{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T15:02:28Z","timestamp":1790694148632,"version":"4.1.0"},"reference-count":10,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T00:00:00Z","timestamp":1778716800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T00:00:00Z","timestamp":1778716800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["23K11892"],"award-info":[{"award-number":["23K11892"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Artificial Organs"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Visual assessment of membrane motion is essential for managing EXCOR VAD, but accuracy depends on observer experience. We evaluated a high\u2010speed image AI model to support healthcare providers.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Patients on EXCOR Pediatric admitted to the University of Tokyo Hospital (May 2022\u2013May 2024) were included. Membrane images were obtained from patients and a manually filled pump at bench. An image recognition model was trained to estimate membrane position. Experienced physicians (\n                      <jats:italic>N<\/jats:italic>\n                      \u2009=\u200911) and inexperienced physicians (\n                      <jats:italic>N<\/jats:italic>\n                      \u2009=\u200911) assessed pump status in a sample dataset (\n                      <jats:italic>N<\/jats:italic>\n                      \u2009=\u200912) with and without AI assistance.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 142 movies from five patients were collected (98 training, 45 validation), plus 1100 bench images for training. Model accuracy was 0.91, with AUROCs of 0.99 (\u201cfill\u201d) and 0.96 (\u201cempty\u201d). Among experienced physicians, accuracy significantly improved with AI assistance from 0.83 (0.67\u20130.88) to 0.92 (0.92\u20131.0) (median (IQR);\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.016). Among inexperienced physicians, accuracy also significantly improved with AI assistance from 0.67 (0.5\u20130.75) to 0.83 (0.75\u20130.92) (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.049).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>A high\u2010speed image AI can facilitate the visual assessment of EXCOR VAD by healthcare providers.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/aor.70167","type":"journal-article","created":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T05:36:08Z","timestamp":1778823368000},"page":"1434-1442","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A High\u2010Speed Image\n                    <scp>AI<\/scp>\n                    Facilitating the Visual Assessment of the Membrane's Motion in\n                    <scp>EXCOR VAD<\/scp>"],"prefix":"10.1111","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9657-1646","authenticated-orcid":false,"given":"Hidehito","family":"Ota","sequence":"first","affiliation":[{"name":"Department of Pediatrics The University of Tokyo Hospital  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3859-2756","authenticated-orcid":false,"given":"Takuya","family":"Kawahara","sequence":"additional","affiliation":[{"name":"Clinical Research Promotion Center The University of Tokyo Hospital  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miki","family":"Ohta","sequence":"additional","affiliation":[{"name":"Clinical Research Promotion Center The University of Tokyo Hospital  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoshi","family":"Kodera","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine The University of Tokyo Hospital  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hironori","family":"Ebishima","sequence":"additional","affiliation":[{"name":"Department of Pediatrics The University of Tokyo Hospital  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9325-1877","authenticated-orcid":false,"given":"Fumiaki","family":"Shikata","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery The University of Tokyo Hospital  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7501-689X","authenticated-orcid":false,"given":"Ryo","family":"Inuzuka","sequence":"additional","affiliation":[{"name":"Department of Pediatrics The University of Tokyo Hospital  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1673-6891","authenticated-orcid":false,"given":"Yasutaka","family":"Hirata","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery National Center for Child Health and Development  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hikoro","family":"Matsui","sequence":"additional","affiliation":[{"name":"Department of Pediatrics The University of Tokyo Hospital  Tokyo Japan"},{"name":"Department of Pediatric Cardiology Sakakibara Heart Institute  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,14]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.112.000685"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(98)00914-X"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2007.11.567"},{"key":"e_1_2_11_5_1","unstructured":"BerlinHeart \u201cMedical Professionals EXCOR Pediatric \u201dhttps:\/\/www.berlinheart.de\/en\/medical\u2010professionals\/excorr\u2010pediatric\/."},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-021-01614-0"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/aor.14828"},{"key":"e_1_2_11_8_1","doi-asserted-by":"crossref","unstructured":"A.Howard M.Sandler G.Chu et\u00a0al. \u201cSearching for MobileNetV3 \u201d2019:arXiv:1905.02244.","DOI":"10.1109\/ICCV.2019.00140"},{"key":"e_1_2_11_9_1","doi-asserted-by":"crossref","unstructured":"R. R.Selvaraju M.Cogswell A.Das R.Vedantam D.Parikh andD.Batra \u201cGrad\u2010CAM: Visual Explanations From Deep Networks via Gradient\u2010Based Localization \u201d2016:arXiv:1610.02391.","DOI":"10.1109\/ICCV.2017.74"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.3758\/s13414-013-0605-z"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2024.08.005"}],"container-title":["Artificial Organs"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aor.70167","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/aor.70167","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aor.70167","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T14:47:32Z","timestamp":1790693252000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/aor.70167"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,14]]},"references-count":10,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2026,10]]}},"alternative-id":["10.1111\/aor.70167"],"URL":"https:\/\/doi.org\/10.1111\/aor.70167","archive":["Portico"],"relation":{},"ISSN":["0160-564X","1525-1594"],"issn-type":[{"value":"0160-564X","type":"print"},{"value":"1525-1594","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,14]]},"assertion":[{"value":"2025-10-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-06","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-14","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}