{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T09:05:49Z","timestamp":1784883949145,"version":"3.55.0"},"reference-count":5,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,6,7]],"date-time":"2026-06-07T00:00:00Z","timestamp":1780790400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,6,7]],"date-time":"2026-06-07T00:00:00Z","timestamp":1780790400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Artificial Organs"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>De novo aortic insufficiency (AI) is a recognized complication in patients supported with continuous\u2010flow durable left ventricular assist devices (LVADs), carrying important clinical consequences including heart failure progression and increased device\u2010related morbidity. We report the case of a HeartMate 3 (Abbott Inc., Chicago, Illinois, USA) patient, previously supported with a micro\u2010axial flow pump (mAFP), who developed severe AI within the first year of LVAD support and ultimately underwent urgent heart transplantation. Intraoperative inspection and histopathological analysis revealed mechanical injury of the aortic valve, likely initiated during mAFP implantation and subsequently exacerbated by LVAD\u2010related turbulent flow. These findings suggest that even subtle valve trauma may evolve into clinically significant AI under continuous\u2010flow support. This case underscores the need for a proactive strategy to minimize the risk of aortic valve micro\u2010lesions during mAFP placement, including meticulous preprocedural assessment of aortic root and valve anatomy and careful intraprocedural technique.<\/jats:p>","DOI":"10.1111\/aor.70159","type":"journal-article","created":{"date-parts":[[2026,6,7]],"date-time":"2026-06-07T16:20:44Z","timestamp":1780849244000},"page":"1087-1090","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Vanishing Aortic Valve Cusp: A Rare Case of Aortic Valve Insufficiency in a Durable Left Ventricular Assist Device Recipient After Micro\u2010Axial Flow Pump Support"],"prefix":"10.1111","volume":"50","author":[{"given":"Antonio","family":"Spitaleri","sequence":"first","affiliation":[{"name":"City of Health and Science University Hospital, Division of Cardiac Surgery, Department of Surgical Sciences University of Turin  Turin Italy"},{"name":"PhD Program in Bioengineering and Medical\u2010Surgical Sciences University of Turin, Politecnico di Torino  Turin Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guglielmo","family":"Gallone","sequence":"additional","affiliation":[{"name":"City of Health and Science University Hospital, Division of Cardiology, Department of Medical Sciences University of Turin  Turin Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Parrella","sequence":"additional","affiliation":[{"name":"City of Health and Science University Hospital, Division of Cardiac Surgery, Department of Surgical Sciences University of Turin  Turin Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Monteleone","sequence":"additional","affiliation":[{"name":"City of Health and Science University Hospital, Division of Cardiac Surgery, Department of Surgical Sciences University of Turin  Turin Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1977-7410","authenticated-orcid":false,"given":"Paola","family":"Cassoni","sequence":"additional","affiliation":[{"name":"City of Health and Science University Hospital, Unit of Pathology, Department of Medical Sciences University of Turin  Turin Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mauro","family":"Rinaldi","sequence":"additional","affiliation":[{"name":"City of Health and Science University Hospital, Division of Cardiac Surgery, Department of Surgical Sciences University of Turin  Turin Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Loforte","sequence":"additional","affiliation":[{"name":"City of Health and Science University Hospital, Division of Cardiac Surgery, Department of Surgical Sciences University of Turin  Turin Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,7]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchf.2018.07.012"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/aor.13825"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardfail.2019.08.003"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2014.06.057"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCHEARTFAILURE.120.007571"}],"container-title":["Artificial Organs"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aor.70159","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/aor.70159","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aor.70159","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T08:43:45Z","timestamp":1784882625000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/aor.70159"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,7]]},"references-count":5,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["10.1111\/aor.70159"],"URL":"https:\/\/doi.org\/10.1111\/aor.70159","archive":["Portico"],"relation":{},"ISSN":["0160-564X","1525-1594"],"issn-type":[{"value":"0160-564X","type":"print"},{"value":"1525-1594","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,7]]},"assertion":[{"value":"2025-11-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication 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