{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T05:20:30Z","timestamp":1788153630744,"version":"build-2803163510"},"reference-count":48,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,8,30]],"date-time":"2026-08-30T00:00:00Z","timestamp":1788048000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,8,30]],"date-time":"2026-08-30T00:00:00Z","timestamp":1788048000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Artificial Organs"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Patients with advanced heart failure or severe ventricular dysfunction are often considered prohibitively high risk for non\u2010cardiac surgery. Impella may provide temporary perioperative hemodynamic support by augmenting cardiac output and unloading the left ventricle, but evidence for this strategy remains limited and largely case based.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a scoping review of Impella use for adult high\u2010risk non\u2010cardiac surgery. MEDLINE and Embase were searched from inception to April 2026, with supplementary hand\u2010searching and citation tracking. Eligible reports were synthesized descriptively, with particular attention to implantation timing, operative context, device strategy, outcomes, and complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Twenty\u2010three publications comprising 36 unique patients were identified. Evidence consisted mainly of case reports and small series. Impella was used across bariatric, abdominal, oncological, endocrine, transplant\u2010related, vascular, orthopedic, and neurosurgical procedures. Clinical strategies included planned pre\u2010emptive support, surgery during established Impella or ECMELLA support, rescue implantation after perioperative deterioration, and combined support strategies. Operative completion was usually reported and 34 of 36 unique published patients survived to hospital discharge; however, this reflects selected published experience rather than a reliable estimate of effectiveness or safety.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Impella\u2010supported non\u2010cardiac surgery appears technically feasible in highly selected patients treated in specialist centers. Current evidence supports feasibility, not comparative benefit or generalizable safety. Prospective multicenter data with standardized reporting are required before wider adoption can be justified.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/aor.70219","type":"journal-article","created":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T04:43:16Z","timestamp":1788151396000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["<scp>SURGELLA:<\/scp>\n                    A Scoping Review of Impella\u2010Assisted Hemodynamic Support in High\u2010Risk Non\u2010Cardiac Surgery"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8312-2895","authenticated-orcid":false,"given":"Hussein","family":"Elghazaly","sequence":"first","affiliation":[{"name":"Barts Heart Centre, St Bartholomew's Hospital Barts Health NHS Trust  London UK"},{"name":"William Harvey Research Institute Queen Mary University of London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3565-1853","authenticated-orcid":false,"given":"Mohammed","family":"Allaf","sequence":"additional","affiliation":[{"name":"Royal Brompton and Harefield Hospitals Guy's and St Thomas' NHS Foundation Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4035-4052","authenticated-orcid":false,"given":"Areeb","family":"Mian","sequence":"additional","affiliation":[{"name":"Nuffield Department of Surgical Sciences, John Radcliffe Hospital University of Oxford  Oxford UK"},{"name":"Department of Hepato\u2010Pancreato\u2010Biliary Surgery Oxford University Hospitals NHS Foundation Trust  Oxford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanad","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Royal Papworth Hospital NHS Foundation Trust  Cambridge UK"},{"name":"Department of Medicine University of Cambridge  Cambridge UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2997-4194","authenticated-orcid":false,"given":"Alex","family":"Gordon\u2010Weeks","sequence":"additional","affiliation":[{"name":"Nuffield Department of Surgical Sciences, John Radcliffe Hospital University of Oxford  Oxford UK"},{"name":"Department of Hepato\u2010Pancreato\u2010Biliary Surgery Oxford University Hospitals NHS Foundation Trust  Oxford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Tindale","sequence":"additional","affiliation":[{"name":"Royal Brompton and Harefield Hospitals Guy's and St Thomas' NHS Foundation Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9894-9200","authenticated-orcid":false,"given":"Vasileios","family":"Panoulas","sequence":"additional","affiliation":[{"name":"Royal Brompton and Harefield Hospitals Guy's and St Thomas' NHS Foundation Trust  London UK"},{"name":"National Heart and Lung Institute Imperial College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,30]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000018144"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13054\u2010015\u20100932\u20107"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000001285"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2016.03.004"},{"issue":"4","key":"e_1_2_13_6_1","doi-asserted-by":"crossref","first-page":"1955","DOI":"10.1053\/j.jvca.2018.03.031","article-title":"Extracorporeal Membrane Oxygenation: Beyond Cardiac Surgery and Intensive Care Unit: Unconventional Uses and Future Perspectives","volume":"32","author":"Monaco F.","year":"2018","journal-title":"Journal of Cardiothoracic and Vascular 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