponge (GICS) application in the wound during mAFP explantation on the incidence of prosthetic graft infections.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Between 01\/2020 and 07\/2024, 235 patients underwent bedside full\u2010support mAFP explantation at our institution. Since 11\/2022, GICS has been routinely applied in 115 patients, while 120 previously were treated without it.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In the GICS\u2010group, after a median follow\u2010up of 221 [24; 351] days, 17 (14.8%) patients developed graft infection, resulting in 0.23 events per patient year (EPPY); surgery was necessary in 16 patients (13.9%). In the control group, after a median follow\u2010up of 399 [113; 654] days, infection occurred in 14 (11.7%) cases, 0.10 EPPY; surgical removal of the graft was necessary in 12 (10%). The GICS\u2010groups presented an increased risk for graft infections: sHR 2.49 [1.11; 5.59],\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.027. After propensity score matching for relevant demographic parameters, there was no significant difference in the risk reduction of total graft infections sHR 1.92 [0.79; 4,72],\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.15.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Local application of GICS did not reduce the risk of access site infections in patients undergoing bedside explantation of mAFP from the graft surgically anastomosed to an axillary artery.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/aor.70141","type":"journal-article","created":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T06:50:18Z","timestamp":1777272618000},"page":"1153-1163","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Impact of Gentamicin\u2010Impregnated Collagen Sponge on the Incidence of Access Related Infections After Full\u2010Support Microaxial Flow Pump Therapy"],"prefix":"10.1111","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9524-7705","authenticated-orcid":false,"given":"Gaik","family":"Nersesian","sequence":"first","affiliation":[{"name":"Department of Cardiothoracic and Vascular Surgery Deutsches Herzzentrum der Charit\u00e9 (DHZC)  Berlin Germany"},{"name":"DZHK (German Centre for Cardiovascular Research), partner Site Berlin  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maximilian","family":"Rauch","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic and Vascular Surgery Deutsches Herzzentrum der Charit\u00e9 (DHZC)  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9831-6289","authenticated-orcid":false,"given":"Daniel","family":"Lewin","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic and Vascular Surgery Deutsches Herzzentrum der Charit\u00e9 (DHZC)  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonard","family":"Pitts","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic and Vascular Surgery Deutsches Herzzentrum der Charit\u00e9 (DHZC)  Berlin Germany"},{"name":"DZHK (German Centre for Cardiovascular Research), partner Site Berlin  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julius","family":"Kaemmel","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic and Vascular Surgery Deutsches Herzzentrum der Charit\u00e9 (DHZC)  Berlin Germany"},{"name":"DZHK (German Centre for Cardiovascular Research), partner Site Berlin  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Stegmann","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic and Vascular Surgery Deutsches Herzzentrum der Charit\u00e9 (DHZC)  Berlin Germany"},{"name":"DZHK (German Centre for Cardiovascular Research), partner Site Berlin  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9089-8111","authenticated-orcid":false,"given":"Julia","family":"Stein","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic and Vascular Surgery Deutsches Herzzentrum der Charit\u00e9 (DHZC)  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuriy","family":"Hrytsyna","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic and Vascular Surgery Deutsches Herzzentrum der Charit\u00e9 (DHZC)  Berlin Germany"},{"name":"DZHK (German Centre for Cardiovascular Research), partner Site Berlin  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felix","family":"Schoenrath","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic and Vascular Surgery Deutsches Herzzentrum der Charit\u00e9 (DHZC)  Berlin Germany"},{"name":"DZHK (German Centre for Cardiovascular Research), partner Site Berlin  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Volkmar","family":"Falk","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic and Vascular Surgery Deutsches Herzzentrum der Charit\u00e9 (DHZC)  Berlin Germany"},{"name":"DZHK (German Centre for Cardiovascular Research), partner Site Berlin  Berlin Germany"},{"name":"Berlin Institute of Health at Charit\u00e9 \u2010 Universit\u00e4tsmedizin Berlin  Berlin Germany"},{"name":"Department of Health Sciences and Technology Institute of Translational Medicine, Translational Cardiovascular Technologies, Swiss Federal Institute of Technology (ETH) Zurich  Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evgenij","family":"Potapov","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic and Vascular Surgery Deutsches Herzzentrum der Charit\u00e9 (DHZC)  Berlin Germany"},{"name":"DZHK (German Centre for Cardiovascular Research), partner Site Berlin  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pia","family":"Lanmueller","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic and Vascular Surgery Deutsches Herzzentrum der Charit\u00e9 (DHZC)  Berlin Germany"},{"name":"DZHK (German Centre for Cardiovascular Research), partner Site Berlin  Berlin 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Organs"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aor.70141","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/aor.70141","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aor.70141","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,9]],"date-time":"2026-08-09T04:43:02Z","timestamp":1786250582000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/aor.70141"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,26]]},"references-count":13,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["10.1111\/aor.70141"],"URL":"https:\/\/doi.org\/10.1111\/aor.70141","archive":["Portico"],"relation":{},"ISSN":["0160-564X","1525-1594"],"issn-type":[{"value":"0160-564X","type":"print"},{"value":"1525-1594","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,26]]},"assertion":[{"value":"2026-01-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication 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