{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T08:30:58Z","timestamp":1793349058926,"version":"4.5.0"},"reference-count":27,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T00:00:00Z","timestamp":1786579200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T00:00:00Z","timestamp":1786579200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Artificial Organs"],"published-print":{"date-parts":[[2026,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Geometry of LVAD implantation is a determinant of pump performance and hemocompatibility. Despite technically successful operations, avoidable geometric errors may produce characteristic imaging patterns and clinically relevant device dysfunction.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To determine the frequency, diagnostic pathway, and clinical impact of preventable geometry\u2010related failure modes after HeartMate 3 implantation in a single\u2010center referral cohort, specifically inflow cannula malposition, outflow graft kinking\/excessive length, and aortic anastomotic stenosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Retrospective, single\u2010center analysis of 21 consecutive HeartMate 3 recipients implanted between 2016 and 2025 at external centers and subsequently evaluated in our department. All patients underwent CT\/CTA when device dysfunction was suspected. Failure modes were predefined and adjudicated using standardized imaging criteria. CT\/CTA was the primary modality used to confirm geometric failure modes following triggers such as low\u2010flow alarms, hemolysis, and abnormal chest radiography.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 21 HeartMate 3 recipients, inflow cannula malposition was identified in 7 patients, outflow graft kinking\/excessive length in 12, and aortic anastomotic stenosis in 2.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In this single\u2010center referral cohort, geometric failure modes were identified in 15 of 21 patients (71.4%) after HeartMate 3 implantation and showed reproducible CT\/CTA signatures. A standardized imaging\u2010driven diagnostic pathway may improve recognition of correctable geometric problems in patients referred for suspected device dysfunction; given the referral\u2010based design, these frequencies should not be interpreted as the true incidence in an unselected HeartMate 3 population.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/aor.70204","type":"journal-article","created":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T04:20:09Z","timestamp":1786681209000},"page":"1605-1615","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Geometry\u2010Related Technical Complications After\n                    <scp>LVAD<\/scp>\n                    Implantation: Impact on Device Dysfunction and Clinical Outcomes"],"prefix":"10.1111","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7774-5065","authenticated-orcid":false,"given":"Ali Saad","family":"Merzah","sequence":"first","affiliation":[{"name":"Department of Cardiac\u2010, Thoracic\u2010, Transplantation and Vascular Surgery Hannover Medical School  Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-8703-7140","authenticated-orcid":false,"given":"Ezin","family":"Deniz","sequence":"additional","affiliation":[{"name":"Department of Cardiac\u2010, Thoracic\u2010, Transplantation and Vascular Surgery Hannover Medical School  Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7571-3775","authenticated-orcid":false,"given":"Sara","family":"Knigge","sequence":"additional","affiliation":[{"name":"Department of Cardiac\u2010, Thoracic\u2010, Transplantation and Vascular Surgery Hannover Medical School  Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1434-6905","authenticated-orcid":false,"given":"Jasmin","family":"Hanke","sequence":"additional","affiliation":[{"name":"Department of Cardiac\u2010, Thoracic\u2010, Transplantation and Vascular Surgery Hannover Medical School  Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alina","family":"Zubarevich","sequence":"additional","affiliation":[{"name":"Department of Cardiac\u2010, Thoracic\u2010, Transplantation and Vascular Surgery Hannover Medical School  Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-8275-9843","authenticated-orcid":false,"given":"Mohamad","family":"Dia","sequence":"additional","affiliation":[{"name":"Duisburg Cardiac Surgery Center  Duisburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9847-7760","authenticated-orcid":false,"given":"Chaikovska","family":"Sofia","sequence":"additional","affiliation":[{"name":"Kyiv Heart Institute  Kyiv Ukraine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-2047-4447","authenticated-orcid":false,"given":"Todurov","family":"Borys","sequence":"additional","affiliation":[{"name":"Kyiv Heart Institute  Kyiv Ukraine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0646-0465","authenticated-orcid":false,"given":"Saeed","family":"Torabi","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Intensive Care Medicine University Hospital of Cologne  Cologne Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bastian","family":"Schmack","sequence":"additional","affiliation":[{"name":"Department of Cardiac\u2010, Thoracic\u2010, Transplantation and Vascular Surgery Hannover Medical School  Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Weymann","sequence":"additional","affiliation":[{"name":"Department of Cardiac\u2010, Thoracic\u2010, Transplantation and Vascular Surgery Hannover Medical School  Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zurab","family":"Darbaidze","sequence":"additional","affiliation":[{"name":"Department of Cardiac\u2010, Thoracic\u2010, Transplantation and Vascular Surgery Hannover Medical School  Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josephina","family":"Haunschild","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Rostock Heart Center University Medical Center Rostock  Rostock Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian D.","family":"Etz","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Rostock Heart Center University Medical Center Rostock  Rostock Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Max","family":"Biewer","sequence":"additional","affiliation":[{"name":"Department of Cardiac\u2010, Thoracic\u2010, Transplantation and Vascular Surgery Hannover Medical School  Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arjang","family":"Ruhparwar","sequence":"additional","affiliation":[{"name":"Department of Cardiac\u2010, Thoracic\u2010, Transplantation and Vascular Surgery Hannover Medical School  Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan D.","family":"Schmitto","sequence":"additional","affiliation":[{"name":"Department of Cardiac\u2010, Thoracic\u2010, Transplantation and Vascular Surgery Hannover Medical School  Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5984-9426","authenticated-orcid":false,"given":"G\u00fcnes","family":"Dogan","sequence":"additional","affiliation":[{"name":"Department of Cardiac\u2010, Thoracic\u2010, Transplantation and Vascular Surgery Hannover Medical School  Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,13]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2017.01.045"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2015.03.001"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.23736\/S0021\u20109509.22.12445\u20106"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/aor.14689"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/aor.14165"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2023.1143886"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCHEARTFAILURE.117.004325"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAT.0000000000002197"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12410\u2010020\u201009546\u2010y"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm12062430"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/aor.12394"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/aor.14413"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1313385"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2023.23204"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc1401768"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2012.05.004"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics14121259"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/aor.14970"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/aor.70070"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/ehf2.15410"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.2174\/1573403x1103150514151750"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2016.03.013"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2015.09.083"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/aor.13815"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525\u20101594.1993.tb00407.x"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/aor.12170"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.4103\/heartviews.heartviews_20_25"}],"container-title":["Artificial Organs"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aor.70204","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/aor.70204","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aor.70204","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T07:44:12Z","timestamp":1793346252000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/aor.70204"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,13]]},"references-count":27,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2026,11]]}},"alternative-id":["10.1111\/aor.70204"],"URL":"https:\/\/doi.org\/10.1111\/aor.70204","archive":["Portico"],"relation":{},"ISSN":["0160-564X","1525-1594"],"issn-type":[{"value":"0160-564X","type":"print"},{"value":"1525-1594","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,13]]},"assertion":[{"value":"2026-03-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-08","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-13","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}