{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T05:09:58Z","timestamp":1790053798828,"version":"4.0.1"},"reference-count":33,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T00:00:00Z","timestamp":1789948800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T00:00:00Z","timestamp":1789948800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31900944"],"award-info":[{"award-number":["31900944"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Artificial Organs"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Artificial anal sphincters are an important option for patients with severe anal incontinence. However, existing artificial anal sphincters still present safety and effectiveness concerns in animal experiments and clinical applications. Based on these problems, a novel double uniform radial clamping artificial anal sphincter device was proposed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In this study, a novel double uniform radial clamping artificial anal sphincter device was designed. The constant\u2010force characteristics of the device and its mechanical interaction with intestinal tissue were evaluated using finite element analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The simulation results showed that the maximum equivalent stresses on the outer and inner surfaces of the intestinal wall were approximately 147 and 159\u2009kPa, respectively. Regions of elevated equivalent stress were mainly localized near the bilateral clamping regions. The reaction force of the shape memory alloy constant\u2010force mechanism reached a peak value of 6.23\u2009N at a displacement of 2.48\u2009mm. Over the displacement range of 3.25\u20136.35\u2009mm, the reaction force remained between 5.78 and 6.07\u2009N, with a mean value of approximately 5.89\u2009N, indicating an approximately constant\u2010force plateau.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The proposed artificial anal sphincter provides a novel double uniform radial clamping design. Finite element analysis characterized the local mechanical response of the intestinal wall and the constant\u2010force behavior of the device, providing preliminary mechanical information for further experimental optimization and in\u00a0vivo validation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/aor.70253","type":"journal-article","created":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T04:46:16Z","timestamp":1790052376000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A New Double Uniform Radial Clamping Artificial Anal Sphincter Device"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2957-3211","authenticated-orcid":false,"given":"Minghui","family":"Wang","sequence":"first","affiliation":[{"name":"Institute of Intelligent Rehabilitation Engineering University of Shanghai for Science and Technology  Shanghai China"},{"name":"Shanghai Engineering Research Center of Assistive Devices  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yinhao","family":"Wang","sequence":"additional","affiliation":[{"name":"Institute of Intelligent Rehabilitation Engineering University of Shanghai for Science and Technology  Shanghai China"},{"name":"Shanghai Engineering Research Center of Assistive Devices  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siyuan","family":"Chen","sequence":"additional","affiliation":[{"name":"Institute of Intelligent Rehabilitation Engineering University of Shanghai for Science and Technology  Shanghai China"},{"name":"Shanghai Engineering Research Center of Assistive Devices  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongliu","family":"Yu","sequence":"additional","affiliation":[{"name":"Institute of Intelligent Rehabilitation Engineering University of Shanghai for Science and Technology  Shanghai China"},{"name":"Shanghai Engineering Research Center of Assistive Devices  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,21]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2014.396"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.3389\/fsurg.2024.1340720"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.12688\/f1000research.15270.2"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1159\/000541355"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1159\/000541600"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.3393\/ac.2017.33.5.161"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/dcr.0000000000000709"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/dcr.0000000000001683"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1055\/s\u20102005\u2010864078"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1055\/s\u20100032\u20101315109"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471\u20102482\u201013\u201045"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.4721"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sna.2005.10.018"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525\u20101594.2010.01186.x"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/aor.12874"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/aor.13924"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.5301\/ijao.5000308"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1049\/iet\u2010smt.2015.0037"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1586\/erd.12.38"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1080\/13645700600836695"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000658\u2010199907000\u201000007"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/aor.14863"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/aor.14917"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmbbm.2020.104116"},{"key":"e_1_2_11_26_1","volume-title":"1st IEEE RAS\u2010EMBS International Conference on Biomedical Robotics and Biomechatronics (BioRob 2006)","author":"Natali A. 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